Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The full numerical simulation of turbulent flows in the context of industrial applications remains a very challenging problem. One of the difficulties is the presence of a large number of interacting scales of different orders of magnitude, ranging from the macroscopic scale to the Kolmogorov dissipation scale. In order to better understand and simulate these interactions, new algorithms of incremental type have recently been introduced, stemming from the theory of infinite-dimensional dynamical systems (see, e.g., the algorithms of Foias, Jolly et al. (1988), Foias, Manley and Temam (1988), Laminie et al. (1993, 1994), Marion and Temam (1989, 1990), and Temam (1990)). These algorithms are based on decompositions of the unknown functions into a large- and a small-scale component, one of the underlying ideas being to approximate the corresponding attractor. In the context of finite element methods, the decomposition of a solution into small- and large-scale components appears when we consider hierarchical bases (Yserentant, 1986; Zienkiewicz et al., 1982). In the present article we derive several estimates of the size of the structures for the linear and nonlinear terms which correspond to interactions of different hierarchical components of the velocity field, and also their time variation. The one-step time variation of these terms can be smaller than the expected accuracy of the computation. Using this remark, we implement an adaptive spatial and temporal multilevel algorithm which treats differently the small- and large-scale components of the flow. We derive several a priori estimates in order to study the perturbation introduced into the approximated equations. All the interaction terms between small- and large-scale structures are frozen during several time steps. Finally, we implement the multilevel method in order to simulate a bidimensional flow described by the Burgers equations. We perform a parametric study of the procedure and its efficiency. The gain in CPU time is significant and the trajectories computed by our multi-scale method remain close to the trajectories obtained with the classical Galerkin method.
ISSN: 0168-9274

hal-00730710
https://hal.archives-ouvertes.fr/hal-00730710

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Genetics and molecular biology have been instrumental for a better understanding of heritable defects causing human infertility over the past decades. More recently, the field of reproductive biology has harnessed genome biological approaches to gain insight into molecular processes underlying normal and pathological gametogenesis and gamete function. We are currently witnessing yet another quantum leap in our ability to monitor the flow of information from the genome via the transcriptome to the proteome: tiling arrays that cover both strands of a given target genome and RNA-Seq, a method based on ultra-high throughput DNA sequencing, enable us to study noncoding and protein-coding transcripts with unprecedented precision and depth at a reasonable cost. These technologies have spawned a thriving discipline within the bioinformatics field that employs information technology for managing and interpreting biological high-throughput data. This review outlines database projects and online analysis tools useful for life scientists in general and discusses in detail selected projects that have specifically been developed for researchers and clinicians in the field of reproductive biology. This article is part of a Special Issue entitled: Molecular Genetics of Human Reproductive Failure.
ISSN: 0006-3002

hal-00877444
https://hal.archives-ouvertes.fr/hal-00877444
DOI : 10.1016/j.bbadis.2012.05.018
PUBMED : 22687534

Éditeur(s) : HAL CCSD Wiley
Résumé : 1. Functional traits provide insight into a variety of ecological questions, yet the optimal sampling method to estimate the community-level distribution of plant functional trait values remains a subject of debate, especially in species-rich forests. 2. We present a simulation analysis of the trait distribution of a set of nine completely sampled permanent plots in the lowland rain forests of French Guiana. 3. Increased sampling intensity consistently improved accuracy in estimating community-weighted means and variances of functional trait values, whereas there was substantial variation among functional traits and minor differences among sampling strategies. 4. Thus, investment in intensified sampling yields a greater improvement in the accuracy of estimation than does an equivalent investment in sampling design complication. 5. Notably, 'taxon-free' strategies frequently had greater accuracy than did abundance-based strategies, which had the additional cost of requiring botanical surveys. 6. We conclude that there is no substitute for extensive field sampling to accurately characterize the distribution of functional trait values in species-rich forests.
ISSN: 0269-8463

hal-01536541
https://hal.archives-ouvertes.fr/hal-01536541
PRODINRA : 343202
DOI : 10.1111/1365-2435.12433

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Let C be a smooth curve over a Galois ring R. Let f be a function over C, and Ψ be an additive character of order p^l over R; in this paper we study the exponential sums associated to f and Ψ over C, and their L-functions. We show the rationality of the L-functions in a more general setting, then in the case of curves we express them as products of L-functions associated to polynomials over the affine line, each factor coming from a singularity of f. Finally we show that in the case of Morse functions (i.e. having only simple singularities), the degree of the L-functions are, up to sign, the same as in the case of finite fields, yielding very similar bounds for exponential sums.
ISSN: 1071-5797

hal-00551470
https://hal.archives-ouvertes.fr/hal-00551470
https://hal.archives-ouvertes.fr/hal-00551470/document
https://hal.archives-ouvertes.fr/hal-00551470/file/Charlefinal.pdf
DOI : 10.1016/j.ffa.2009.01.001

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
Anisotropy of low-field magnetic susceptibility (AMS) of basaltic lava flows can give some clues about post-emplacement tilting occurring in volcanic sequences. Such a study has been carried out on a sequence of 19 successive lava flows from Kerguelen Archipelago. Surprisingly, two different patterns were observed. The first one - herein called normal fabric - is consistent with the lava-flow direction inferred from geological observations, whereas the second one observed for about 70 per cent of the analysed samples - herein called abnormal fabric - appears to be unrelated to the shear history of the lava flows during their emplacements. These abnormal fabrics are not strictly inverse fabric but seem to have a more complex origin. The unusual nature of these abnormal fabrics has been confirmed by lattice preferred orientation of plagioclases obtained from high-resolution electron backscattered diffraction measurements. The aim of this study is to propose a physical interpretation of these fabrics. A first step in our understanding was to clearly identify the nature and the magnetic properties of the Fe-Ti oxides assemblage. Thus, we present a comprehensive rock magnetic analysis relying on low- and high-temperature thermomagnetic curves (K-T), crossover diagrams, first-order reversal curves, ore-microscopy, Mössbauer measurements and electron backscattered images. We found that in the present case the abnormal fabrics are probably linked to a mixture of prevailing single domain (SD) strongly interacting grains population and a subsidiary multidomain grains population. SD grains are identified as small magnetite crystallized within the interstitial glass in globular aggregates along the silicate framework. Then a question arises: to what extent such SD interacting grains in globular aggregates can affect the magnetic susceptibility and its anisotropy? To answer this question, we developed a physical model in which the total energy density of an SD grain with an uniaxial anisotropy is minimized. In this model, the distribution function of the direction of the magnetic interaction field is comprised between two boundary states. It is either isotropic, which formally corresponds to the thermal demagnetized state, or it is ordered, which formally corresponds to the Alternative Field demagnetized state. We show that in both cases the degree of anisotropy decreases as the interaction field increases. Thus, we conclude that the abnormal fabric encountered in this study can be simply explained by strong magnetostatic interactions that would explain the large scattering of AMS often observed in basaltic lava flows.
ISSN: 0956-540X

hal-00716449
https://hal.archives-ouvertes.fr/hal-00716449
https://hal.archives-ouvertes.fr/hal-00716449/document
https://hal.archives-ouvertes.fr/hal-00716449/file/gji-S-12-HAL.pdf
DOI : 10.1111/J.1365-246X.2012.05421.X

Éditeur(s) : HAL CCSD
Résumé : International audience
Anwendungen des infinitesimalmathematik
Oberwolfach, Germany

hal-01535427
https://hal.univ-antilles.fr/hal-01535427

Résumé : In the booming context of shrimp culture in French Caledonia, some research actions need to be considered in order (i) to make sure this production will not impact the quality and biodiversity of the coastal environment it is contingent upon (ii) for the field to highlight, based on objective bases, its good "environmental image", for an efficient commercialization of its products. In the framework of the MOM project, a number of actions have been carried out: Action 1: A bibliographical synthesis of the impact of shrimp culture on coastal environment has been conducted, taking into account the works carried out throughout the world and in French Caledonia in order to draw the main issues the Territory will have to deal with. It seems necessary to start with an assessment of the future and the impact of the effluents on the coastal environment. Action 2: With this aim in mind, one or more indicators, among the lagoon's environmental variables, of the influence of the farms' rejects on the coastal environment, have been searched for. The first results are presented in this report. Action 3: In parallel, a long-term program taking into account the different aspects of the problem in its entirety and complexity has been defined in relation with our partners in French Caledonia. With this aim in mind, a symposium entitled "Ecosystems and shrimp culture", organised by the Ifremer in French Caledonia, with the support of the IRD, was held in Nouméa from June 22nd to June 24th, 2005. This symposium enabled the drawing out of the research perspective on the benthos, on the functioning of the lagoon ecosystem, and on the evolution of the mangrove swamps subjected to organic matter inflows from farms.
Dans un contexte d'essor de la filière crevette de Nouvelle Calédonie, des actions de recherche doivent être envisagées (i) pour assurer que cette production n'hypothéquera pas la qualité de l'environnement littoral et sa biodiversité dont elle dépend et (ii) pour que la filière puisse mettre en avant, sur des bases objectives, son image «environnementalement correcte» garante de la bonne commercialisation de son produit. Dans le cadre de ce projet MOM, plusieurs actions ont été menées : Action 1 : Une synthèse bibliographique de l'impact de l'aquaculture de crevettes sur l'environnement littoral a été réalisée en prenant en compte les travaux conduits à travers le monde et en Nouvelle-Calédonie afin de dégager les principales problématiques concernant le Territoire. Il apparaît nécessaire comme première priorité d'être capable d'évaluer le devenir et l'impact des effluents sur l'environnement littoral. Action 2 : A ce titre, un travail de recherche d'un ou de plusieurs indicateurs, parmi les variables environnementales du lagon, de l'influence des rejets aquacoles sur l'environnement littoral a été mené. Les premiers résultats sont présentés dans ce rapport. Action 3 : Parallèlement, il a été défini en relation avec nos partenaires présents en Nouvelle-Calédonie un programme pluriannuel prenant en compte les différents aspects du problème dans sa globalité et sa complexité. Pour cela, un séminaire intitulé « Écosystèmes et crevetticulture » organisé par l'Ifremer en Nouvelle-Calédonie avec le soutien de l'IRD s'est tenu à Nouméa du 22 au 24 juin 2005. Ce séminaire a permis d'élaborer des perspectives de recherche sur le benthos, sur le fonctionnement de l'écosystème lagon et sur l'évolution des mangroves soumis à des apports de matière organique issus des élevages.

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/2006/rapport-6593.pdf
http://archimer.ifremer.fr/doc/00000/6593/

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
To understand the deep cycle of water, upper mantle water content and distribution between nominally anhydrous minerals (NAMs) and hydrous minerals (e.g., amphibole) must be constrained. We need then to understand H behaviour during mantle melting and metasomatism. Major, minor and trace element compositions including water contents were obtained on ten xenoliths of spinel-bearing peridotites from the Ray Pic locality, in the Southern part of the Massif Central (France). The sample suite investigated here is composed of rather fertile lherzolites (89.4 ≤ Fo ≤ 90.8%; 11.3 ≤ cr# in spinel ≤ 21.1%; 0.942 ≤ [Yb]cpx ≤ 1.90 ppm; cpx: clinopyroxene), which can be best explained by batch melting, with degree of melting between 3 and 10%. These xenoliths contain up to 8% modal amphibole. Three groups are defined as a function of the amphibole modal abundance (above or below 1%) and equilibrium temperature (above or below 1000 °C). Results show no clear positive correlation between modal metasomatism (amphibole) and incompatible element enrichment in cpx. Trace element compositions in cpx show strong enrichments of the most incompatible elements (e.g., (La/Sm)PM as high as 15.7; PM: normalised to primitive mantle values), but strong negative anomalies of the high field strength elements (e.g., (Th/Nb)PM as high as ~ 680). Such trace element fractionations are usually ascribed to the so-called carbonatitic metasomatism involving the percolation of small volume melts which are enriched in volatiles. The hydrogen concentrations in cpx range from 203 to 330 ppm wt. H2O, in orthopyroxene from 66 to 160 ppm wt. H2O and in olivine from 2 to 6 ppm wt. H2O. These values are within the common concentration range of other spinel-bearing peridotites. Amphiboles contain 1.9 ± 0.5 wt.% of H2O.The effect of metasomatism on water abundances in NAMs is not straightforward. Hydrous metasomatism (i.e., leading to the crystallisation of OH-bearing amphibole) has no effect on the water content of the co-existing NAMs. This suggests thus that the occurrence of hydrous minerals, such as amphibole, does not systematically imply that the coexisting NAMs are water-rich (saturated). Further, the percolation of volatile-rich small volume melts, which is fingerprinted by the strong enrichment of the incompatible elements, has also no clear effect on the water content of the NAMs. These data are thus difficult to reconcile with the admitted highly incompatible behaviour of H in upper mantle minerals.
ISSN: 0024-4937

hal-01278062
https://hal.archives-ouvertes.fr/hal-01278062
DOI : 10.1016/j.lithos.2015.08.013

Éditeur(s) : HAL CCSD
Résumé : For a decade, distance-based methods have been largely employed and improved in the field of spatial economics. Such tools are very powerful to evaluate accurately the spatial distribution of plants or retail stores for example (Duranton and Overman, 2008; Jensen and Michel, 2011). In the present paper, we introduce a new statistic measure based on distances to evaluate the spatial concentration of economic activities. As far as we know, the m function is the first relative density function proposed in the economic literature. This tool completes the typology of distance-based methods recently drawn up by Marcon and Puech (2014). By working on several theoretical and empirical examples, we prove the advantages and the limits of the m function to gauge the spatial structures in spatial economics.
https://hal.archives-ouvertes.fr/hal-01082178

hal-01082178
https://hal.archives-ouvertes.fr/hal-01082178
https://hal.archives-ouvertes.fr/hal-01082178/document

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
A major requirement for malaria elimination is the development of transmission-blocking interventions. In vitro transmission-blocking bioassays currently mostly rely on the use of very few Plasmodium falciparum reference laboratory strains isolated decades ago. To fill a piece of the gap between laboratory experimental models and natural systems, the purpose of this work was to determine if culture-adapted field isolates of P. falciparum are suitable for in vitro transmission-blocking bioassays targeting functional maturity of male gametocytes: exflagellation. Plasmodium falciparum isolates were adapted to in vitro culture before being used for in vitro gametocyte production. Maturation was assessed by microscopic observation of gametocyte morphology over time of culture and the functional viability of male gametocytes was assessed by microscopic counting of exflagellating gametocytes. Suitability for in vitro exflagellation-blocking bioassays was determined using dihydroartemisinin and methylene blue. In vitro gametocyte production was achieved using two isolates from French Guiana and two isolates from Cambodia. Functional maturity of male gametocytes was assessed by exflagellation observations and all four isolates could be used in exflagellation-blocking bioassays with adequate response to methylene blue and dihydroartemisinin. This work shows that in vitro culture-adapted P. falciparum field isolates of different genetic background, from South America and Southeast Asia, can successfully be used for bioassays targeting the male gametocyte to gamete transition, exflagellation.
ISSN: 1475-2875

Droits : http://creativecommons.org/licenses/by/
pasteur-01182753
https://hal-pasteur.archives-ouvertes.fr/pasteur-01182753
https://hal-pasteur.archives-ouvertes.fr/pasteur-01182753/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-01182753/file/LeBas%20et%202015%20version%20publie%20%281%29.pdf
DOI : 10.1186/s12936-015-0752-x

Éditeur(s) : HAL CCSD Royal Society, The
Résumé : Plant leaf litter generally decomposes faster as a group of different species than when individual species decompose alone, but underlyingmechanisms of these diversity effects remain poorly understood. Because resource C : N: P stoichiometry (i.e. the ratios of these key elements) exhibits strong control on consumers, we supposed that stoichiometric dissimilarity of litter mixtures (i.e. the divergence in C : N: P ratios among species) improves resource complementarity to decomposers leading to faster mixture decomposition. We tested this hypothesis with: (i) a wide range of leaf litter mixtures of neotropical tree species varying in C : N: P dissimilarity, and (ii) a nutrient addition experiment (C, N and P) to create stoichiometric similarity. Litter mixtures decomposed in the field using two different types of litterbags allowing or preventing access to soil fauna. Litter mixture mass loss was higher than expected from species decomposing singly, especially in presence of soil fauna. With fauna, synergistic litter mixture effects increased with increasing stoichiometric dissimilarity of litter mixtures and this positive relationship disappeared with fertilizer addition. Our results indicate that litter stoichiometric dissimilarity drives mixture effects via the nutritional requirements of soil fauna. Incorporating ecological stoichiometry in biodiversity research allows refinement of the underlying mechanisms of how changing biodiversity affects ecosystem functioning.
ISSN: 0962-8452

hal-01204222
https://hal.archives-ouvertes.fr/hal-01204222
DOI : 10.1098/rspb.2014.1682
PRODINRA : 289918

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : L’Union européenne opère actuellement la seconde révision de sa politique de la pêche depuis la création de celle-ci, en 1970. Instituée pour développer la pêche maritime et garantir un revenu aux pêcheurs, la politique commune de la pêche (PCP) s’est orientée progressivement vers la protection des espèces et de l’environnement marin. Pour cela, elle a sacrifié une part importante du secteur productif, mais a échoué et, avec le déclin de la pêche en Europe, les régions ultrapériphériques de la Caraïbe (RUP-C) ont gagné en importance relative dans ce domaine. Elles représentent aujourd’hui près de 30 % de la flotte nationale et les fondements malthusiens de la PCP ne sont plus adaptés à leurs caractéristiques : ressources halieutiques, développement économique, emplois, sécurité des approvisionnements alimentaires, etc. La réforme actuellement en cours, qui devrait aboutir avant 2012, offre peut-être une alternative aux RUP-C permettant la mise en œuvre des mesures spécifiques en application de l’article 349 du Traité sur le Fonctionnement de l’Union européenne.
The European Union currently operates the second reform of its Common Fisheries Policy since its creation in 1970. Established to develop the fisheries and provide incomes for fishermen, the Common Fisheries Policy (CFP) was directed gradually towards the protection of the species and the marine environment. To do this, it sacrificed a large part of the productive sector, but failed, and with the decline of fisheries in Europe, the outermost regions of the Caribbean gained relative importance in this field. They now account for nearly 30% of the national fleet and the Malthusians bases of the CFP are not suited any more to their characteristics: fisheries resources, economic development, jobs, security of food supply, etc. The ongoing reform, which should be in force before 2012, may offer an alternative to the outermost regions of the Caribbean for the implementation of specific measures under Article 349 of the Treaty on the Functioning of the European Union.
Caraïbes
Europe

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.4356
http://journals.openedition.org/etudescaribeennes/4356

Éditeur(s) : HAL CCSD AGU and the Geochemical Society
Résumé : International audience
We propose a new thermomechanical numerical model of mid-ocean ridge accretion aimed at investigating asymmetric spreading rates, diverse configurations of lens and sill magma injections, crystallization and depth, and on- and off-axis patterns of hydrothermal cooling. The numerical algorithm iteratively resolves temperature and motion equations until it reaches a stationary solution. The motion equation was written in a vorticity-stream function formalism, with boundary and internal conditions applied to the stream function to impose the style of magma injection. Unlike in previous models, our model does not assume an a priori shape for the temperature field, which is initiated by an initial half-space cooling according to the left and right spreading rates. Complex patterns of hydrothermal cooling are simulated by enhanced thermal diffusivity. The model succeeds in describing the dynamic and thermal effects of spreading rates, the style of magma intrusion, and the hydrothermal cooling. Accurate descriptions of these are essential to study the cooling histories of crustal rocks and geophysical observables.
ISSN: 1525-2027

hal-00413118
https://hal.archives-ouvertes.fr/hal-00413118
DOI : 10.1029/2008GC002270

Éditeur(s) : Wiley-blackwell
Résumé : 1. Abiotic and biotic variables of coastal lagoons are highly heterogeneous in both space and time, and this heterogeneity complicates the assessment of their ecological status. These variables are essential to the monitoring and preservation of these fragile ecotones and the resources and services they sustain. 2. An integrative approach for evaluating the ecological status of coastal lagoons, based on field investigations of the key parameters driving their functioning and a set of selected ecological indicators matching lagoon management information needs for societal benefits, is investigated. Consistency in lagoon status evaluation from multiple and different variables was estimated, through a case study comparing three adjacent yet contrasting French Mediterranean shallow water lagoons. 3. French Mediterranean shallow water lagoons are used to demonstrate the potential of such an approach and to underline the need for a multi-faceted framework, for correctly evaluating lagoon status, and underlining the need for high-frequency lagoon monitoring to avoid errors in status assessment and resulting management plans. 4. Based on the results, a continuous monitoring system is proposed that would record high frequency biotic and abiotic data in the lagoons. The use of such an ad hoc observatory system, based on appropriate diagnostic indicators and risk estimators would simplify interactions between scientists and managers and would improve the efficiency of their analyses. 5. A lagoon management plan based on a holistic approach is proposed to help scientists and local managers to reach a consensus about the set of ecological indicators to monitor in the lagoons needed to assess their global health status in accordance with both conservation and/or societal needs. Copyright (c) 2011 John Wiley & Sons, Ltd.
Aquatic Conservation-marine And Freshwater Ecosystems (1052-7613) (Wiley-blackwell), 2011-11 , Vol. 21 , N. 7 , P. 728-742

Droits : 2011 John Wiley & Sons, Ltd.
http://archimer.ifremer.fr/doc/00056/16702/14202.pdf
DOI:10.1002/aqc.1231
http://archimer.ifremer.fr/doc/00056/16702/

Éditeur(s) : HAL CCSD Springer Verlag (Germany) Springer Verlag
Résumé : Production rates in horizontal shale gas wells display declines that are controlled by the low permeability and the intrinsic heterogeneity of the shale matrix. We present an original multi-continuum approach that yields a physical model able to reproduce the complexity of the decreasing gas rates. The model describes the dynamics of gas rate as function of the physical reservoir parameters and geometry, while the shale matrix heterogeneity is accounted for by a stochastic description of transmissivity field. From the 3D (Dimensional) problem setting, including the heterogeneous shale matrix, the fractures generated by the hydrofracking operations, as well as the production well characteristics, we establish an effective upscaled 1D model for the gas pressures in fracture and matrix as well as the volumetric flux. We analyse the decline curves behaviour, and we identify the time scales that characterize the dynamics of the gas rate decline using explicit analytical Laplace space solutions of the upscaled process model. Asymptotically, the flux curves decrease exponentially, while in an intermediate regime we find a power-law behaviour, in which the flux scales with a power law in time as (t^{-beta }), where (beta ) reflects the medium heterogeneity. We use this solution to fit a set of real data displaying distinctly different decline trends and study the sensitivity of the model to the reservoir parameters in order to identify their respective controls at the different stages of the decline curve dynamics. Results indicate that the initial value of the gas rate is determined by the transmissivity of the fractures and the initial pressure of the gas in the shale matrix. The latter causes mainly a shift in the entire decline curve. The early time of decline curve shape is primarily controlled by the fracture properties (compressibility and transmissivity). During the main part of the economically valuable production times, i.e. before the production rate drops exponentially, the decline curve is strongly controlled by the properties of the shale rocks including their heterogeneity, which is modelled by two parameters describing the non-Fickian pressure diffusion effects in a stochastic framework.
ISSN: 0169-3913

hal-01217247
https://hal.archives-ouvertes.fr/hal-01217247
DOI : 10.1007/s11242-015-0504-y

Éditeur(s) : HAL CCSD
Résumé : National audience
Endometriosis is a common gynecological estrogen-dependent disorder, affecting more than 10 % of women in reproductive age. This disease results in chronic pelvic pain and infertility and is characterized by the presence of functional endometrial tissue outside of uterine cavity. To date, the diagnosis of endometriosis takes many years because of the lack of non-invasive diagnostic tools. Interestingly, "Omics" technologies demonstrated their relevance for the search, identification and characterization of potential disease biomarkers with significant achievements in many areas in the field of human health. Use a panel of Omics approaches seems to be a good way to improve our knowledge about endometriosis. Despite several studies on the subject, the potential biomarkers obtained are still not used in the clinical practice, as it calls for large-scale validation. Combined approaches based on strong interdisciplinary collaborations should improve our knowledge of endometriosis, and allow the identification of specific predictive markers, thus leading to the development of therapeutic solutions for a non-invasive and early diagnosis of this debilitating disease. Copyright © 2017 John Libbey Eurotext.
Medecine Therapeutique Medecine de la Reproduction, Gynecologie et Endocrinologie

hal-01467551
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01467551
DOI : 10.1684/mte.2016.0632

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
Ecosystems are commonly affected by natural, episodic disturbances that can abruptly and drastically alter communities. Although it has been shown that resilient ecosystems can eventually recover to pre-disturbed states, the extent to which communities in early stages of recovery could be affected by multiple anthropogenic stressors is poorly understood. Pervasive and rising anthropogenic stressors in coastal marine systems that could interactively affect the recovery of these systems following natural disturbances include high sedimentation, nutrient enrichment, and overfishing. Using a 6-month field experiment, we examined the effects of all combinations of these three stressors on key functional groups in the benthic community growing on simulated, post-disturbance reef patches within a system recovering from large-scale natural disturbances (corallivorous seastar outbreak and cyclone). Our study revealed that sedimentation, nutrient enrichment, and overfishing (simulated using exclusion cages) interactively affected coral survival and algal growth, with taxon-specific effects at multiple scales. First, our treatments affected corals and algae differently, with sedimentation being more detrimental to macroalgal growth but less detrimental to coral (Porites rus) survival in caged plots, driving significant interactions between sedimentation and caging for both taxa. We also observed distinct responses between coral species and between algal functional groups, with the most extensive responses from algal turf biomass, for which sedimentation suppressed the synergistic (positive) combined effect of nutrient enrichment and caging. Our findings suggest that different combinations of ubiquitous anthropogenic stressors, related to either sea- or land-based activities, interactively influence community recovery from disturbance and may alter species compositions in the resulting community. Our findings further suggest that anthropogenic stressors could promote further degradation of coral reefs following natural disturbances by inhibiting recovery to coral-dominated states that provide vital ecosystem services to coastal populations worldwide.
ISSN: 0722-4028

hal-01430977
https://hal-univ-perp.archives-ouvertes.fr/hal-01430977
DOI : 10.1007/s00338-016-1489-x

Éditeur(s) : HAL CCSD American Chemical Society
Résumé : International audience
Childhood absence epilepsy is a prototypic form of generalized nonconvulsive epilepsy characterized by short impairments of consciousness concomitant with synchronous and bilateral spike-and-wave discharges in the electroencephalogram. For scientists in this field, the BS/Orl and BR/Orl mouse lines, derived from a genetic selection, constitute an original mouse model "in mirror" of absence epilepsy. The potential of MALDI imaging mass spectrometry (IMS) for the discovery of potential biomarkers is increasingly recognized. Interestingly, statistical analysis tools specifically adapted to IMS data sets and methods for the identification of detected proteins play an essential role. In this study, a new cross-classification comparative design using a combined discrete wavelet transformation-support vector machine classification was developed to discriminate spectra of brain sections of BS/Orl and BR/Orl mice. Nineteen m/z ratios were thus highlighted as potential markers with very high recognition rates (87-99%). Seven of these potential markers were identified using a top-down approach, in particular a fragment of Synapsin-I. This protein is yet suspected to be involved in epilepsy. Immunohistochemistry and Western Blot experiments confirmed the differential expression of Synapsin-I observed by IMS, thus tending to validate our approach. Functional assays are being performed to confirm the involvement of Synapsin-I in the mechanisms underlying childhood absence epilepsy.
ISSN: 1535-3893

hal-00877728
https://hal.archives-ouvertes.fr/hal-00877728
DOI : 10.1021/pr3006974
PUBMED : 22994238

Éditeur(s) : HAL CCSD
Résumé : International audience
The purpose of this communication is to examinate the impact of the authority of the digital media in the field of scientific research. To communicate, to publish content and to be "recognized" in the social networking services, could be considered as equivalents to "being legitimized" in the world of research? In this context, we examine notions like that of "digital authority" over that of "scientific authority" in order to analyze the functioning and the role of the new media spaces in the world of research.
L’objectif de cette communication est de poser la question de l’impact de l’autorité de l’espace médiatique numérique dans le domaine de la recherche scientifique. Communiquer, publier des contenus et être « reconnu » dans les médias socio-professionnels numériques pourrait-il être considéré comme «se légitimer » dans le monde de la recherche? Dans ce contexte, nous examinons des notions comme celle d’« autorité numérique » par rapport à celle d’ « autorité » scientifique afin d’analyser le fonctionnement et le rôle de ces nouveaux espaces médiatiques dans le monde de la recherche.
Les écosystèmes numériques et la démocratisation informationnelle : Intelligence collective, Développement durable, Interculturalité, Transfert de connaissances
Schoelcher, France

hal-01258180
https://hal.univ-antilles.fr/hal-01258180
https://hal.univ-antilles.fr/hal-01258180/document
https://hal.univ-antilles.fr/hal-01258180/file/Pergia%20GKOUSKOU-GIANNAKOU.pdf

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Mapping forest aboveground biomass (AGB) has become an important task, particularly for the reporting of carbon stocks and changes. AGB can be mapped using synthetic aperture radar data (SAR) or passive optical data. However, these data are insensitive to high AGB levels (>150 Mg/ha, and >300 Mg/ha for P-band), which are commonly found in tropical forests. Studies have mapped the rough variations in AGB by combining optical and environmental data at regional and global scales. Nevertheless, these maps cannot represent local variations in AGB in tropical forests. In this paper, we hypothesize that the problem of misrepresenting local variations in AGB and AGB estimation with good precision occurs because of both methodological limits (signal saturation or dilution bias) and a lack of adequate calibration data in this range of AGB values. We test this hypothesis by developing a calibrated regression model to predict variations in high AGB values (mean >300 Mg/ha) in French Guiana by a methodological approach for spatial extrapolation with data from the optical geoscience laser altimeter system (GLAS), forest inventories, radar, optics, and environmental variables for spatial inter-and extrapolation. Given their higher point count, GLAS data allow a wider coverage of AGB values. We find that the metrics from GLAS footprints are correlated with field AGB estimations (R 2 =0.54, RMSE=48.3 Mg/ha) with no bias for high values. First, predictive models, including remote-sensing, environmental variables and spatial correlation functions, allow us to obtain "wall-to-wall" AGB maps over French Guiana with an RMSE for the in situ AGB estimates of ~51 Mg/ha and R²=0.48 at a 1-km grid size. We conclude that a calibrated regression model based on GLAS with dependent environmental data can produce good AGB predictions even for high AGB values if the calibration data fit the AGB range. We also demonstrate that small temporal and spatial mismatches between field data and GLAS footprints are not a problem for regional and global calibrated regression models because field data aim to predict large and deep tendencies in AGB variations from environmental gradients and do not aim to represent high but stochastic and temporally limited variations from forest dynamics. Thus, we advocate including a greater variety of data, even if less precise and shifted, to better represent high AGB values in global models and to improve the fitting of these models for high values.
ISSN: 0303-2434

Droits : http://creativecommons.org/licenses/by/
hal-01381116
https://hal.archives-ouvertes.fr/hal-01381116
https://hal.archives-ouvertes.fr/hal-01381116/document
https://hal.archives-ouvertes.fr/hal-01381116/file/Fayad2016a.pdf
DOI : 10.1016/j.jag.2016.07.015