Éditeur(s) : HAL CCSD Public Library of Science
Résumé : Key message Molecular markers were used for paternity recovery in a maritime pine (Pinus pinasterAit.) polycross trial, facilitating forward selection. Different breeding strategies for seed orchard establishment were evaluated by comparing genetic gains and diversity. This work opens up new perspectives in maritime pine breeding.Context Polycross mating designs are widely used in forest tree breeding to evaluate parental breeding values for backward selection. Alternatively, polycross progeny trials may be used to select the best trees on the basis of individual breeding values and molecular pedigree analysis.Aims This study aimed to test such a forward selection strategy for the maritime pine breeding program.Methods In a maritime pine polycross trial, progeny with higher breeding values for growth and stem straightness was first preselected with or without relatedness constraints. After paternity recovery, the preselected trees were ranked on the basis of their breeding values, estimated from the recovered full pedigree. Finally, the best candidates were selected with three different strategies (forward, backward, mixed) and three levels of coancestry constraints to establish a virtual clonal seed orchard.Results Complete pedigrees were successfully recovered for most of the preselected trees. There was no major difference in expected genetic gains between the two preselection strategies which differed for relatedness constraints. Genetic gains were slightly higher for forward selection than for classical backward selection.Conclusion This seminal study opens up new perspectives for using forward selection within the French maritime pine breeding program.
ISSN: 1932-6203

hal-01601804
https://hal.archives-ouvertes.fr/hal-01601804
DOI : 10.1371/journal.pone.0049990
PRODINRA : 391860

Résumé : Le monde, depuis des millénaires, est bâti sur les fondations de sociétés bilingues. Or, ce « parler multiple » semble depuis toujours être source de conflit. Loin d’être considéré comme une richesse, le bilinguisme (ou plurilinguisme) semble plutôt représenter un problème auquel on tâcherait de trouver une solution. « La multiplicité » dit Louis-Jean Calvet (1999), « est chose mauvaise, on lui préfère de façon toute jacobine un bon gros Etat monolingue bien cerné dans ses frontières politiques et linguistiques ».La région caraïbe occupe une place tout à fait intéressante sur cette scène en perpétuel mouvement qu’est la mondialisation. Ces pays/îles doivent continuellement chercher l’équilibre entre appartenance locale, régionale et internationale, grand nombre d’entre eux luttant toujours aujourd’hui pour concilier leur statut d’anciennes colonies et le rythme rapide de la mondialisation. Cette thèse porte sur la place des langues vivantes dans les écoles du premier degré à la Martinique et à la Dominique et sur les enjeux d’un enseignement bilingue pour ces deux îles qui appartiennent à la fois à la Caraïbe et au monde. Nous proposons, dans un premier temps, une étude de la situation actuelle de l’enseignement des langues dans les deux îles : quelles sont les politiques linguistiques dans les deux contextes? Dans quelle mesure sont-elles mises en œuvre? L’enseignement des langues répond-il aux exigences des textes officiels ? Les politiques linguistiques sont-elles adaptées aux réalités sociolinguistiques de ces îles ? Dans un deuxième temps, nous interrogeons la possibilité d’un enseignement bilingue dès l’école préélémentaire dans les îles de la Martinique et de la Dominique et nous expérimentons des approches d’enseignement des langues en milieu institutionnel et en contexte périscolaire. Nous nous interrogeons sur des modes de fonctionnement différents : ne pourrait-on pas imaginer d’autres manières de faire ? Que pouvons-nous proposer comme solutions complémentaires et/ou alternatives à l’existant ?Enfin, dans un troisième temps, dans une perspective plus globale, nous posons la question de l’éducation bilingue, par une approche comparée, en analysant les faits éducatifs dans deux systèmes différents et en nous intéressant à la question de l’altérité. La compréhension de l’Autre peut-elle améliorer l’existant dans le cas de la Martinique et de la Dominique ? Nous revenons ainsi à la question de l’intérêt et des enjeux d’une comparaison de l’enseignement des langues dans ces deux systèmes, en prenant en compte les identités locales, régionales et internationales à travers des analyses historiques et sociolinguistiques. A la suite de cette analyse, nous faisons des propositions concrètes en faveur d’un enseignement bilingue intégré dans ces deux îles. Ces propositions concernent les domaines tels que la didactique, la planification en éducation et le curriculum bilingue, la formation des enseignants et la politique linguistique de la Caraïbe. Notre question centrale est la suivante : comment enseigner aujourd’hui pour mieux préparer les citoyens caribéens au monde de demain ?
The Caribbean region occupies an interesting space in the perpetually changing scene of globalisation. Caribbean countries or islands must continually seek to balance their sense of belonging to a local, regional and international community. This is sometimes a difficult task as any of them are still fighting to balance their evolution as old colonies with the fast pace of globalisation in a new world.This thesis focuses on language teaching at primary level in the islands of Martinique and Dominica. It examines the many issues surrounding language teaching and questions the role of bilingual education in the development of these two Caribbean islands as they evolve within the Caribbean and the world. Firstly, we propose a careful study of the current situation of language teaching in Martinique and Dominica. What are the language policies of these islands? How and to what extent are they implemented? Does language teaching truly reflect the objectives of official texts? Are the present language policies adapted to the sociolinguistic reality of each island?Secondly, we raise the question as to the possibility of the implementation of bilingual education at the pre-primary level in the islands of Martinique and Dominica. We examine the question through the experimenting of different language teaching methods within a school setting and as part of an extracurricular bilingual program. Can we envision alternative approaches to the present situation? What complementary or alternative solutions can we propose to improve on what already exists?Lastly, we look at the subject from an overall perspective and we address the question of bilingual education. We analyse how comparative education, the study of other education systems and the understanding of others play a major role in developing solutions to present day situations. This analysis takes into account issues relating to local, regional and international identities through a study of the historical and sociolinguistic context of the islands of Dominica and Martinique.Based on our analysis and on the literature, we put forward concrete proposals for holistic bilingual education on the islands of Martinique and Dominica. These proposals focus on areas such as language teaching pedagogy, education planning, the bilingual curriculum, teacher training, and language policy for the Caribbean. The main question underlying this thesis is: how do we teach today to better prepare Caribbean citizens for the world of tomorrow?

http://www.theses.fr/2015AGUY0834/document

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
Basal cell carcinoma (BCC) is the commonest tumor in human. About 70% sporadic BCCs bear somatic mutations in the PATCHED1 tumor suppressor gene which encodes the receptor for the Sonic Hedgehog morphogen (SHH). PATCHED1 germinal mutations are associated with the dominant Nevoid Basal Cell Carcinoma Syndrome (NBCCS), a major hallmark of which is a high susceptibility to BCCs. Although the vast majority of sporadic BCCs arises exclusively in sun exposed skin areas, 40 to 50% BCCs from NBCCS patients develop in non photo-exposed skin. Since overwhelming evidences indicate that microenvironment may both be modified by- and influence the- epithelial tumor, we hypothesized that NBCCS fibroblasts could contribute to BCCs in NBCCS patients, notably those developing in non photo-exposed skin areas. The functional impact of NBCCS fibroblasts was then assessed in organotypic skin cultures with control keratinocytes. Onset of epidermal differentiation was delayed in the presence of primary NBCCS fibroblasts. Unexpectedly, keratinocyte proliferation was severely reduced and showed high levels of nuclear P53 in both organotypic skin cultures and in fibroblast-led conditioning experiments. However, in spite of increased levels of senescence associated β-galactosidase activity in keratinocytes cultured in the presence of medium conditioned by NBCCS fibroblasts, we failed to observe activation of P16 and P21 and then of bona fide features of senescence. Constitutive extinction of P53 in WT keratinocytes resulted in an invasive phenotype in the presence of NBCCS fibroblasts. Finally, we found that expression of SHH was limited to fibroblasts but was dependent on the presence of keratinocytes. Inhibition of SHH binding resulted in improved epidermal morphogenesis. Altogether, these data suggest that the repertoire of diffusible factors (including SHH) expressed by primary NBCCS fibroblasts generate a stress affecting keratinocytes behavior and epidermal homeostasis. Our findings suggest that defects in dermo/epidermal interactions could contribute to BCC susceptibility in NBCCS patients.
ISSN: 1932-6203

Droits : http://creativecommons.org/licenses/by/
hal-01257867
http://hal.upmc.fr/hal-01257867
http://hal.upmc.fr/hal-01257867/document
http://hal.upmc.fr/hal-01257867/file/journal.pone.0145369.pdf
DOI : 10.1371/journal.pone.0145369

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The barrier reef tract of New Caledonia is the second largest in the world enclosing lagoons of variable width. The Late Quaternary evolution of these barrier reefs and lagoons is poorly known. A recent high resolution seismic and multibeam bathymetry survey was carried out in the south-western lagoon from shoreline to open ocean across the barrier reef pass systems to perform sequence stratigraphy and to better understand the Quaternary evolution of the lagoon. Two depositional sequences bounded by type-1 erosional surfaces can be identified. The bounding surfaces delineate the bottom of two generations of incised valleys. System tracts comprising a complete succession of regressive, lowstand, transgressive and highstand tracts were observed only in the upper sequence. Chronostratigraphic and sedimentological interpretations of the seismic data are based on correlations with the chronology defined in the nearby cores drilled through the reefs and in the gravity cores previously recovered in the inner lagoon. Interpretation of seismic data is also carried out on the basis of correlation with multibeam bathymetric data. Our results indicate that the history of the New Caledonian lagoon probably does not exceed 200ka marked by two or three brief episodes each of immersion of about ten thousand years. The bathymetric data reveal that during successive low sea level stands, the lagoon was dependent upon erosional fluvial networks. The deep fluvial valleys were connected to the continental slope through the passes. Seismic records reveal that upstream palaeo-channels are not connected to the modern coastal rivers. In contrast, many aggrading deposits, including numerous stacking channels, and extending across the proximal part of the outer lagoon, can be identified. Examination of drainage network morphology suggests a progressive tilt of the outer lagoon. Such evolution reveals that the Nouméa lagoon which is one of the widest in the world is an exceptional modern example of a rimmed shelf providing data to analyze the past counterparts.
ISSN: 0031-0182

insu-00338953
https://hal-insu.archives-ouvertes.fr/insu-00338953
DOI : 10.1016/j.palaeo.2008.08.012

Éditeur(s) : HAL CCSD European Geosciences Union
Résumé : International audience
During the GWADASEIS cruise (Lesser Antilles volcanic arc, February-March 2009) a very high resolution (VHR) seismic-reflection survey was performed in order to constrain Late Quaternary to Present faulting. The profiles we obtained evidence frequent "ponding" of reworked sediments in the deepest areas, similar to the deposition of Mediterranean "homogenites". These bodies are acoustically transparent (few ms t.w.t. thick) and are often deposited on the hanging walls of dominantly normal faults, at the base of scarps. Their thickness appears sufficient to compensate (i.e. bury) co-seismic scarps between successive earthquakes, resulting in a flat and horizontal sea floor through time. In a selected area (offshore Montserrat and Nevis islands), piston coring (4 to 7 m long) was dedicated to a sedimentological analysis of the most recent of these particular layers. It corresponds to non-stratified homogenous calcareous silty sand (reworked calcareous plankton and minor volcanoclastics). This layer can be up to 2 m thick, and overlies finegrained hemipelagites. The upper centimeters of the latter represent the normal RedOx water/sediment interface. 210Pb and 137Cs activities lack in the massive sands, while a normal profile of unsupported 210Pb decrease is observed in the hemipelagite below, together with a 137Cs peak correspond- ing to the Atmospheric Nuclear Experiments (1962). The RedOx level was thus capped by a recent instantaneous major sedimentary event considered as post-1970 AD; candidate seismic events to explain this sedimentary deposits are either the 16 March 1985 earthquake or the 8 October 1974 one (Mw=6.3 and Mw=7.4, respectively). This leads to consider that the syntectonic sedimentation in this area is not continuous but results from accumulation of thick homogenites deposited after the earthquakes (as observed in the following weeks after Haiti January 2010 event, McHugh et al., 2011). The existence of such deposits suggests that, in the area of study, vertical throw likely results from cumulated effects of separated earthquakes rather than from aseismic creep. Examination of VHR profiles shows that all major co-seismic offsets are recorded in the fault growth sequence and that co-seismic offsets can be precisely estimated. By using a sedimentation rate deduced from 210Pb decrease curve (0.5 mm yr−1) and taking into account minor reworking events detected in cores, we show that the Redonda system may have been responsible for five >M6 events during the last 34 000 yr. The approach presented in this work differs from fault activity analyses using displaced sets of isochronous surfaces and postulating co-seismic offsets. Combining VHR seismic imagery and coring we can decipher co-seismic vs. slow continuous displacement, and thus actually estimate the amplitude and the time distribution of major co-seismic offsets.
ISSN: 1561-8633

insu-00844581
https://hal-insu.archives-ouvertes.fr/insu-00844581
https://hal-insu.archives-ouvertes.fr/insu-00844581/document
https://hal-insu.archives-ouvertes.fr/insu-00844581/file/nhess-12-1755-2012.pdf
DOI : 10.5194/nhess-12-1755-2012

Éditeur(s) : Gauthier-Villars
Résumé : The littoral area of Benin is a lagoonal-estuarial, indeed even deltaic, environment. Poor in species, the mangrove of Benin belongs to the tropical Atlantic type tending to be humid, considering the "drought belt" which affects this region. It undergoes profound hydrological changes in the course of the different seasons in relation to the Mono and Couffo Rivers. The granulometric analysis and the study of the facies makes clear a lenticular-type sedimentation in relation to numerous and rapid hydrodynamic variations. The clayish quartzose sediment also contains a chemical phase (pyrite is transformed through oxidation into jarosite, gypsum and halite in relation to the micromilieux of evaporation) and an important organic phase - with a pH level ranging from 5 to 6. Kaolinite, from the nearby "Continental terminal", is deposited during calm periods. The smectites seem linked to high energy, sandier deposits and their origin should probably be sought in a far away back country (Eocene, basement).
Oceanologica Acta, Special issue (0399-1784) (Gauthier-Villars), 1982

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/00246/35730/34238.pdf
http://archimer.ifremer.fr/doc/00246/35730/

Éditeur(s) : HAL CCSD American Society of Tropical Medicine and Hygiene
Résumé : International audience
Two cases are reported which illustrate important epidemiological aspects of lymphatic filariasis--prolonged longevity of the adult parasite and the possibility of transmission by individuals with ultra-low level microfilaremia. These cases demonstrate that people can remain carriers of microfilariae in the peripheral blood for many years without reinfection, and even those with a low level microfilaremia can constitute a significant reservoir of mosquito infection. Such cases represent one of the most serious obstacles to the eradication of lymphatic filariasis in regions where control is based on chemotherapy.
ISSN: 0002-9637

hal-00715427
https://hal.univ-antilles.fr/hal-00715427
PUBMED : 373472

Éditeur(s) : HAL CCSD Cambridge University Press (CUP)
Résumé : International audience
Background. Adverse psychosocial working environments characterized by job strain (the combination of high demands and low control at work) are associated with an increased risk of depressive symptoms among employees, but evidence on clinically diagnosed depression is scarce. We examined job strain as a risk factor for clinical depression. Method. We identified published cohort studies from a systematic literature search in PubMed and PsycNET and obtained 14 cohort studies with unpublished individual-level data from the Individual-Participant-Data Meta-analysis in Working Populations (IPD-Work) Consortium. Summary estimates of the association were obtained using random-effects models. Individual-level data analyses were based on a pre-published study protocol. Results. We included six published studies with a total of 27 461 individuals and 914 incident cases of clinical depression. From unpublished datasets we included 120 221 individuals and 982 first episodes of hospital-treated clinical depression. Job strain was associated with an increased risk of clinical depression in both published [relative risk (RR) = 1.77, 95% confidence interval (CI) 1.47-2.13] and unpublished datasets (RR = 1.27, 95% CI 1.04-1.55). Further individual participant analyses showed a similar association across sociodemographic subgroups and after excluding individuals with baseline somatic disease. The association was unchanged when excluding individuals with baseline depressive symptoms (RR = 1.25, 95% CI 0.94-1.65), but attenuated on adjustment for a continuous depressive symptoms score (RR = 1.03, 95% CI 0.81-1.32). Conclusions. Job strain may precipitate clinical depression among employees. Future intervention studies should test whether job strain is a modifiable risk factor for depression.
ISSN: 0033-2917

hal-01560152
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01560152
DOI : 10.1017/S003329171600355X
PUBMED : 28122650

Éditeur(s) : Pergamon-elsevier Science Ltd
Résumé : The environment is impacted by natural and anthropogenic disturbances that occur at different spatial and temporal scales, and that lead to major changes and even disequilibria when exceeding the resiliency capacities of the ecosystem. With an annual mean flow of 1700 m(3) s(-1), the Rhone River is the largest of the western Mediterranean basin. Its annual solid discharges vary between 2 and 20 Mt, with flood events responsible for more than 70% of these amounts. In the marine coastal area, close to the mouth, both flocculation and aggregation lead to the formation of fine-grained deposits, i.e. the prodelta. This area is characterized by sediment accumulation rates up to 20-50 cm yr(-1) and high accumulations of particle reactive contaminants such as various man-made radionuclides released into the river by nuclear facilities or arising form prior atmospheric nuclear tests (1954-1980) and the Chernobyl accident (April 1986). This prodelta, however, cannot be considered as a permanent repository for particle reactive pollutants since it is subjected to reworking processes. Sediment dynamics had to be linked to the influences of hydrodynamic and atmospheric events such as high flow rates or storms close to the Rhone River mouth. An experiment was carried out during the winter 2006 based on the deployment of two ADCPs and six altimeters at the Grand Rhone mouth for several months. This type of installation has never been used before in this area because of the hard meteorological conditions and the strong fishing activities. However, results showed pluricentimetric rises of the sedimentary level just after river flood events and decreases during storms, generated by southeast winds. Radiotracers and grain size depth profiles helped to characterise the studied events and to establish inventories of sediments and radionuclides. A cruise (CARMEX) was carried out during this same period to collect water samples, suspended particles and sediment cores. The results enabled us to link both river flow and wind characteristics to events recorded on the sea floor, i.e. resuspension, accumulation, consolidation, etc. Deposits of 11 cm of sediments were estimated during flood periods and bottom shear stresses up to 5 N m(-2) were calculated during sediment erosion phases. (C) 2010 Elsevier Ltd. All rights reserved.
Continental Shelf Research (0278-4343) (Pergamon-elsevier Science Ltd), 2010-05 , Vol. 30 , N. 9 , P. 1095-1107

Droits : 2010 Elsevier B.V. All rights reserved.
http://archimer.ifremer.fr/doc/00006/11695/8479.pdf
DOI:10.1016/j.csr.2010.02.015
http://archimer.ifremer.fr/doc/00006/11695/

Éditeur(s) : HAL CCSD Botanical Society of America
Résumé : Premise of the study : Wood density correlates with mechanical and physiological strategies of trees and is important for estimating global carbon stocks. Nonetheless, the relationship between branch and trunk xylem density has been poorly explored in neotropical trees. Here, we examine this relationship in trees from French Guiana and its variation among different families and sites, to improve the understanding of wood density in neotropical forests. Methods : Trunk and branch xylem densities were measured for 1909 trees in seven sites across French Guiana. A major-axis fit was performed to explore their general allometric relationship and its variation among different families and sites. Key results : Trunk xylem and branch xylem densities were significantly positively correlated, and their relationship explained 47% of the total variance. Trunk xylem was on average 9% denser than branch xylem. Family-level differences and interactions between family and site accounted for more than 40% of the total variance, whereas differences among sites explained little variation. Conclusions : Variation in xylem density within individual trees can be substantial, and the relationship between branch xylem and trunk xylem densities varies considerably among families and sites. As such, whole-tree biomass estimates based on non-destructive branch sampling should correct for both taxonomic and environmental factors. Furthermore, detailed estimates of the vertical distribution of wood density within individual trees are needed to determine the extent to which relying solely upon measures of trunk wood density may cause carbon stocks in tropical forests to be overestimated.
ISSN: 0002-9122

hal-01032401
https://hal.archives-ouvertes.fr/hal-01032401
DOI : 10.3732/ajb.1000034

Éditeur(s) : American Geophysical Union
Résumé : Thick forced regressive units on the wide continental shelf of the Gulf of Lions (western Mediterranean) recorded the composite effect of sea level changes during the Quaternary. They are mostly composed of coastal siliciclastic and bioclastic wedges showing clinoform geometry. These deposits have been intensively explored through high-resolution seismic investigations, but only recently it was possible to ground truth seismic interpretations, based on a long (100 m) borehole that crossed the succession and recovered a large part of the mainly sandy deposits (similar to 84% recovery). A multiproxy analysis of the sedimentary succession shows that (1) the stratal architecture of the shelf margin is defined by major bounding surfaces that are polygenic erosion surfaces associated with coarse-grained material incorporating abundant and diverse shells, including cold-water fauna (presently absent from the Mediterranean Sea). Between each surface, coarsening upward units with steep (up to 5 degrees) foresets are made of massive (more than 20 m thick) sands with possible swaley and hummocky cross-stratification, passing seaward to sands with muddy intervals and, further offshore, alternating highly boiturbated sands and silts. Each prograding wedge corresponds to a forced-regressive shoreface (or delta front/prodelta), deposited during the overall sea level falls occurring at (relatively slow) interglacial/glacial transition and therefore represents the record of 100 ka cyclicity. Higher-frequency Milankovitch cyclicities are also probably represented by distinct shoreface/delta front wedges; (2) detailed examination of the architecture and chronostratigraphy of the most recent sequence shows that minor bounding surfaces, corresponding to abrupt shallowing of sedimentary facies, separate downward stepping parasequences within the last 100 ka sequence. These events are in phase with millennial-scale glacial climatic and sea level variability, the downward shift surfaces corresponding to the falls during the coldest stadials. These deposits provide a comprehensive and well-constrained Pleistocene analog to the numerous shoreface deposits attributed to falling-stage systems tracts recognized in ancient stratigraphic records, studied at the outcrop scale.
Geochemistry Geophysics Geosystems - G3 (1525-2027) (American Geophysical Union), 2008-11 , Vol. 9 , N. Q11R05 , P. NIL_40-NIL_66

Droits : 2008 American Geophysical Union
http://archimer.ifremer.fr/doc/2008/publication-4929.pdf
DOI:10.1029/2007GC001854
http://archimer.ifremer.fr/doc/00000/4929/

Éditeur(s) : HAL CCSD Paris : Français dans le monde
Résumé : International audience
The description of the Common European Framework for Languages still varies from a country to another one, nvertheless it is based on seemingly to unambiguous formulations as "Can manage in the situations of the everday life" (CEFRL:66). Ths paper analyzes the methodes of design and the theorical, symbolic and systemic limits of scales, and it tries to define why the establishment of a set of common reference points for languages doesn't reach its goal of a consensual interpretation of the Common Reference Levels.
Nous explorons dans cet article les modalités de conception, les limites théoriques, symboliques et systémiques des échelles de compétence en langue du Cadre européen commun de référence pour les langues, afin de répondre à une question en apparence simple. Pourquoi les spécifications du Cadre, pourtant définies sur la base de descripteurs en apparence aussi univoques que "Peut se débrouiller dans les situations de la vie quotidienne" (Cadre:66) varient-elles autant d'un pays à l'autre ou d'une méthode FLE à l'autre?
ISSN: 0994-6632

Droits : info:eu-repo/semantics/OpenAccess
halshs-01400361
https://halshs.archives-ouvertes.fr/halshs-01400361
https://halshs.archives-ouvertes.fr/halshs-01400361/document
https://halshs.archives-ouvertes.fr/halshs-01400361/file/Les%20descripteurs%20de%20comp%C3%A9tence%20en%20langue%20rappels%20et%20mise%20en%20perspective.pdf

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
Questions: Several studies have described aggregated spatial patterns in tropical tree species. This study investigates aggregate dynamics of Vouacapoua americana (Aublet), a climax species whose spatial pattern is not simply related to light and soil conditions or to its short seed dispersal range. Location: Two rain forest sites: Nouragues and Paracou, in the Guiana Shield. Methods: We described the spatial pattern of tree locations and spatial autocorrelation of tree diameters, using statistics derived from Ripley's K. We particularly used methods to define analysis subplots according to local density or local mean diameter. We investigated relationships between spatial distributions of adults and saplings. Results: At both sites, populations of Vouacapoua demonstrated several nested levels of aggregation. Tree diameters were spatially autocorrelated, revealing the existence of clusters with similar diameters. In the largest aggregates, tree diameters declined from the centre to the edge. Regeneration was aggregated and occurred mainly at cluster edges and around rare isolated trees, and sapling densities and basal area of adults were negatively correlated. We show that long-distance dispersal events are rare. Conclusions: Environmental factors and seed dispersal only explain part of the observed spatial patterns. We provide two main hypotheses about Vouacapoua population dynamics. First, the lack of regeneration in aggregate centres results in the ageing of existing aggregates. We suggest that this lack of recruitment close to mature trees is due to a Janzen-Connell effect. However, aggregates can continue to grow along colonization fronts. Second, long-distance dispersal events allow the formation of new clusters and play a crucial role in the colonization process. We investigate aggregate dynamics of Vouacapoua americana (Aublet) whose spatial pattern is not simply related to environmental conditions or to its seed dispersal. Regeneration does not occur in centers of aggregate of adults. We suggest that rare long-distance dispersal events and density-dependence predation of seeds and seedlings play a crucial role in formation of new clusters and structuration of larger aggregates.
ISSN: 1100-9233

hal-01502642
https://hal-agroparistech.archives-ouvertes.fr/hal-01502642
DOI : 10.1111/jvs.12080

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Trivalent inorganic arsenic [As(III)] is an efficient anticancer agent used to treat patients suffering from acute promyelocytic leukemia. Recently, experimental studies have clearly demonstrated that this metalloid can also cure lymphoproliferative and/or pro-inflammatory syndromes in different murine models of chronic immune-mediated diseases. T helper (Th) 1 and Th17 lymphocytes play a central role in development of these diseases, in mice and humans, especially by secreting the potent pro-inflammatory cytokine interferon-γ and IL-17A, respectively. As(III) impairs basic functions of human T cells but its ability to modulate secretion of pro-inflammatory cytokines by differentiated Th lymphocytes is unknown. In the present study, we demonstrate that As(III), used at concentrations clinically achievable in plasma of patients, has no effect on the secretion of interferon-γ from Th1 cells but almost totally blocks the expression and the release of IL-17A from human Th17 lymphocytes co-stimulated for five days with anti-CD3 and anti-CD28 antibodies, in the presence of differentiating cytokines. In addition, As(III) specifically reduces mRNA levels of the retinoic-related orphan receptor (ROR)C gene which encodes RORγt, a key transcription factor controlling optimal IL-17 expression in fully differentiated Th17 cells. The metalloid also blocks initial expression of IL-17 gene induced by the co-stimulation, probably in part by impairing activation of the JNK/c-Jun pathway. In conclusion, our results demonstrate that As(III) represses expression of the major pro-inflammatory cytokine IL-17A produced by human Th17 lymphocytes, thus strengthening the idea that As(III) may be useful to treat inflammatory immune-mediated diseases in humans.
ISSN: 0041-008X

inserm-00872871
http://www.hal.inserm.fr/inserm-00872871
DOI : 10.1016/j.taap.2012.05.004
PUBMED : 22617429

Éditeur(s) : HAL CCSD Elsevier Masson
Résumé : International audience
We provide new constraints on the modes of mantle exhumation and denudation in the pre-orogenic Pyrenees by investigating the poorly known peridotites located east of the Lherz body, in eastern Ariè ge (Vicdessos, Urs, Bestiac, Caussou and Prades main peridotitic bodies). We show that: (1) numerous peridotite bodies, not described so far, are constituted by decametric to sub-metric outcrops scattered between and around the main outcrops identified by Monchoux (1970); (2) most of the peridotites form blocks and lenses of various sizes, from millimetric monocrystalline grains to hectometric olistoliths, embedded in debris flows involving mainly Mesozoic metasediments; these peridotites can therefore be linked to the S-type peridotites of Lagabrielle et al. (2010), and share similarities with the peridotites of Lherz region (Clerc et al., 2012). All originated from tectono-sedimentary processes associated with mantle exhumation in relation with extreme thinning and breakoff of the continental basement; (3) the various petrographic characters of these peridotites and their heterogeneity in serpentinisation degree imply a peculiar mode of exhumation, which merges mantle fragments inherited from different structural levels; (4) the lack of tectonic structures such as faults and shear planes associated with the ultramafic-rich breccia formation and the presence of neoformation of metamorphic minerals within the matrix preclude their origin as cataclasites related to the Latest Cretaceous and Tertiary Pyrenean contractional deformation. The peridotites of eastern Ariè ge are indisputable witnesses of the presence of an inverted hyper-extended Cretaceous passive margin forming the current North Pyrenean zone. The geometry of the extensional system was complex and probably associated with strike-slip faults and transcurrent motion. ß 2016 The Authors. Published by Elsevier Masson SAS on behalf of Acadé mie des sciences. This is an open access article under the CC BY-NC-ND license (http://creativecommons. org/licenses/by-nc-nd/4.0/).
ISSN: 1631-0713

Droits : http://creativecommons.org/licenses/by-nc-nd/
insu-01280502
https://hal-insu.archives-ouvertes.fr/insu-01280502
https://hal-insu.archives-ouvertes.fr/insu-01280502/document
https://hal-insu.archives-ouvertes.fr/insu-01280502/file/1-s2.0-S1631071316000043-main.pdf
DOI : 10.1016/j.crte.2015.12.003

Éditeur(s) : Actes du colloque, April 28-30 1997
Résumé : Due to favourable environmental conditions and political will, marine fish farming has developed recently around the Mediterranean. The Mediterranean area is characterised by a large number of islands which are extremely diversified from geographical, political or socioeconomic point of views. As a matter of fact, it turns out that almost a third of the Mediterranean fish farming production comes from these islands which have proven to offer good conditions for the development of that new activity. The reasons why somany enterprises have been established on islands are very diverse. Taking advantage of good environmental conditions is the most common motivation, since islands are usually less submitted to constraints due to town extension, industry development or intensive agriculture. Moreover, as far as European Union countries are concerned, incentive policy towards ultraperipheral or late development regions has made it possible to attribute specific subsidies to islands for aquaculture in the aim of more employment and wealth. Like any other economic activity, aquaculture has to face some specific constraints due to the insular context. Transport to and from the islands is more expensive and less regular, which has a negative impact on the price competitiveness of the insular products. Local markets are often too small to make it possible for the enterprises to develop first at a domestic level and to take advantage of economies of scale. Thanks to their positive and attractive world-wide image, Mediterranean islands could promote the quality of their products on the basis of geographical origin, of quality of the environment or of specific production processes. Information networks implementation and marketing approach in terms of image are challenges Mediterranean islands have to take up in order to supply the large European seafood market with quality products. [NOT CONTROLLED OCR]
Grâce à de bonnes conditions de milieu et à une volonté politique affirmée, l'élevage des poissons marins s'est développé récemment dans la Méditerranée. Le bassin méditerranéen possède un très grand nombre d'îles qui sont très diverses de par leur caractéristiques géographiques, politiques ou socio-économiques. Près du tiers de la production de poissons marins d'élevage des pays méditerranéens est réalisée dans des îles. Les raisons qui ont incité tant d'entreprises à s'établir sur des îles sont diverses. La motivation principale avancée par les promoteurs de l'aquaculture insulaire méditerranéenne est la qualité de l'environnement des îles et la disponibilité en sites, justifiée par le fait que les îles sont moins soumises à certaines contraintes comme l'extension des villes, le développement de zones industrielles ou l'intensification de l'agriculture. La politique d'aide envers les régions ultra-périphériques ou en retard de développement a permis d'attribuer des subventions spécifiques aux îles pour développer l'aquaculture dans un objectif de création de richesse et d'emploi. Comme toute autre activité économique dans les îles, l'aquaculture doit faire face à des contraintes directement liées à l'insularité. Le transport est plus coûteux et moins régulier, ce qui a un effet négatif sur la compétitivité prix des produits. Les marchés locaux sont souvent trop petits pour permettre aux entreprises de se développer d'abord en interne et de profiter d'économies d'échelle. Une réponse possible à cette contrainte de concurrence internationale pourrait être la promotion des produits sur la base de l'origine géographique,de la qualité de l'environnement ou de procédés de production spécifiques afin de valoriser l'image très positive et la notoriété de ces îles dans le monde entier. Les réseaux dédiés à l'information, à la recherche et au transfert technologique sont des outils nécessaires pour compenser les contraintes dues à la petite taille et à l'isolement dans le but de fournir le vaste marché européen en produits de la mer de qualité. [OCR NON CONTRÔLE]

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/1997/acte-4010.pdf
http://archimer.ifremer.fr/doc/00000/4010/

Éditeur(s) : HAL CCSD
Résumé : Coral reefs are amongst the richest and more emblematic ecosystems of the world. These hotspots of biodiversity provide many services to Human societies, bringing leisure and economic added values. In many areas, especially developing countries, these ecosystems are submitted to both climate change (rise of sea temperature and level, acidification) and human coastal pressures (urbanisation, resources exploitation). In this context, an increasing number of Marine Protected Areas is settled on coral reefs environments in order to ensure their conservation and to mitigate local pressures. Hence, one of MPAs Managers' missions is to bring ecological and social data together to build integrated indicators of effectiveness. In Reunion Island, a MPA called the Marine reserve of La Réunion was settled in 2007 along a densely urbanised and populated fringing reef coast. In order to better evaluate its MPA effectiveness, the manager requires the integration of social stakes to the management plan. A uses monitoring protocol was developed in this purpose using an ultra light aircraft and a camera. Data on 15 different recreational and non-recreational uses were acquired between 2010 and 2013, flying 48 times a year, and entered into a Geographic Information System. A huge resulting database allowed the building of an initial knowledge of the spatio-temporal distribution of uses within the Reserve. It also enabled the analysis of the uses' evolution regarding various factors of variations (amenities, facilities, shark attacks, tourism, etc.). Finally, we assessed the contribution to management efficiency using social indicators (governance, pressure indicators), and to interdisciplinary research in bringing ecologic and uses data together. This thesis brings a brand new information about coastal human activity and spatio-temporal dynamics of direct pressures on reef. This tool, designed to be reproducible and cost-optimized, enables the production of a set of indicators. Its integration to the management plan exclusively depends on the strategic choices of the manager.
Les récifs coralliens figurent parmi les biomes côtiers les plus emblématiques de la planète. Ces points chauds de la biodiversité mondiale sont convoités par les sociétés humaines pour leurs qualités paysagères et leur plus-value économique. Exposés au même titre que de nombreux écosystèmes côtiers aux changements climatiques (élévation de la température, acidification des océans), ils sont de toutes parts soumis à une anthropisation littorale mal maitrisée (urbanisation, surexploitation des ressources). Dans ce contexte, de plus en plus d' Aires Marines Protégées (AMP) s'établissent sur des écosystèmes anthropisés, les amenant à intégrer l'Homme au coeur de la gestion. À La Réunion où l'urbanisation littorale est dense et où le paysage des usages littoraux ne cesse de s’étoffer, une Réserve Naturelle Marine (RNMR) a été établie en 2007 sur un récif frangeant. L’évaluation de l’efficacité de cette AMP par son gestionnaire doit se faire par le biais d'un ensemble d'indicateurs écologiques et socio-économiques. C’est en vue d’apporter des connaissances sur la fréquentation et les usages pratiqués au sein de la RNMR que cette thèse a été initiée. Elaboré sur la base d'un suivi en ULM, un protocole a été reproduit chaque année entre 2010 et 2013 et a permis la constitution d'une base de données spatialisée, dont l'exploitation a produit trois types de résultats: i) une connaissance initiale de la répartition spatio-temporelle des usages au sein de la RNMR; ii) une compréhension de l'évolution des dynamiques spatio-temporelles à la lumière des facteurs de variations identifiés (aménagements, aménités, crise requin, tourisme, etc.), et iii) une contribution à la gestion par le développement d'indicateurs sociaux (gouvernance, pressions), et à la recherche interdisciplinaire par une confrontation des données de fréquentation et des données écologiques du milieu. La réflexion menée dans le cadre de cette thèse apporte un éclairage nouveau sur les usages et la fréquentation des littoraux coralliens à La Réunion, et leur traduction en termes de pression anthropique directe. Pensé pour être reproductible et optimisé en termes de coût, cet outil permet la production d’un ensemble d’indicateurs dont l’intégration au plan de gestion dépend exclusivement des choix stratégiques du gestionnaire.
https://tel.archives-ouvertes.fr/tel-01308703

Droits : http://creativecommons.org/licenses/by-nc-sa/
tel-01308703
https://tel.archives-ouvertes.fr/tel-01308703
https://tel.archives-ouvertes.fr/tel-01308703/document
https://tel.archives-ouvertes.fr/tel-01308703/file/Th%C3%A8se_Lemahieu.pdf

Éditeur(s) : HAL CCSD
Résumé : In an earlier paper, we developed an efficient incremental unknowns (IU) preconditioner for solving the two-dimensional (2D) Helmholtz problem in both high and low frequency (wavenumber) regimes. The multilevel preconditioning scheme involves separation of each grid into a coarser grid of the following level and a complementary grid on which the IUs are defined by interpolation. This approach is efficient as long as the mesh size of the coarsest grid is sufficiently small compared to the wavelength. In order to overcome this restriction, the authors introduced recently a modified IU method combining the conventional interpolation with the Helmholtz equation based interpolation (EBI). The EBI coefficients are derived numerically using a sufficiently large set of analytic solutions of the Helmholtz equation on a special hierarchy of stencils. The modified IUs using Helmholtz EBI are shown to provide improved preconditioning on the coarse scales where the conventional interpolation can not be employed. This study deals with the extension of this idea for solving the three-dimensional (3D) Helmholtz equation.
https://hal.univ-antilles.fr/hal-00763930

Droits : info:eu-repo/semantics/OpenAccess
hal-00763930
https://hal.univ-antilles.fr/hal-00763930
https://hal.univ-antilles.fr/hal-00763930/document
https://hal.univ-antilles.fr/hal-00763930/file/eci3D_3d.pdf

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
One of the main difficulties encountered when characterizing the hydrodynamic properties of a fractured aquifer is to identify the preferential flow paths within it. Different methods may be applied to determine the variability of the permeability at the borehole scale and to image the structure of the main flow zones between boreholes. In this paper, we compare the information obtained from different measurement techniques performed in a set of three 100 m depth wells (well-to-well spacing: 5­10 m) in a fractured crystalline rock setting. Geophysical logging and borehole-wall imaging are used to identify open and closed fractures intersecting the boreholes and their orientation. The comparison with flowmeter and single packer tests shows that few of the fractures interpreted as open from geophysical logs are significantly transmissive. Cross-borehole connectivity is first investigated from single packer tests with pressure monitoring in adjacent boreholes. To determine fracture zone connectivity, we propose a methodology simply based on the variation with packer depth of the ratio of the drawdown in the observation well and the drawdown in the pumping well. The results are compared to the analysis of cross-borehole flowmeter tests. We show that both methods provide consistent results with a similar level of information on connectivity.
ISSN: 0022-1694

insu-00221380
https://hal-insu.archives-ouvertes.fr/insu-00221380
DOI : 10.1016/j.jhydrol.2007.07.007

Éditeur(s) : HAL CCSD AGU and the Geochemical Society
Résumé : International audience
A NE-SW magnetotelluric 110 km-long profile including 18 sites was acquired across the western Rif Cordillera along the Eurasian-African plate boundary, allowing to constrain its poorly known deep structure. It extends from the Internal Zones, close to the Alboran coast, crossing the External Zones and up to the Gharb foreland basin. The periods recorded range from 0.001 s to 1000 s. The combination of magnetotelluric data with available geological data provides new insight regarding the relationship between deep and shallow crustal structures of the Rif Cordillera. Analyses of structural dimensionality suggest a preferential NW-SE direction, and a 2D joint inversion was performed. A 3D inversion extending the 2D model along the strike confirmed the reliability of this approach. The magnetotelluric model shows a heterogeneous upper crust in agreement with the geological structures observed at surface. The Internal Zones correspond to resistive (metamorphic rocks) and conductive (peridotites) bodies, while the External Zones and the foreland basin are characterized by large conductive bodies of variable thickness. A crustal detachment level separating shallow geological units from a probable variscan basement was inferred. At depth, the most relevant feature consists of large resistive bodies with a shallow irregular top, located below the frontal part of the Rif. The outcrops of exotic metapelitic, granitic and gneissic blocks in the frontal part of the Cordillera suggest that these large resistive bodies may correspond to a gneissic or granitic basement surrounded by metapelitic rocks. Late contractive thrust and diapiric processes were responsible for their uplift and shallow emplacement. The Rif constitutes an active southwestward vergent orogenic wedge, oblique to the present-day NW-SE convergent Eurasian-African plate boundary.
ISSN: 1525-2027

hal-00670999
https://hal.archives-ouvertes.fr/hal-00670999
DOI : 10.1029/2011GC003783