Résumé : Herbácea erecta perenne, glabra, comúnmente muy ramificada. Hojas alternas, ovadas a deltoideas, de hasta 30 cm, pinnati-compuestas, con divisiones filiformes; vainas peciolares de 3-10 cm de longitud. Inflorescencia en umbelas con muchas flores, de hasta 12 cm de diámetro; pétalos amarillos. Fruto oblongo, glabro, ligeramente compreso, con costillas agudas e iguales. Con frecuencia esta especie es confundida con Anethum graveolens, la cual tiene una vaina peciolar más corta y las costillas del fruto estrechamente aladas, las 2 laterales más amplias.
Herbacée dressée pérenne, glabre, habituellement très ramifiée. Feuilles alternes, ovées à triangulaires, pouvant atteindre 30 cm, pennati-composées, avec divisions filiformes. Inflorescence en ombelles avec de nombreuses fleurs, pouvant atteindre 12 cm de diamètre; pétales jaunes. Fruit oblong, glabre, légèrement comprimé, avec côtes aiguës. Cette espèce est fréquemment confondue avec Anethum graveolens, laquelle a une gousse pétiolaire plus courte et les 2 côtes latérales du fruit plus amples.
Erect perennial, glabrous branched herb up to 2 m tall. Leaves alternate with swollen sheaths 3-10 cm long, pale-edged and three or four times pinnatisect, forming fine thread-like segments; inflorescence in terminal umbels 12 cm diameter, flowers yellow 1-2 mm in diameter; fruit ovoid 5-6 mm long, greenish-brown with prominent ridges. This species is frequently confused with Anethum graveolens, in spite of the fact that the latter has a shorter petiolar sheath and its fruit features tightly winged ribs, the two side ribs being broader.
Nativa de la región mediterránea, cultivada y con frecuencia naturalizada en las regiones templadas y subtropicales del mundo.
Originaire de la région méditerranéenne, cultivée et fréquemment naturalisée dans les régions tempérées et subtropicales

http://www.tramil.net/fototeca/plant173

Éditeur(s) : Elsevier Science Bv
Résumé : During the Echolag cruise (13 February-8 March 2007), the effect of 16-30 knot trade winds on abundance, community structure and dynamics of phytoplankton was investigated in the southern part of the New Caledonian coral reefs and surrounding oceanic waters. In this area, the coral reefs form two horn-like structures (hereinafter referred to as 'horn reefs'), oriented south-east, and separated by a relatively deep valley. Three repeated samplings at one week intervals of a 32 station array showed that trade winds induce surface water cooling and significant enrichment of mid- and bottom waters above the reef shelf. This enrichment appeared as the result of a general rise of the oceanic thermocline and nitracline due to the combination of trade winds and tidally-generated internal waves between the horn reefs. It was accompanied by a factor of 1.5 and 2.3 mean increase for the chlorophyll concentration and picoplankton-nanoplankton cell number, respectively. From diel variations of in vivo chlorophyll a fluorescence and hourly sampling, phytoplankton gross growth rate was estimated to be 1-1.35 divisions per day and was quasi balanced with phytoplankton mortality for a 24 h period.
Journal Of Marine Systems (0924-7963) (Elsevier Science Bv), 2010-09 , Vol. 82 , N. 4 , P. 230-244

Droits : 2010 Elsevier B.V. All rights reserved.
http://archimer.ifremer.fr/doc/00013/12437/9258.pdf
DOI:10.1016/j.jmarsys.2010.05.010
http://archimer.ifremer.fr/doc/00013/12437/

Éditeur(s) : HAL CCSD
Résumé : LPSC14037
Scientific data collected with modern sensors or dedicated detectors exceed very often the perimeter of the initial scientific design. These data are obtained more and more frequently with large material and human efforts. A large class of scientific experiments are in fact unique because of their large scale, with very small chances to be repeated and to superseded by new experiments in the same domain: for instance high energy physics and astrophysics experiments involve multi-annual developments and a simple duplication of efforts in order to reproduce old data is simply not affordable. Other scientific experiments are in fact unique by nature: earth science, medical sciences etc. since the collected data is "time-stamped" and thereby non-reproducible by new experiments or observations. In addition, scientific data collection increased dramatically in the recent years, participating to the so-called "data deluge" and inviting for common reflection in the context of "big data" investigations. The new knowledge obtained using these data should be preserved long term such that the access and the re-use are made possible and lead to an enhancement of the initial investment. Data observatories, based on open access policies and coupled with multi-disciplinary techniques for indexing and mining may lead to truly new paradigms in science. It is therefore of outmost importance to pursue a coherent and vigorous approach to preserve the scientific data at long term. The preservation remains nevertheless a challenge due to the complexity of the data structure, the fragility of the custom-made software environments as well as the lack of rigorous approaches in workflows and algorithms. To address this challenge, the PREDON project has been initiated in France in 2012 within the MASTODONS program: a Big Data scientific challenge, initiated and supported by the Interdisciplinary Mission of the National Centre for Scientific Research (CNRS). PREDON is a study group formed by researchers from different disciplines and institutes. Several meetings and workshops lead to a rich exchange in ideas, paradigms and methods. The present document includes contributions of the participants to the PREDON Study Group, as well as invited papers, related to the scientific case, methodology and technology. This document should be read as a "facts finding" resource pointing to a concrete and significant scientific interest for long term research data preservation, as well as to cutting edge methods and technologies to achieve this goal. A sustained, coherent and long term action in the area of scientific data preservation would be highly beneficial.
http://hal.in2p3.fr/in2p3-00959072

in2p3-00959072
http://hal.in2p3.fr/in2p3-00959072
http://hal.in2p3.fr/in2p3-00959072/document
http://hal.in2p3.fr/in2p3-00959072/file/PREDON_Scientific_Data_Preservation_2014.pdf

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : En Haïti, l’accès difficile à des services spécialisés et la rareté des hôpitaux psychiatriques amènent l’aggravation des problèmes d’adaptation (IESM-OMS, 2011 ; Lecomte et Raphaël, 2010a; Nicolas et al.,). Certains services d’intervention tentent de répondre aux besoins complexes des enfants de la rue, comme par exemple le Centre d’accueil de Delmas 3. Au Québec, le modèle psychoéducatif guide les interventions spécialisées auprès de jeunes ayant des troubles de comportements. Le présent projet de recherche vise d’une part à évaluer si une approche collaborative favoriserait la pérennité d’un programme d’intervention en Haïti et d’autre part si le modèle psychoéducatif pourrait répondre aux besoins du milieu d’intervention du Centre d’accueil de Delmas. Pour favoriser la mobilisation des partenaires, le projet met de l’avant une méthode qualitative et collaborative (Hamel, Cousineau et Vézina, 2010). D’abord, une formation adaptée aux besoins du milieu a été présentée aux intervenants. Ensuite, l’équipe de recherche et les intervenants du centre d’accueil ont animé des activités psychoéducatives. Ce projet pilote a montré qu’une approche collaborative favorise la participation et le niveau de satisfaction de tous les acteurs impliqués. Cette expérience a également permis de constater que le modèle psychoéducatif pourrait être utilisé dans les centres d’accueil en Haïti. En effet, ce modèle permet d’adapter la réponse aux besoins des personnes selon les caractéristiques des milieux (Renou, 2005).
In Haiti, accessibility to specialized services and the lack of psychiatric hospitals exacerbates adaptation problems (Lecompte and Raphael 2010a; Nicolas et al, 2012; WHO-AIMS, 2011). The health professionals at the Centre d’accueil de Delmas 3 respond to the complex needs of young street children. In Quebec, several evidence-based intervention models have shaped our clinical practice for young children with behavior disorders. In fact, rehabilitation interventions are based on the psychoeducational model. The current research project had two goals: 1) Examine whether a collaborative approach would facilitate and ensure that the implementation of an intervention program would be ongoing and long-lasting in Haiti; 2) Explore whether the psychoeducational model could respond to the needs of a Haitian youth center. Qualitative methods were used to bring together partners in the research (Hamel, Cousineau and Vézina, 2010). First, educators followed a two days training developed to respond the specific needs. Second, interventions were implemented by researchers in collaboration with the stakeholders. This pilot project has shown that a collaborative approach encourages training and the level of participants' satisfaction. Futher, this experience showed that the psychoeducational model could very well fit the needs of a Haitian youth center. The psychoeducative model can yield responses adapted to the needs of people accounting for the characteristics of the environment (Renou, 2005).
Haïti

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.10295
http://journals.openedition.org/etudescaribeennes/10295

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
Challenging evaluation of tropical forest biodiversity requires the reporting of taxonomic diversity but also the systematic characterization of wood properties in order to discover new promising species for timber industry. Among wood properties, the dimensional stability is regarded as a major technological characteristic to validate whether a wood species is adapted to commercial uses. Cell structure and organization are known to influence the drying shrinkage making wood density and microfibrils angle markers of choice to predict wood dimensional stability. On the contrary the role of wood extractive content remains unclear. This work focuses on the fast-growing tropical species Bagassa guianensis and we report herein a correlation between heartwood drying shrinkage and extractive content. Chemical extractions and shrinkage experiments were performed on separate wood twin samples to better evaluate correctly how secondary metabolites influence the wood shrinkage behaviour. Extractive content were qualitatively and quantitatively analysed using HPLC and NMR spectroscopy. We found that B guianensis heartwood has a homogeneous low shrinkage along its radius that could not be explained only by its basic density. In fact the low drying shrinkage is correlated to the high extractive content and a corrected model to improve the prediction of wood dimensional stability is presented. Additionally NMR experiments conducted on sapwood and heartwood extracts demonstrate that secondary metabolites biosynthesis occurs in sapwood thus revealing B. guianensis as a Juglans-Type heartwood formation. This work demonstrates that B. guianensis, a fast-growing species associated with high durability and high dimensional stability, is a good candidate for lumber production and commercial purposes.
ISSN: 1932-6203

hal-01392725
https://hal.archives-ouvertes.fr/hal-01392725
https://hal.archives-ouvertes.fr/hal-01392725/document
https://hal.archives-ouvertes.fr/hal-01392725/file/2016_BossuBeaucheneEstevezDuplaisClair_PlosOne_WoodDimentionalStabilityAndSecondaryMetabolites.pdf
DOI : 10.1371/journal.pone.0150777.s005

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
The increased expression of the Disintegrin and Metalloprotease ADAM12 has been associated with human cancers, however its role remain unclear. We have previously reported that ADAM12 expression is induced by the transforming growth factor, TGF-β and promotes TGF-β-dependent signaling through interaction with the type II receptor of TGF-β. Here we explore the implication of ADAM12 in TGF-β-mediated epithelial to mesenchymal transition (EMT), a key process in cancer progression. We show that ADAM12 expression is correlated with EMT markers in human breast cancer cell lines and biopsies. Using a non-malignant breast epithelial cell line (MCF10A), we demonstrate that TGF-β-induced EMT increases expression of the membrane-anchored ADAM12L long form. Importantly, ADAM12L overexpression in MCF10A is sufficient to induce loss of cell-cell contact, reorganization of actin cytoskeleton, up-regulation of EMT markers and chemoresistance. These effects are independent of the proteolytic activity but require the cytoplasmic tail and are specific of ADAM12L since overexpression of ADAM12S failed to induce similar changes. We further demonstrate that ADAM12L-dependent EMT is associated with increased phosphorylation of Smad3, Akt and ERK proteins. Conversely, inhibition of TGF-β receptors or ERK activities reverses ADAM12L-induced mesenchymal phenotype. Together our data demonstrate that ADAM12L is associated with EMT and contributes to TGF-β-dependent EMT by favoring both Smad-dependent and Smad-independent pathways
ISSN: 1932-6203

hal-01207281
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01207281
DOI : 10.1371/journal.pone.0139179
PUBMED : 26407179

Éditeur(s) : HAL CCSD Elsevier
Résumé : Integrated field, LA-MC-ICP-MS geochronology and geochemical data from the Novo Oriente Group have been investigated in order to determine their provenance and possible tectonic setting. This group in the southwestern portion of the Ceara Central Domain, is a well-preserved metavolcanosedimentary sequence, in part exhalative, composed of two distinct formations. The proximal coastal Bonsucesso Formation comprises mainly quartzite and minor basic metavolcanic rocks and is in gradational contact with the distal Caranbas Formation which constitutes a metapelitic-volcanic-carbonate sequence, including metabasic rocks with pillow structure and sheared serpentinized ultrabasic rocks. The youngest detrital zircon found in the quartzite of the Bonsucesso Formation yielded an age of ca. 2.1 Ga and well-defined peaks around 2.2.2.3-2.4 and 2.5 Ga. In addition, zircons from a related metabasalt yielded an upper intercept age of 2083 +/- 28 Ma. We interpret the zircons found in this metabasalt as inherited from the host quartzite. This fact is supported by depleted-mantle Nd model ages (T-DM age) from correlated metabasic and metaultrabasic rocks from other places in the Novo Oriente sequence, which have yielded ages between 1.36 and 1.69 Ga, that is younger than the zircon age obtained in the metabasalt extruded over the Bonsucesso quartzite. Geochemical data of the metasedimentary rocks from the Caraubas Formation indicates a provenance composed of a mixture of felsic and intermediate sources typical of old stable cratons and older continental roots of active tectonic settings. The rocks of the Crania (Medio Coreau Domain) and Bacaja Complexes (southeastern Amazonian Craton) exposed to the west of the Novo Oriente Group, and largely covered by the Phanerozoic Parnaiba intracratonic basin, are the most likely source rocks. Since the precise age of the Novo Oriente Group is not yet well constrained, two distinct settings may be proposed: (1) it may represent a more evolved basin developed from extensional processes during the Mesoproterozoic (ca. 1.5-1.3 Ga); and (2) it could constitute part of the passive margin systems developed during the break-up of the Rodinia crown copyright supercontinent (ca. 0.95-0.8 Ga), associated with a pre-Brasiliano/Pan-African ocean (e.g. Pharusian Ocean). Crown.
ISSN: 1342-937X

hal-00512825
https://hal.archives-ouvertes.fr/hal-00512825
DOI : 10.1016/j.gr.2010.02.001

Éditeur(s) : Elsevier Science Bv
Résumé : The modern Rhone delta in the Gulf of Lions (NW Mediterranean) is a typical wave-dominated delta that developed after the stabilization of relative sea level following the last deglacial sea-level rise. Similar to most other deltas worldwide, it displays several stacked parasequences and lobes that reflect the complex interaction between accommodation, sediment supply and autogenic processes on the architecture of a wave-dominated delta. The interpretation of a large set of newly acquired very high-resolution seismic and sedimentological data, well constrained by 14C dates, provides a refined three-dimensional image of the detailed architecture (seismic bounding surfaces, sedimentary facies) of the Rhone subaqueous delta, and allows us to propose a scenario for delta evolution during the last deglaciation and Holocene. The subaqueous delta consists of “parasequence-like” depositional wedges, a few meters to 20–30 m in thickness. These wedges first back-stepped inland toward the NW in response to combined global sea-level rise and overall westward oceanic circulation, at a time when sediment supply could not keep pace with rapid absolute (eustatic) sea-level rise. At the the Younger Dryas-Preboreal transition, more rapid sea-level rise led to the formation of a major flooding surface (equivalent to a wave ravinement surface). After stabilization of global sea level in the mid-Holocene, accommodation became the leading factor controlling delta architecture. An eastward shift of depocenters occurred, probably favoured by higher subsidence rate within the thick Messinian Rhone valley fill. The transition between transgressive (backstepping geometry) and regressive (prograding geometry) (para)sequences resulted in creation of a Maximum Flooding Surface (MFS) that differs from a “classical” MFS described in the literature. It consists of a coarse-grained interval incorporating reworked shoreface material within a silty clay matrix. This distinct lithofacies results from condensation/erosion, which appears as an important process even within supply-dominated deltaic systems, due to avulsion of distributaries. The age of the MFS varies along-strike between ca. 7.8-5.6 kyr cal. BP in relation to the position of depocenters and climatically-controlled sediment supply. The last rapid climate change of the Holocene, the Little Ice Age (1250–1850 AD), had a distinct stratigraphic influence on the architecture and lithofacies of the Rhone subaqueous delta through the progradation of two deltaic lobes. In response to changes in sediment supply linked to rapid climate changes (and to anthropic factors), the Rhone delta evolved from wave-dominated to fluvial dominated, and then wave dominated again.
Sedimentary Geology (0037-0738) (Elsevier Science Bv), 2014-05 , Vol. 305 , P. 35-53

Droits : 2014 Elsevier B.V. All rights reserved.
http://archimer.ifremer.fr/doc/00179/29017/27445.pdf
DOI:10.1016/j.sedgeo.2014.02.004
http://archimer.ifremer.fr/doc/00179/29017/

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
BACKGROUND: Gastric cancer is one of the most common cancers in the world. The "economically developed countries" life style, including diet, constitutes a risk factor favoring this cancer. Diet modulation may lower digestive cancer incidence. Among promising food components, dairy propionibacteria were shown to trigger apoptosis of human colon cancer cells, via the release of short-chain fatty acids acetate and propionate. METHODOLOGY/PRINCIPAL FINDINGS: A fermented milk, exclusively fermented by P. freudenreichii, was recently designed. In this work, the pro-apoptotic potential of this new fermented milk was demonstrated on HGT-1 human gastric cancer cells. Fermented milk supernatant induced typical features of apoptosis including chromatin condensation, formation of apoptotic bodies, DNA laddering, cell cycle arrest and emergence of a subG1 population, phosphatidylserine exposure at the plasma membrane outer leaflet, reactive oxygen species accumulation, mitochondrial transmembrane potential disruption, caspase activation and cytochrome c release. Remarkably, this new fermented milk containing P. freudenreichii enhanced the cytotoxicity of camptothecin, a drug used in gastric cancer chemotherapy. CONCLUSIONS/SIGNIFICANCE: Such new probiotic fermented milk may thus be useful as part of a preventive diet designed to prevent gastric cancer and/or as a food supplement to potentiate cancer therapeutic treatments.
ISSN: 1932-6203

inserm-00871491
http://www.hal.inserm.fr/inserm-00871491
http://www.hal.inserm.fr/inserm-00871491/document
http://www.hal.inserm.fr/inserm-00871491/file/Milk_Fermented_by_Propionibacterium_freudenreichii.accepted.pdf
DOI : 10.1371/journal.pone.0031892

Éditeur(s) : HAL CCSD
Résumé : International audience
As subducting plates reach the base of the upper mantle, some appear to flatten and stagnate, while others seemingly go through unimpeded. This variable resistance to slab sinking has been proposed to affect long-term thermal and chemical mantle circulation. A review of observational constraints and dynamic models highlights that neither the increase in viscosity between upper and lower mantle (likely by a factor 20–50) nor the coincident endothermic phase transition in the main mantle silicates (with a likely Clapeyron slope of –1 to –2 MPa/K) suffice to stagnate slabs. However, together the two provide enough resistance to temporarily stagnate subducting plates, if they subduct accompanied by significant trench retreat. Older, stronger plates are more capable of inducing trench retreat, explaining why backarc spreading and flat slabs tend to be associated with old-plate subduction. Slab viscosities that are ∼2 orders of magnitude higher than background mantle (effective yield stresses of 100–300 MPa) lead to similar styles of deformation as those revealed by seismic tomography and slab earthquakes. None of the current transition-zone slabs seem to have stagnated there more than 60 m.y. Since modeled slab destabilization takes more than 100 m.y., lower-mantle entry is apparently usually triggered (e.g., by changes in plate buoyancy). Many of the complex morphologies of lower-mantle slabs can be the result of sinking and subsequent deformation of originally stagnated slabs, which can retain flat morphologies in the top of the lower mantle, fold as they sink deeper, and eventually form bulky shapes in the deep mantle.
ISSN: 1553-040X

hal-01571965
https://hal.archives-ouvertes.fr/hal-01571965
DOI : 10.1130/GES01476.1

Éditeur(s) : HAL CCSD Elsevier Masson
Résumé : International audience
Adult lymphatic filariae (Wuchereria bancrofti, Brugia malayi) can cause blocking of lymphatics producing obliterating endolymphitis lesions. The subsequent extravasation of lymph (or chyle when the obstruction is canal) is at the origin of the formation of lymphedema or elephantiasis, in which the main histological finding is great hypertrophy of collagen elements. This theory involving filaria only is not the full picture, and bacterial infection, mainly by streptococci, is an important factor. The association of filaria with microbes is particularly dangerous because the presence of the latter, or its toxins, causes death of local microfilariae and even adult worms, which are known to be more harmful dead than alive. The progression of the disease, especially in cases with lymphedema, which mainly affects the limbs and the genital organs, depends on three factors: the species of filaria, the degree of transmission, and the receptivity of the patient to the parasite. Large differences are found according to the region involved, and in the same endemic zone, according to the individuals affected. However, they almost always occur progressively in areas where there have been recurrent attacks of acute lymphangitis.
ISSN: 0398-0499

hal-00715440
https://hal.univ-antilles.fr/hal-00715440
PUBMED : 7007545

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Both oedometric and plane-strain tests were performed with parallelepipedic samples made of synthetic granular, cohesive, frictional and dilatant rock analogue material GRAM2. For the first time parallel sets of fractures that have all the characteristics of natural joints were reproduced in the laboratory. The fractures are regularly spaced, normal to σ3, and have plumose morphology very similar to that of natural joints. These fractures can form at tensile stress σ3 much smaller in magnitude than the tensile strength of material and even at slightly compressive σ3. When mean stress σ exceeds a certain value, the fractures become oblique to σ1 (the obliquity increases with σ), forming networks of conjugate shear bands/fractures. These results of plane-strain experiments are in good agreement with those of better controlled conventional axisymmetric tests on a similar material in Chemenda et al. (2011b) and are closer to real geological situations. Both types of experiments are complementary. Their results lead to the conclusion that at least certain categories of natural fractures (including joints, and conjugate shear fractures/bands) were initiated as deformation localization bands. The band orientation is defined by the constitutive properties/parameters (notably the dilatancy factor) that are sensitive to σ.
ISSN: 0040-1951

hal-00795555
https://hal.archives-ouvertes.fr/hal-00795555
DOI : 10.1016/j.tecto.2011.11.021

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
TIF1γ (Transcriptional Intermediary Factor 1 γ) has been implicated in Smad-dependent signaling by Transforming Growth Factor beta (TGF-β). Paradoxically, TIF1γ functions both as a transcriptional repressor or as an alternative transcription factor that promotes TGF-β signaling. Using ordinary differential-equation models, we have investigated the effect of TIF1γ on the dynamics of TGF-β signaling. An integrative model that includes the formation of transient TIF1γ-Smad2-Smad4 ternary complexes is the only one that can account for TGF-β signaling compatible with the different observations reported for TIF1γ. In addition, our model predicts that varying TIF1γ/Smad4 ratios play a critical role in the modulation of the transcriptional signal induced by TGF-β, especially for short stimulation times that mediate higher threshold responses. Chromatin immunoprecipitation analyses and quantification of the expression of TGF-β target genes as a function TIF1γ/Smad4 ratios fully validate this hypothesis. Our integrative model, which successfully unifies the seemingly opposite roles of TIF1γ, also reveals how changing TIF1γ/Smad4 ratios affect the cellular response to stimulation by TGF-β, accounting for a highly graded determination of cell fate.
ISSN: 1932-6203

hal-00851483
https://hal.archives-ouvertes.fr/hal-00851483
https://hal.archives-ouvertes.fr/hal-00851483/document
https://hal.archives-ouvertes.fr/hal-00851483/file/pone.0033761.pdf
DOI : 10.1371/journal.pone.0033761

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Cet article analyse les déterminants de la disposition des managers à formaliser les PME informelles en Côte d’Ivoire. Les données utilisées portent sur 400 entreprises du secteur informel enquêtées dans le cadre du projet CAPEC/CRDI. À partir des statistiques descriptives et de l’estimation d’un modèle Probit, l’étude met en évidence d’une part les variables qui influencent négativement et d’autre part celles qui influencent positivement la disposition à formaliser les PME. Il ressort de ces enquêtes que les taxes, le fait que l’entreprise soit dirigée par une femme, les coûts d’enregistrement, l’affiliation à une organisation politique et l’ignorance des procédures ont un effet négatif sur la disposition des managers à formaliser leurs entreprises. Les résultats montrent que la possession d’un plan d’affaires à la création, l’expérience du manager, la localisation, le niveau d’instruction supérieur, la simplification des procédures d’enregistrement affectent positivement la propension à formaliser les PME informelles. De même, les problèmes d’accès au financement et aux marchés publics conduisent les managers à la formalisation de leurs entreprises. Au regard de ces déterminants, la réduction des coûts de la formalisation, un meilleur accès des PME qui se formalisent au financement et aux marchés publics, le renforcement des capacités des opérateurs de l’informel, l’instauration d’une fiscalité incitative et la vulgarisation des procédures de déclaration s’avèrent des leviers importants de la formalisation.
This paper analyzes the determinants of the willingness of managers to formalize informal SMEs in Côte d'Ivoire. The data used relate to 400 informal sector enterprises surveyed under the CAPEC / IDRC project. On the basis of descriptive statistics and the estimation of a Probit model, the study highlights both variables that negatively influence and those that positively influence the willingness to formalize SMEs. These surveys show that taxes, the fact that the company is headed by a woman, registration costs, affiliation to a political organization and ignorance of procedures have a negative effect on the formalization of businesses.Moreover, the results show that ownership of a business plan at creation, managerial experience, location, higher education, simplification of registration procedures positively affect the propensity to formalize informal SMEs. Similarly, the problems of access to finance and public procurement lead to more formalization. In view of these determinants, the reduction in the costs of formalization, better access by SMEs to financing and public procurement, capacity building for informal operators, the introduction of tax incentives and the Dissemination procedures are important levers of formalization.
Côte d’Ivoire

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.10358
http://journals.openedition.org/etudescaribeennes/10358

Éditeur(s) : HAL CCSD Mineralogical Society of America
Résumé : International audience
To constrain the crystallization of alkaline and volatile-rich lavas present in intraplate settings, we studied the petrological features and the geochemical composition of major, trace, and volatile elements of mineral and bulk-rock of two sodalite-bearing phonolites: (1) haüyne-plagioclase-bearing Si-K-rich phonolite from Laacher See (Germany) and (2) nosean-nepheline-bearing Si-poor phonolite from Saghro (Morocco). In haüyne-bearing phonolites (55–59 wt% SiO2, K > Na, Na+K/Al = 0.96–1.08), we found that the low silica and low sodium activity promoted the early crystallization of S-rich haüyne (13.7–13.9 wt% SO3, 0.4 wt% Cl) + S-rich apatite (0.7–0.9 wt% SO3), titanite, and rare pyrrhotite followed by clinopyroxene-plagioclase-sanidine at relatively low pressure and temperature (P = 250 MPa and T = 850 °C) and oxidized condition (ΔNNO-NNO+1, where NNO is nickel-nickel oxide buffer). The crystallization of haüyne occurred at fluid-undersaturated conditions from a silicate melt with 6 wt% H2O, 0.17–0.23 wt% Cl, 0.11–0.4 wt% S, and 0.07–0.14 wt% F. Nosean-bearing phonolites from Saghro are silica-poor and peralkaline (52–54 wt% SiO2, Na > K, Na+K/Al = 1.2) and crystallized at higher P and T (300 MPa and 950 °C) and more reduced conditions (NNO) compared to haüyne-bearing phonolites. The incongruent reaction to form nosean requires high silica and Na2O activity. The mineral assemblage and composition suggest early crystallization of nepheline followed by nosean (7.8–8.8 wt% SO3; 1–1.1 wt% Cl). The sequence of crystallization is: clinopyroxene + nepheline + S-poor apatite (<0.04 wt% SO3) + pyrrhotite followed by nosean and titanite. Nosean-bearing magmas are fluid-undersaturated with relatively low volatile content (4 wt% H2O, <0.25 wt% Cl, <0.056 wt% S, 0.08–0.1 wt% F), although Cl may have exsolved during ascent and formed a fluid phase (NaCl-bearing).Both haüyne- and nosean-bearing phonolites are last equilibrated at relatively low pressure and high temperature. Haüyne and nosean crystallized at oxidized and volatile-rich pre-eruptive conditions. They record the volatile concentrations at depth and may be used as oxybarometer. The incongruent reactions involved to form haüyne and nosean suggest that phonolitic magmas became more oxidized during crystallization. The initial volatile concentrations in basanite/nephelinite magmas, from partial melting of volatile-bearing K2O-rich mantle rock, should have been one important factor influencing the crystallization of haüyne-bearing Si-K-rich phonolite and nosean-bearing Si-poor phonolite in intracontinental setting.
ISSN: 0003-004X

hal-01278067
https://hal.archives-ouvertes.fr/hal-01278067
DOI : 10.2138/am-2015-5318

Éditeur(s) : Université de Bretagne Occidentale
Résumé : The negative impact of the man on the environment unquestionably increases. The coastal environment as a whole is the maritime environment which is the most exposed to man-made eutrophication. For instance, nitrate loads to coastal waters off Brittany (France) have increased 10 times (from 3 to s 30mg L-1NO3) during the four last decades. Eutrophication of this coastal zone is now a recurrent problem, more and more worrying. This eutrophication exhibits two main forms : " green tides ", which are caused by local proliferations and stranding of green macro-algae (particularly the Ulva species) in nitrogen-enriched areas ; phytoplanktonic blooms, which are responsible for coloured water events, toxic species can be present (Pseudo-Nitzschia, Alexandrium, Dinophysis), and induce banning of shellfish consumption. The objectives of this study are to assess the respective role of various rivers (especially the Loire and the Vilaine) in the eutrophication of the Brittany shelf ecosystem and test the impact of nitrogen enrichment in the triggering of Pseudo-Nitzchia toxicity. For these purposes, a coupled hydrodynamical/ biogeochemical 3D model has been developed and validated against past measured time-series and satellite images. After a brief analysis of primary production over the Brittany shelf under different conditions, we show a description of the real time adaptation of this model. Daily results are currently presented in real time on www.previmer.org web site. The inability of the model to correctly simulate near shore phytoplankton is worsened in this model by the fact that the turbidity field used is a climatological one, made by satellite images averaged on a decadal basis. First, near shore pixels of satellite images are scarcely reliable, secondly a climatological mean cannot represent the sudden bursts or drops of the real turbidity, highly dependent on the actual sea-state : this can explain also why the model at this moment fails to reproduce a sudden bloom occurring in a short period of sunny and calm weather. The simulated Pseudo-Nitzschia biomass and induced risk of toxicity in the water column cannot really be validated offshore, because monitoring measurements are available only near the coast, and deal only with toxicity in benthic filter feeders. To get temporarily rid of that problem, an interesting improvement would be to add to the operational model the bio-accumulation of toxin in the shellfishes : simulated concentrations in shellfish fresh would become directly comparable with usual measurements of the monitoring networks. Our model points out the important impact of Loire river loads on the primary production on the western and southern Brittany. This result is crucial for administrations in charge of reducing the terrestrial loadings responsible for eutrophication, because it can delay reduction programs on small tributaries until the main input from the Loire has been significantly reduced. A question arises, about the reliability of the haline stratification in the model, because the horizontal extent of the Loire plume will be enhanced by a stronger stratification.
L'eutrophisation des milieux marins côtiers, de plus en plus importante, représente un des impacts majeurs des activités humaines sur l'environnement. Les phénomènes d'eutrophisation sont en constante augmentation ; ces dernières décennies ont vu le nombre de sites touchés augmenter de par le monde. La bande côtière bretonne est particulièrement concernée par ce phénomène. L'eutrophisation s'y manifeste de deux façons : "Des phénomènes de marée vertes, très localisées, qui sont provoqués par la croissance excessive et l'échouage de macro-algues du genre Ulva dans ces zones riches en azote ; Des blooms de phytoplancton à l'origine des phénomènes d'eaux colorées, qui peuvent aussi provoquer des interdictions de consommation de coquillages lorsque les espèces mises en jeu sont toxiques (Pseudo-Nitzschia, Alexandrium, Dinophysis). L'objectif de ce travail est multiple : il vise à mettre en évidence et à comprendre l'impact et le rôle des apports en nutriments sur la production primaire et l'eutrophisation des milieux côtiers. Ce travail a aussi pour ambition l'identification et la compréhension des causes des phénomènes d'eutrophisation et permettre ainsi d'apporter des solutions ou des pistes d'amélioration. En n, il a aussi un objectif de prévision à court terme de l'état biologique sur la zone. Pour atteindre ces objectifs, un modèle en temps réel a été mis en oeuvre. Les résultats de simulations numériques et de mesures satellitaires sont présentés sur internet : www.previmer.org. L'outil principal de ce travail est un modèle couplé physique/biogéochimie. La partie hydrodynamique est fournie par le code Mars3D (3D hydrodynamical Model for Application at Regional Scale) développé à IFREMER. Au code hydrodynamique Mars3D est couplé le modèle des cycles de l'azote, du phosphore et du silicium d'IFREMER. Le modèle couplé permet de simuler en 3 dimensions et de manière dynamique les courants, le brassage horizontal et vertical, les champs de température et de salinité, mais aussi les principaux cycles de nutriments, reproduisant ainsi les conditions déterminantes de la production primaire. La croissance des algues est modélisée, et nous permet de voir l'influence des panaches de dilution des principales rivières bretonnes sur leur croissance. Les diffcultés du modèle à correctement simuler les concentrations en phytoplancton près des zones côtières, sont probablement dues à l'utilisation d'une climatologie de concentration en matière en suspension fondée sur des données satellitaires. Tout d'abord, les pixels côtiers des images satellitaires sont entachés d'erreurs, ensuite une climatologie n'est pas capable de représenter les apports soudains des fleuves lors des crues. Cela peut expliquer l'incapacité du modèle a représenter certains blooms liés à des périodes ensoleilées et calmes. A ce modèle de base nous avons ajouté un genre spécifique de phytoplancton : le genre Pseudo-Nitzschia. Certaines espèces de Pseudo-Nitzschia sont réputées toxiques. En effet, ce phytoplancton a la capacité de synthétiser une toxine : l'acide domoïque. Cette toxine est responsable du syndrome ASP (Amnesic Shellfish Poisoning). Le modèle reproduit globalement les mêmes zones de toxicité que les mesures du REPHY, et donne des résultats encourageants. L'étude montre que la Loire influence une large partie de la bande côtière bretonne ; son panache remonte jusqu'au nord de la mer d'Iroise, et contribue pour une grande part à l'enrichissement du sud et de l'ouest de la Bretagne. Le traçage de l'azote en provenance de la Loire au sein des cycles biogéochimiques nous a permis de quantifier cet enrichissement.

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/00015/12603/9481.pdf
http://archimer.ifremer.fr/doc/00015/12603/

Éditeur(s) : HAL CCSD
Résumé : Transposable elements play a major role in the evolution of eukaryotic genomes. Knowing the distribution of transposable elements between different species within the same taxon is essential to study their dynamics and to better understand their role in the evolution of species. Given their abundance, species diversity and living environment, crustaceans are an excellent model for studying comparative genomics of retrotransposons. It is notably in the squat lobsters that the GalEa clade of Superfamily Copia was defined. We studied the distribution of two well-known LTR retrotransposons superfamilies: Gypsy and Copia, in crustaceans. By combining PCRs with degenerate primers and in silico analysis, we identified 35 families of Copia retrotransposons and 46 families of Gypsy retrotransposons in 15 and 18 species of crustaceans (mainly Malacostraca: crabs, shrimp, krill ...). These elements have different distribution and diversity in crustaceans. Gypsy elements appear relatively commonly and diverse in all species. Conversely, the Copia elements seem rare, and consequently more difficult to detect, and are largely dominated by the elements of the clade GalEa. These results suggest two different dynamic strategies for retrotransposons Gypsy (the Red Queen theory) and retrotransposons GalEa (‘domino days spreading’ branching process). In addition, GalEa elements present a great evolutionary success being widely distributed in many branches of metazoans. They are also present in certain red algae and we have also detected them in Fungi. Taking advantage of the large amount of available genomic data, we have studied the distribution of GalEa elements of Fungi, in order to compare it with the results obtained in crustaceans. In fact, they appear only in a large phylum of Ascomycetes, in Pezizomycotina, and they form a monophyletic group within the GalEa. Finally, in the Fungi, the GalEa elements are not majority among Copia retrotransposons. We have therefore initiated a new study in molluscs, to define if the results obtained in crustaceans are a feature of GalEa elements, Malacostraca or metazoans.
Les éléments transposables jouent un rôle majeur dans l’évolution des génomes eucaryotes. La connaissance de la distribution des éléments transposables entre différentes espèces au sein d’un même taxon est une condition essentielle pour étudier leur dynamique et mieux comprendre leur rôle dans l'évolution des espèces. Compte tenu de leur abondance, de leur diversité spécifique et de milieu de vie, les crustacés sont un excellent modèle pour étudier la génomique comparative des rétrotransposons. C’est notamment chez les Galathées qu’a été défini le clade GalEa des éléments de la superfamille des Copia. Nous avons étudié la distribution de deux superfamilles de rétrotransposons à LTR bien connus: les Gypsy et les Copia, au sein des crustacés. En combinant des PCRs avec amorces dégénérées et des analyses in silico, nous avons identifié 35 familles de rétrotransposons Copia et 46 familles de rétrotransposons Gypsy dans respectivement 15 et 18 espèces de crustacés (principalement des malacostracés : crabes, crevettes, krill...). Ces éléments présentent une distribution et une diversité différentes au sein des crustacés. Les éléments Gypsy apparaissent relativement fréquents et diversifiés dans toutes les espèces. A l’inverse, les éléments Copia semblent rares, donc difficilement détectables, et sont largement dominés par les éléments du clade GalEa. Ces résultats suggèrent deux stratégies différentes de dynamique pour les rétrotransposons Gypsy (théorie de la Reine Rouge) et les rétrotransposons GalEa (‘domino days spreading’ branching process). De plus, les éléments GalEa présentent un grand succès évolutif en étant largement distribués dans de nombreuses branches de métazoaires. Ils sont aussi présents chez quelques algues rouges et nous en avons également détecté chez des Fungi. Profitant des nombreuses données génomiques disponibles, nous avons donc étudié la distribution des éléments GalEa de Fungi, dans le but de comparer celle-ci aux résultats obtenus chez les crustacés. En fait, ils n’apparaissent qu’au sein d’un grand embranchement d’ascomycètes, les Pezizomycotina, et ils forment un groupe monophylétique au sein des GalEa. Enfin, chez les Fungi, les éléments GalEa ne sont pas majoritaire parmi les rétrotransposons Copia. Nous avons donc initié une nouvelle étude chez les mollusques, afin de définir si les résultats obtenus chez les crustacés sont une caractéristique des éléments GalEa, des malacostracés ou des métazoaires.
https://tel.archives-ouvertes.fr/tel-01132413

NNT : 2015PA066017
tel-01132413
https://tel.archives-ouvertes.fr/tel-01132413
https://tel.archives-ouvertes.fr/tel-01132413/document
https://tel.archives-ouvertes.fr/tel-01132413/file/these_archivage_2600252o.pdf

Éditeur(s) : HAL CCSD Royal Society of Chemistry
Résumé : International audience
LA-ICP-MS analysis of the chemical composition of biogenic carbonate has many applications in the environmental sciences but the characteristics of the material produced by the ablation process are largely unknown. To fill this gap, we have undertaken a study of the chemical and physical nature of particles produced by laser ablation of biogenic carbonates. SEM imaging suggests that laser ablation produces two distinct particle populations, one consisting of microsize particles and the other of nanosize particles. A 213 nm laser gives rise to a higher proportion of microsize particles than a 193 nm laser, probably because the 213 nm laser couples less completely with carbonate material. The microsize particles appear to form by photomechanical fracturing along lines of cleavage or weakness, rather than by hydrodynamic sputtering (as is generally observed for silicates). Chemical analysis of the carbonate particles suggests that little chemical fractionation of biogenic carbonates occurs during the ablation process or during transport to the plasma. This is supported by the constancy of the fractionation factor ([X/Ca](measured)/[X/Ca] true) during the course of an ablation of a carbonate standard. In contrast, changes in the fractionation factor during the first few seconds of ablation of the NIST 612 are observed for some elements. This difference in fractionation is likely to result from the different formation mechanisms of the microsize particles.
ISSN: 0267-9477

hal-00411933
https://hal.archives-ouvertes.fr/hal-00411933
DOI : 10.1039/b706727e

Éditeur(s) : HAL CCSD American Geophysical Union
Résumé : International audience
The hydraulic and electrical properties of pyroclastic rocks have been investigated in laboratory on a representative sampling of Montagne Pelée (Martinique, France) deposits with renewed interest in geophysical applications. This sampling covers all the lithologic units of this volcano: lava dome and lava flows, pumices from ash-and-pumice fall and flow deposits, lava blocks from block-and-ash flow and Peléean “nuées ardentes” deposits, scoriae from scoria flow deposits. The connected porosity varies over a wide range from 3 to 62%. The unconnected porosity is important only on pumices where it can reach 15%. The permeability covers more than 5 orders of magnitude, ranging from 10−16 to 35 × 10−12 m2. The higher values are obtained on lava blocks and the scoriae, even if these rocks are less porous than the pumices. The formation factor ranges from 7 to 1139. The transport properties of these rocks are slightly correlated with porosity. This indicates that these properties are not only controlled by the connected porosity. To connect the transport properties to the textural characteristics of the pore network of pyroclastic rocks, different models, based on geometrical considerations or percolation theory, were tested. The pore access radius distribution and the tortuosity control the transport properties of pyroclastic rocks. Consequently, the models (electric and hydraulic) based on the concept of percolation (e.g., the models of Katz and Thompson), apply better than the equivalent channel model of Kozeny-Carman. In addition, the difference in transport properties observed on lava blocks and pumices confirms that the mechanisms of degassing and vesiculation are different for these two types of rock.
ISSN: 2169-9313

hal-00310237
https://hal.archives-ouvertes.fr/hal-00310237
DOI : 10.1029/2006JB004385, 2007

Résumé : Aux Antilles, la faible fréquence des coronaropathies pourrait être liée à des facteurs génétiques, ethniques et/ou une distribution spécifique des facteurs de risque cardio-vasculaire (FDRCV). Les propriétés l'ANP (Atrial Natriuretic Peptide) et l'influence de certains polymorphismes de son gène, fréquents dans les populations d'ascendance Africaine pourraient également être en cause. L'analyse des dossiers de 638 patients coronariens consécutifs a mis en évidence une forte prévalence de l'hypertension artérielle et du diabète dans cette population et révélé des différences significatives dans la prévalence des FDRCV entre Afro-Caribéens (AC), Caucasiens et descendants de migrants Indiens. L'analyse angiographique de 420 patients AC a révélé que le diabète était le FDRCV le plus fortement lié à la sévérité des lésions coronaires alors l'obésité apparaissait comme un facteur protecteur. La transfection in vitro, de cellules musculaires lisses artérielles par une construction adénovirale porteuse du gène de l'ANP a entrainé une inhibition de la prolifération et de la migration cellulaire de 31 % et 25% respectivement. In vivo, cet effet s'est traduit par une réduction de 25% de la formation néotimale et de 28% du rapport intima/média dans un modèle d'hyperplasie de carotide de rat. Dans étude transversale incluant 210 sujets diabétiques AC nous avons mis en évidence une association entre le polymorphisme rs5065 (22381>C) du gène de l'ANP et l'existence d'une coronaropatbie. Dans cette étude, l'odds ratio de la présence d'une coronaropathie chez les porteurs de l'allèle mineur de cette mutation (TC/CC) était de 0,50 (0,26- 0,96; P = 0,038).
In Guadeloupe and Martinique, the low frequency ofcoronary artery disease (CAD) could be related to genetic or ethniefactors and/or specifie distribution ofcardiovascular risk factors (CRFs). Atrial Natriuretic Peptide (ANP) properties and influence of sorne of ANP gene polymorphism that are frequent in populations of African descent could also be involved in CAD occurrence. We retrospectively studied 638 consecutive patients with documented CAO and found a high prevalence of hypertension and diabetes in this population. This study also demonstrated significant differences in the prevalence of CRFs between Afro-Caribbean (AC), Caucasians and Indians migrants. The angiographie analysis of420 patients revealed that in AC, diabetes emerged as the strongest CFR related to the severity ofcoronary lesions while obesity appeared as a protective factor. After transfection by an adenoviral construct carrying the ANP gene, vascular smooth muscle cell proliferation stimulated by 10% fetal calf serum was reduced by 31% and migration by 25%. In vivo, in rat carotid artery model ofvascular injury, neointima formation and intima/media ratio was reduced by 25% and 28% respectively. In a cross-sectional study inc1uding 210 AC diabetics we found an association between rs5065 (22381> C) polymorpbism and the presence of coronary artery disease suggesting that the minor allele could have a protective effect against CAD. The odds ratio for the presence ofCAD in carriers ofthe minor allele ofthis mutation (TC / CC) was 0.50 (0.26-0.96, P = 0.038).

http://www.theses.fr/2012AGUY0553/document