Éditeur(s) : Gauthier-Villars
Résumé : Since the advent of plate tectonics the active margins of the oceans have been studied according to a model whose basis is a piling up of imbrications of oceanic material units, in front of the upper plate, forming a great tectonic accretionary prism. This model is broadly the same for all the authors; it has been largely used for alpine-type or paleo-oceanic mountain chain, all around the world. The authors have directly taken part in the drillings on western and eastern Pacific active margins (Legs 60 and 67) and they have worked on the tectonics of alpine (paleo-oceanic) chains of the peri-mediterranean, peri-caribbean, and peripacific belts. They compare the geological data acumulated from these tow direct sources. The tectonic constraints constraints regime is specified and the consequences of the subduction are looked for. The notions of collison and obduction are discussed in relation to subduction and tectonics. Finally, an anlaysis of the temporal evolution of active margins and of chains, shows the necessity of thinking in terms of superimposed tectonics.
Oceanologica Acta, Special issue (0399-1784) (Gauthier-Villars), 1981

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/00246/35700/34207.pdf
http://archimer.ifremer.fr/doc/00246/35700/

Éditeur(s) : HAL CCSD Annex Publishers
Résumé : International audience
Introduction: Shark-based ecotourism is significantly developing around the world, often without appropriate management of risk. This activity involves a risk of accidental bites on divers that can be quite severe or even fatal. Objectives: To determine if ecotourism companies' liability can be engaged in the context of bites on scuba divers in presence of hand-feeding practices, supporting the legitimacy of financial compensation for the victims. Methods: We analyzed the development from the mid-eighties to 2010 of shark-based ecotourism through artificial provisioning practices in Moorea Island (French Polynesia) and more specifically the features and motivation of two bites on divers by Sicklefin Lemon sharks. Results: The specific practice of hand-feeding can be considered as a facilitating factor for accidental bites on divers, potentially involving the diving operator's responsibility. Conclusions: Our findings should support the technical work of experts that might be called in such cases.
ISSN: 2348-9804

hal-01238771
https://hal-univ-perp.archives-ouvertes.fr/hal-01238771
https://hal-univ-perp.archives-ouvertes.fr/hal-01238771/document
https://hal-univ-perp.archives-ouvertes.fr/hal-01238771/file/3502-Determining-the-Role-of-Hand-Feeding-Practices-in-Accidental-Shark-Bites-on-Scuba-Divers.pdf

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Le tourisme et les secteurs des services sont devenus le domaine privilégié des politiques de développement avec le déclin du secteur agricole dans de nombreux pays en développement et les difficultés à développer un secteur industriel compétitif. Le tourisme est donc considéré comme un des moyens importants de lutte contre la pauvreté dans les pays en développement et en particulier dans les pays les moins avancés. Toutefois, il serait illusoire de croire que le tourisme peut contribuer significativement à réduire la pauvreté sans la poursuite de politiques spécifiques centrés sur cet objectif prioritaire.
Tourism and services sectors have become the preferred area of development policies in a context of declining agricultural sector (in many developing countries) and the difficulties of developing a competitive industry. Tourism is considered an important means to fight against poverty in developing countries and in particular the least developed countries. However, it would be illusory to believe that tourism can contribute significantly to poverty reduction without further specific policies focus on this priority.

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.6514
http://journals.openedition.org/etudescaribeennes/6514

Éditeur(s) : HAL CCSD Endocrine Society
Résumé : International audience
Transcriptional regulation by the estrogen receptor-alpha(ER) has been investigated mainly in breast cancer cell lines, but estrogens such as 17 beta-estradiol (E2) exert numerous extrareproductive effects, particularly in the liver, where E2 exhibits both protective metabolic and deleterious thrombotic actions. To analyze the direct and early transcriptional effects of estrogens in the liver, we determined the E2-sensitive transcriptome and ER cistrome in mice after acute administration of E2 or placebo. These analyses revealed the early induction of genes involved in lipid metabolism, which fits with the crucial role of ER in the prevention of liver steatosis. Characterization of the chromatin state of ER binding sites (BSs) in mice expressing or not ER demonstrated that ER is not required per se for the establishment and/or maintenance of chromatin modifications at the majority of its BSs. This is presumably a consequence of a strong overlap between ER and hepatocyte nuclear factor 4 alpha BSs. In contrast, 40% of the BSs of the pioneer factor forkhead box protein a (Foxa2) were dependent upon ER expression, and ER expression also affected the distribution of nucleosomes harboring dimethylated lysine 4 of Histone H3 around Foxa2 BSs. We finally show that, in addition to a network of liver-specific transcription factors including CCAAT/enhancer-binding protein and hepatocyte nuclear factor 4 alpha, ER might be required for proper Foxa2 function in this tissue.
ISSN: 0888-8809

hal-01357623
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01357623
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01357623/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01357623/file/Changes%20in%20gene%20expression%201%20and%20Estrogen%20Receptor_accepted.pdf
DOI : 10.1210/me.2015-1311

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : The paper focuses on investigation of the importance of nature and development of tourism in protected areas. Therefore, in this context a new challenge is emerging: the need to conserve and protect bio and geo diversity, as well as the economic valorisation of these areas based mainly on tourism and leisure. At EU level, Natura 2000 protected areas have developed, implemented and cultivated the need to practice sport and recreational activities in these areas both for spending leisure time and also as stress antidote. The recreational and sporting practices that can be undertaken within the ecological network Natura 2000 sites adapted to the specificity of each protected area, in close connection with the environmental conditions. For the preservation of the natural environment should develop and maintain a close collaboration with tourism and sports associations that organize such activities in those areas.
La réflexion est centrée sur l’importance de la nature et des enjeux du développement de tourisme dans les aires protégées. Un nouveau défi émerge dans le contexte actuel où il s'agit de concilier le besoin de conserver et de protéger la géodiversité et la biodiversité avec la valorisation économique de ces espaces naturels investis par les pratiques touristiques et récréatives. Au niveau de l'Union européenne, les espaces protégés Natura 2000 ont mis en œuvre des programmes permettant de répondre à l’accueil des activités sportives et de loisirs dans ces zones, tant pour passer du temps libre que comme antidote au stress. Ces pratiques entreprises dans le réseau écologique Natura 2000 sites sont adaptés à la spécificité de chaque secteur protégé, en relation avec les conditions environnementales. Pour favoriser la conservation du cadre naturel, il est important de maintenir une étroite collaboration avec les associations touristiques et sportives qui organisent des activités dans ces zones.
Bihor
Roumanie

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.11262
http://journals.openedition.org/etudescaribeennes/11262

Éditeur(s) : HAL CCSD American College of Sports Medicine (ACSM)
Résumé : International audience
PURPOSE AND METHODS: To determine the effects of cycling on a subsequent triathlon run, nine male triathletes underwent four successive laboratory trials: 1) an incremental treadmill test, 2) an incremental cycle test, 3) 30 min of cycling followed by 5 km of running (C-R), and 4) 30 min of running followed by 5 km of running (R-R). Before and 10 min after the third and fourth trials, the triathletes underwent pulmonary function testing including spirometry and diffusing capacity testing for carbon monoxide (DL(CO)). During the C-R and R-R trials, arterialized blood samples were obtained to measure arterial oxygen pressure (PaO2). During all trials, ventilatory data were collected every minute using an automated breath-by-breath system. RESULTS: The results showed that 1) the oxygen uptake (VO2) observed during subsequent running was similar for the C-R and R-R trials; 2) the ventilatory response (VE) during the first 8 min of subsequent running was significantly greater in the C-R than in R-R trial (P < 0.05); 3) only the C-R trial induced a significant increase (P < 0.05) in residual volume (RV), functional residual capacity (FRC), and the ratio of residual volume to total lung capacity (RV/TLC); and 4) although a significant decrease (P < 0.05) in DL(CO) was noted after C-R, no difference between the two exercise trials was found for the maximal drop in PaO2. CONCLUSIONS: We concluded that 1) the C-R trial induced specific alterations in pulmonary function that may be associated with respiratory muscle fatigue and/or exercise-induced hypoxemia, and 2) the greater VE observed during the first minute of running after cycling was due to the specificity of cycling. This reinforces the necessity for triathletes to practice multi-trial training to stimulate the physiological responses experienced during the swim-cycle and the cycle-run transitions.
ISSN: 0195-9131

hal-00720412
https://hal.univ-antilles.fr/hal-00720412
https://hal.univ-antilles.fr/hal-00720412/document
https://hal.univ-antilles.fr/hal-00720412/file/Article.pdf

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
Recent reports suggest that extracellular signal-regulated kinase (ERK1) and ERK2 mitogen-activated protein kinases (MAPK) may direct specific biological functions under certain contexts. In this study, we investigated the role of early and sustained epidermal growth factor (EGF) stimulation on long-term hepatocyte differentiation and the possible role of ERK1 and ERK2 in this process. We demonstrate a long-term survival and an elevated level of differentiation up to 3 weeks. The differentiation state of hepatocytes is supported by sustained expression of aldolase B, albumin, and the detoxifying enzymes CYP1A2, 2B2, and 3A23. Similarly to freshly isolated cells, cultured hepatocytes also retain the ability to respond to 3-methylcholanthrene (3MC) and phenobarbital (PB), two known CYP inducers. In addition, we show evidence that continuous MAPK/ERK kinase (MEK) inhibition enhances the level of differentiation. Using RNA interference approaches against ERK1 and ERK2, we demonstrate that this effect requires both ERK1 and ERK2 activity, whereas the specific ERK1 knockdown promotes cell survival and the specific ERK2 knockdown regulates cell proliferation. In conclusion, we demonstrate that early and sustained EGF stimulation greatly extends long-term hepatocyte survival and differentiation, and that inhibition of the ERK1/2 MAPK pathway potentiates these pro-survival/pro-differentiation phenotypes. We clearly attest that specific ERK1 and ERK2 MAPKs determine hepatocyte survival and proliferation, respectively, whereas dual inhibition is required to stabilize a highly differentiated state.
ISSN: 0021-9541

hal-00681056
https://hal.archives-ouvertes.fr/hal-00681056
DOI : 10.1002/jcp.22742
PUBMED : 21437905

Éditeur(s) : HAL CCSD American Geophysical Union - AGU
Résumé : IODP Expedition 335 "Superfast Spreading Rate Crust 4" returned to ODP Hole 1256D with the intent of deepening this reference penetration of intact ocean crust several hundred meters into cumulate gabbros. This was the fourth cruise of the superfast campaign to understand the formation of oceanic crust accreted at fast spreading ridges, by exploiting the inverse relationship between spreading rate and the depth to low velocity zones seismically imaged at active mid-ocean zones, thought to be magma chambers. Site 1256 is located on 15-million-year-old crust formed at the East Pacific Rise during an episode of superfast ocean spreading (>200 mm/yr full rate). Three earlier cruises to Hole 1256D have drilled through the sediments, lavas and dikes and 100 m into a complex dike-gabbro transition zone. The specific objectives of IODP Expedition 335 were to: (1) test models of magmatic accretion at fast spreading ocean ridges; (2) quantify the vigor of hydrothermal cooling of the lower crust; (3) establish the geological meaning of the seismic Layer 2-3 boundary at Site 1256; and (4) estimate the contribution of lower crustal gabbros to marine magnetic anomalies. It was anticipated that even a shortened IODP Expedition could deepen Hole 1256D a significant distance (300 m) into cumulate gabbros. Operations on IODP Expedition 335 proved challenging from the outset with almost three weeks spent re-opening and securing unstable sections of the Hole. When coring commenced, the destruction of a hard-formation C9 rotary coring bit at the bottom of the hole required further remedial operations to remove junk and huge volumes of accumulated drill cuttings. Hole-cleaning operations using junk baskets returned large samples of a contact-metamorphic aureole between the sheeted dikes and a major heat source below. These large (up to 3.5 kg) irregular samples preserve magmatic, hydrothermal and structural relationships hitherto unseen because of the narrow diameter of drill core and previous poor core recovery. Including the ~60 m-thick zone of granoblastic dikes overlying the uppermost gabbro, the dike-gabbro transition zone at Site 1256 is over 170 m thick, of which more than 100 m are recrystallized granoblastic basalts. This zone records a dynamically evolving thermal boundary layer between the principally hydrothermal domain of the upper crust and a deeper zone of intrusive magmatism. The recovered samples document a sequence of evolving geological conditions and the intimate coupling between temporally and spatially intercalated intrusive, hydrothermal, contact-metamorphic, partial melting and retrogressive processes. Despite the operational challenges, we achieved a minor depth advance to 1522 m, but this was insufficient penetration to complete any of the primary objectives. However, Hole 1256D has been thoroughly cleared of junk and drill cuttings that have hampered operations during this and previous Expeditions. At the end of Expedition 335, we briefly resumed coring and stabilized problematic intervals with cement. Hole 1256D is open to its full depth and ready for further deepening in the near future.
InterRidge News

hal-00688821
https://hal.archives-ouvertes.fr/hal-00688821

Éditeur(s) : Edp Sciences S A
Résumé : Moored FADs (MFADs) have been a key area for development in Guadeloupe (Lesser Antilles) since the late 1980's. The main objectives underpinning the development of MFADs were to (i) reduce fishing pressure on coastal fishing resources; (ii) boost fishermen's incomes; and (iii) increase local consumption of locally generated fishery products as a proportion of overall consumption. This paper gives an overview of the current structure of Guadeloupe's fishing fleet and fisheries, with a specific focus on MFAD fleets in a relatively unstructured environment with regard to regulation, and so how these fleets operate in a context of unrestricted development of private MFADs. In addressing the following key issues, this paper aims to: assess the economic performance of fleets operating on MFADs, understand why the MFAD fishing activity has not developed more than it has, and suggest how better MFAD management could improve the situation. Socio-economic information on a trip and fleet level basis were collected and stored on a fisheries information system to analyse the relative attractiveness of MFAD fishing and assess the overall economic performance of MFAD fleets as compared to other non-MFAD fleets. Non-monetary variables were also tested to explain the degree of dependence on MFADs. In 2008, economic returns from FADs were relatively low, both in terms of wages for the crews and in terms of profit for vessel owners. Earnings were higher than coastal fishing activities, but seem to have been very sensitive to the indicators used in our analysis. MFADs are expected to become much more attractive as a result of MFAD regulation, especially through the establishment of collective MFADs.
Aquatic Living Resources (0990-7440) (Edp Sciences S A), 2013-01 , Vol. 26 , N. 1 , P. 97-105

Droits : EDP Sciences, IFREMER, IRD 2013
http://archimer.ifremer.fr/doc/00137/24836/22914.pdf
DOI:10.1051/alr/20013044
http://archimer.ifremer.fr/doc/00137/24836/

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
BACKGROUND:In French Guiana, a French overseas territory in South America, 6 to 10 thousands undocumented persons work illegally in gold mining sites in the Amazonian forest. Precarious life conditions lead to poor health but few data exist on the health status of illegal gold miners in French Guiana. The objective of this article was to describe the sociodemographic and health status of this vulnerable population.METHOD:A prospective cross-sectional survey was conducted in 2015 on gold mine supply sites at the border between French Guiana and Suriname. Health status was assessed through medical examination, past medical history, haemoglobin concentration, and HIV and malaria testing. A questionnaire was used to collect data about the migration itinerary and life conditions on mining sites.RESULTS:Among the 421 adults included in the study, 93.8% (395/421) were Brazilian, mainly from Maranhão (55.7%, 220/395), the poorest Brazilian state. The sex ratio was 2.4. Overall, 48% of persons never went to school or beyond the primary level. The median time spent in gold mining was quite long (10 years), with a high turn-over. One third of the surveyed population (37.1%, 156/421) had high blood pressure, and only two had a medical follow-up. Most persons had experienced malaria (89.3%, 376/421). They declared frequent arboviroses and digestive disorders. Active leishmaniasis was observed in 8.3% of gold miners. Among women, 28.5% were anemic. Concerning HIV, 36.6% (154/421) of persons, mainly men, never got tested before and 6 were tested positive, which represented an HIV prevalence of 1.43% (95%CI =0.29-2.5).CONCLUSION:These findings support the hypothesis that mining in remote areas is linked to several specific illnesses. Theoretically, gold miners would be presumed to start their economical migration to French Guiana as a healthy group. However, their strenuous working and living conditions there lead to poor health caused by infectious and non infectious diseases. This description of their health status is precious for health policy planners in French Guiana given the importance of controlling communicable disease, and the severity and range of specific illnesses acquired by this neglected population.TRIAL REGISTRATION:Clinical trial registration PRS N° NCT02903706 . Retrospectively registered 09/13/2016.
ISSN: 1471-2458

inserm-01566314
http://www.hal.inserm.fr/inserm-01566314
http://www.hal.inserm.fr/inserm-01566314/document
http://www.hal.inserm.fr/inserm-01566314/file/2017%2C%20Douine%20-%20Illegal%20gold%20miners%20in%20French%20Guiana.pdf
DOI : 10.1016/S0140-6736(10)62169-1

Éditeur(s) : HAL CCSD Institut de Géographie Alpine
Résumé : International audience
The international symposium on «Urban Growth and Natural Hazards, in particular in Developing Countries» was held in the University Blaise Pascal, Clermont-Ferrand (France) on December 2 and 3, 1994. This meeting brought together about 70 research people, Ph.D. students, and professionals from France and 12 countries, representing universities, research agencies, as well as government and private companies. The symposium aimed to gather specialized people who are engaged and acting in programmes on hazard appraisal, risk prevention and urban management in city environment. These people aimed to compare experiences acquired in two different fields: on the one hand urban growth and its consequences, and on the other hand, natural hazards and effects, in particular in Developing Countries.Half-way through the International Decade for Natural Hazard Disaster Reduction, we strove to reconcile two points of view usually distincts: nature-oriented research and society-oriented research on hazards. These convergent approaches should merge, not only to improve knowledge of natural hazards and risks, but also to cope with hazard and risk situation on a day-basis in a city. We also choose to study both approaches in Developing Countries (DC) because most of the large cities of the world already are or will be located there in near future. In addition, city location in DC coincides with tropical areas where natural hazards are most frequent threats to life, in particular in mountains, on seashores, and on active convergent plate margins. We stress the fact that the 3 following topics are often lacking in studies which have been carried out on natural hazard appraisal and management. 1) How should we include social and economical factors, and particularly a sound analysis of vulnerability of people and values at risk ? 2) How should we cope with hazard management in large cities of Developing Countries ? 3) What is the specific task of research people in hazard case studies engaged in urban environment and management?Three themes correspond to the three sessions of the symposium. (1) Natural hazards and environmental factors : inventory, diagnostic and classification, (2) Vulnerability of urban society and environment : concepts, approaches, and classification, (3) Tools for urban risk prevention and risk management in case of crisis and catastrophes.
Ce numéro de la Revue de Géographie Alpine reprend une dizaine parmi les 41 contributions exposées par des chercheurs français et étrangers lors du colloque international « Croissance urbaine et risques naturels dans les pays en développement » qui s'est déroulé à l'Université Blaise Pascal, Clermont-Ferrand, les 2 et 3 décembre 1994. L'objectif général du colloque était de rassembler les diverses compétences existant en France et à l'étranger dans le domaine de l'évaluation et de la gestion des risques naturels et de confronter les expériences acquises à l'interface entre les villes en croissance et le champ d'action des phénomènes naturels créateurs de risques. Le colloque a donc réuni des chercheurs, des doctorants et des praticiens français et leurs collègues étrangers chargés de prévention, de gestion des risques naturels et de gestion urbaine, principalement dans les grandes villes des pays en développement (P.E.D.).Parvenus à mi-chemin de la Décennie Internationale pour la Prévention des Catastrophes Naturelles, nous avons porté des regards croisés sur les approches naturalistes et sociologiques des risques naturels. Il est maintenant nécessaire de faire converger ces approches, non seulement dans la connaissance des menaces et des risques, mais dans la gestion du risque quotidien en milieu urbain. Nous avons concentré ces approches dans les pays en développement ; en effet, le site de leurs grandes villes coïncide souvent avec le champ d'action des phénomènes naturels générateurs de risques, notamment dans la zone intertropicale et en particulier dans les marges continent ales actives (par exemple autour du Pacifique).Nous avons porté l'accent sur 3 points principaux, qui semblent en partie faire défaut dans les études et les méthodes actuellement mises en oeuvre dans la gestion des risques naturels : 1) comment prendre en compte les aspects socio-économiques, en particulier les types d'analyse des vulnérabilités ? 2) comment aborder la gestion des risques en milieu urbain dans les P.E.D. ? 3) quel rôle doit jouer le chercheur en Sciences de l'Homme, de la Société et de la Terre dans les analyses, les expertises consacrées aux risques et surtout dans leur gestion globale, à la charnière des sociétés citadines précaires et des milieux « naturels » contraignants ?Les contributions ont été regroupées, exposées et discutées lors du colloque sous forme de 3 thèmes. (1) Les phénomènes naturels créateurs de dommages (= menaces) : diagnostic, inventaire et typologie, (2) Les vulnérabilités des sociétés et des espaces urbanisés : concepts, typologie et modes d'analyse, (3) Les outils d'aide à la prévention et à la gestion du risque en milieu urbain.
Colloque international : "Croissance urbaine et risques naturels dans les pays en développement"
Clermont-Ferrand, Université Blaise Pascal, France

ISBN : 0035-1121
hal-01165252
https://hal.archives-ouvertes.fr/hal-01165252

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Aim of the study: A knowledge attitude and practice study centred on leishmaniasis and its treatment was performed among the Chayahuita, an Amazonian Peruvian ethnic group living in an endemic area. This study documents traditional Chayahuita plant's use and disease concepts. Also, activty of some medicinal plants used by the Chayahuita is highlighted and discussed. Materials and methods: Ninety-three Chayahuita people were interviewed, following a semi-structured questionnaire focussed on disease knowledge and perception, personal attitude and healing practices. Simultaneously, a collection of plants was performed in different ecotopes, in order to make an extensive inventory of the pharmacopoeia. Results: For the Chayahuita, cutaneous (CL) and muco-cutaneous leishmaniasis (MCL) are considered as diseases of their own, with specific names, aetiologies, mode of transmission. Regarding CL, Chayahuita people consider that the humid characteristic of the skin ulcer is a discriminative fact orienting the diagnostic forTa'ta' (leishmaniasis). Forty-six different species were designated useful against LC and /or MCL (29 species by means of the questionnaire and 27 species when collecting in different ecotopes). Thirty-seven extracts corresponding to 31 species used medicinally were screened in vitro against Leishmania amnzonensis axenic amastigotes, assessing their viability by the reduction of tetrazolium salt (MTT). Six species displayed a good activity ( 10 μg/ml < IC50 < 20 μg/ml): an undetermined hemi-epiphytic Clusiaceae, Cyhianthus anthuriophyllus Pipoly (Myrsinaceae), two Piper, Piper sanguineispicum Trel., and Piper loretoanum Trel. (Piperaceae), Desmodium axillare Sw. DC. (Fabaceae), and Clibadium sylvestre (Aubl.) Baill. (Asteraceae). Conclusion: Perception of leishmaniasis, attitude, treatments and diet prohibitions still largely reflects traditional Chayahuita cosmovision, even if some tentative of bio-medical re-interpretation is arising.
ISSN: 0378-8741

hal-01087667
https://hal-agroparistech.archives-ouvertes.fr/hal-01087667
DOI : 10.1016/j.jep.2009.07.015

Éditeur(s) : HAL CCSD Ecological Society of America
Résumé : Line transect surveys are widely used in neotropical rainforests to estimate the population abundance of medium- and large-sized vertebrates. The use of indices such as Encounter Rate has been criticized because the probability of animal detection may fluctuate due to the heterogeneity of environmental conditions among sites. In addition, the morphological and behavioral characteristics (biological traits) of species affect their detectability. In this study, we compared the extent to which environmental conditions and species' biological traits bias abundance estimates in terra firme rainforests in French Guiana. The selected environmental conditions included both physical conditions and forest structure covariates, while the selected biological traits included the morphological and behavioral characteristics of species. We used the distance sampling method to model the detection probability as an explicit function of environmental conditions and biological traits and implemented a model selection process to determine the relative importance of each group of covariates. Biological traits contributed to the variability of animal detectability more than environmental conditions, which had only a marginal effect. Detectability was best for large animals with uniform or disruptive markings that live in groups in the canopy top. Detectability was worst for small, solitary, terrestrial animals with mottled markings. In the terra firme rainforests which represent ~80% of the Amazonia and Guianas regions, our findings support the use of relative indices such as the encounter rate to compare population abundance between sites in species-specific studies. Even though terra firme rainforests may appear similar between regions of Amazonia and the Guianas, comparability must be ensured, especially in forests disturbed by human activity. The detection probability can be used as an indicator of species' vulnerability to hunting and, thus, to the risk of local extinction. Only a few biological trait covariates are required to correctly estimate the detectability of the majority of medium- and large-sized vertebrates. Thus, a biological trait model could be useful in predicting the detection probabilities of rare, uncommon or localized species for which few data are available to fit the detection function.
ISSN: 1051-0761

hal-01555267
https://hal.archives-ouvertes.fr/hal-01555267
DOI : 10.1002/eap.1549
PRODINRA : 396614
PUBMED : 28419598

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Cet article traite de la spécificité de l’activité touristique à Bali, fondée sur une identité locale forte et un riche patrimoine naturel et culturel mais aussi troublante en raison de l’importance et la complexité des jeux d’acteurs, ou encore des contextes sociaux, religieux et géopolitiques propres à ce territoire insulaire. Nous analyserons les liens pérennes ou non entre patrimoine et développement en focalisant sur ce qui fait l’image de marque de Bali sur les plans touristique et politique : le tourisme culturel. Cette étude de cas illustre les dynamiques d’acteurs dans le cadre de l’île de Bali où l’on constate une forte imbrication entre tourisme international, protection de l’environnement et promotion du patrimoine culturel. Vendue comme un paradis tropical, perçue comme l'île des Dieux, Bali se voit contrainte de mesurer les risques d'un tourisme culturel qui se transformerait trop rapidement en culture touristique. Des pistes seront proposées afin d’encourager l’ensemble des acteurs à œuvrer pour que le « dernier paradis » (last paradise) ne devienne pas un « paradis perdu » (lost paradise).
Since the 1930s, Bali has been generally seen as a traditional tourism destination quite fashionable. Nowadays, a new kind of tourism, rather esoteric if not totally spiritual, is emerging on this small “paradise” often referred as a natural untouched and cultural preserved island. To attire more international tourists, the “Island of Gods”, as the tourism promoters still name this tropical holiday paradise, is now also targeting on the industry of “well-being”. This article deals about the specificity of the local tourism activity which is based on a strong cultural identity and a rich natural and also religious heritage. Uncontrolled development of this predatory industry brings also a lot of new problems, such as pollution or acculturation. Here, our aim is to focus and analyse the real and false ties between heritage, development and tourism, always by keeping in mind that the regional motto about tourism policy still is to encourage “cultural tourism” as a real model (a “brand”, in fact) of success. We especially try to explain, in this current work (still in progress), the touristic situation in the main cultural site located on the island: Ubud. This small city, really boosting during the last decade, is worldwide reputed for the rich cultural performances and seen as “the” artistic capital of Bali. Ubud offers also a perfect example of an intense and dynamic bond between cultural heritage and economic development. Often for the best and sometimes also for the worse. In this rural but international spot, it seems that tourism business allows the local population to live in better ways and, sometimes, even to reborn, culturally speaking! Our case study shows also the big threats behind the current tourism policy: the large scale business occurred by globalization and all the tourism opportunities thus provided cannot hide the real weakness that for sure also concern the balinese way of thinking and living. Cultural tourism could rapidly be transformed in a dangerous kind of tourism of the culture, with all the big (and bad) changes the Balinese don’t want to see happening on their lovely and holy island. So, the present reflection conducts us to think more deeply on some new and alternative ways of developing tourism in Bali. Finally, our aim is to think, first by listening to the desire of the Balinese themselves, in which best manner this “last paradise” will not become a “lost paradise”.
Bali

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.5385
http://journals.openedition.org/etudescaribeennes/5385

Éditeur(s) : HAL CCSD IOP Publishing
Résumé : Radioactive pollutants are naturally present in microelectronic device materials and can be an issue for the reliability of devices. The main concern is alpha emitters that produce high-energy particles (a few MeV) that ionize the semiconductor and then trigger soft errors. The question is to know what kinds of radionuclides are present in the device, their location in the device and the abundance of each species. In this paper we describe tools that are required to address the issue of radioactive pollutants in electronic devices.
ISSN: 0268-1242

hal-01504448
https://hal.archives-ouvertes.fr/hal-01504448
DOI : 10.1088/1361-6641/aa5479

Éditeur(s) : HAL CCSD American Geophysical Union
Résumé : International audience
We recover the Holocene earthquake history of seven seismogenic normal faults in the Fucino system, central Italy. We collected 800 samples from the well-preserved limestone scarps of the faults and modeled their 36Cl concentrations to derive their seismic exhumation history. We found that > 30 large earthquakes broke the faults in synchrony over the last 12 ka. The seven faults released strain at the same periods of time, 12-9 ka, 5-3 ka, and 1.5-1 ka. On all faults, the strain accumulation and release occurred in 3-6 ka supercycles, each included a 3-5 ka phase of slow (≤ 0.5-2 mm/yr) strain accumulation in relative quiescence, followed by a cluster of three to four large earthquakes or earthquake sequences that released most of the strain in < 1-2 ka. The large earthquakes repeated every 0.5 ± 0.3 ka during the paroxysmal phases and every 4.3 ± 0.9 ka between those phases. Earthquakes on the northern faults produced twice larger surface slips (~ 2 m) and had larger magnitudes (Mw 6.2-6.7) than those on the southern faults. On most faults, the relative strain level was found to control the amount of slip and the time of occurrence of the next large earthquake. Faults entered a phase of clustered activity once they had reached a specific relative strain threshold. The Tre Monti fault is identified as the most prone to break over the next century. Our data document earthquake synchrony and clustering at a broader space and time scale than has been reported to date.
ISSN: 0148-0227

hal-00903460
https://hal.archives-ouvertes.fr/hal-00903460
DOI : 10.1002/jgrb.50299

Éditeur(s) : HAL CCSD
Résumé : International audience
The aim of the present study was to determine the effects of 40 km of cycling on the biomechanical and cardiorespiratory responses measured during the running segment of a classic triathlon, with particular emphasis on the time course of these responses. Seven male triathletes underwent four successive laboratory trials: (1) 40 km of cycling followed by a 10-km triathlon run (TR), (2) a 10-km control run (CR) at the same speed as TR, (3) an incremental treadmill test, and (4) an incremental cycle test. The following ventilatory data were collected every minute using an automated breath-by-breath system: pulmonary ventilation VE, l x min[-1]), oxygen uptake (VO2, ml x min(-1) x kg[-1]), carbon dioxide output (ml x min[-1]), respiratory equivalents for oxygen (VE/VO2) and carbon dioxide (VE/VCO2), respiratory exchange ratio (R) respiratory frequency (f, breaths x min[-1]), and tidal volume (ml). Heart rate (HR, beats x min[-1]) was monitored using a telemetric system. Biomechanical variables included stride length (SL) and stride frequency (SF) recorded on a video tape. The results showed that the following variables were significantly higher (analysis of variance, P < 0.05) for TR than for CR: VO2 [51.7 (3.4) vs 48.3 (3.9) ml x kg(-1) x min(-1), respectively], VE [100.4 (1.4) l x min(-1) vs 84.4 (7.0) l x min(-1)], VE/VO2 [24.2 (2.6) vs 21.5 (2.7)] VE/VCO2 [25.2 (2.6) vs 22.4 (2.6)], f[55.8 (11.6) vs 49.0 (12.4) breaths x min(-1)] and HR [175 (7) vs 168 (9) beats x min(-1)]. Moreover, the time needed to reach steady-state was shorter for HR and VO2 (1 min and 2 min, respectively) and longer for VE (7 min). In contrast, the biomechanical parameters, i.e. SL and SF, remained unchanged throughout TR versus CR. We conclude that the first minutes of the run segment after cycling in an experimental triathlon were specific in terms of VO2 and cardiorespiratory variables, and nonspecific in terms of biomechanical variables.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

hal-00720703
https://hal.univ-antilles.fr/hal-00720703
https://hal.univ-antilles.fr/hal-00720703/document
https://hal.univ-antilles.fr/hal-00720703/file/EJAP.pdf

Éditeur(s) : Université de Montpellier II
Résumé : Penaeid family shrimp constitute the first aquaculture product in the world in terms of commercial value. They are produced in third world countries of the sub-equatorial belt. Among the causes limiting their production, one is the presence of the WSSV (White Spot Syndrome Virus), a pathogenic agent that produces massive mortality. Our aim was to investigate the first stages of the viral infection, in order to be used as target of prophylactic actions. A fish cell line (SSN-1) was used as model to tentatively develop in vitro studies. Only defective particles were produced confirming the high specificity to crustacea of the infection with crustacean virus. Electron microscopy showed structural similarities between the WSSV and B, B2 and Baculo-B viruses of crabs. This suggests B2 may belong also to the family Nimaviridae, genus Whispovirus. This comparison with B2 virus gives the possibility to understand the role played by the tail-like extension of these viruses in the infectious process by attachment to the plasmic membrane at the beginning of the infection in its specific host.
Les crevettes de grande taille de la famille des Penaeidae constituent le premier produit aquacole en valeur commerciale à l'échelle planétaire. Elles sont produites à 99% dans les pays en voie de développement de la ceinture sub-équatoriale. Parmi les causes limitant leur production, le White Spot Syndrome Virus est l'agent pathogène ayant provoqué le plus des pertes dans le monde. Notre étude a été orientée vers la reconnaissance des premiers stades de l'infection, susceptibles d'être la cible d'une action prophylactique. Nous avons testé l'utilisation d'une lignée cellulaire de poisson SSN-1 afin d'étudier les possibilités d'un développement in vitro. Seules des particules défectives ont été produites confirmant la haute spécificité des infections à virus de crustacés. Les recherches en microscopie électronique ont montré une similarité structurale du WSSV avec les virus (B, B2 et Baculo-B) des crabes. Ceci suggère que ces agents (B2 et WSSV) seraient tout deux de la famille des Nimaviridae et du genre Whispovirus. La comparaison avec le virus B2 permet de comprendre le rôle clef joué par la partie caudale de ces virus dans l'infection par son attachement à la membrane plasmique lors de l'infection chez son hôte spécifique.

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/2008/these-6650.pdf
http://archimer.ifremer.fr/doc/00000/6650/

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
Hepatocellular carcinoma treatment by arterial infusion of cis-diamminedichloroplatinum-II (cisplatin) exhibits certain therapeutic efficacy. However, optimizations are required and the mechanisms underlying cisplatin proapoptotic effect remain unclear. The mitogen-activated protein kinase (MAPK) pathway plays a key role in cell response to cisplatin and the functional specificity of the isoform MAPK/ERK kinase 1 and 2 (MEK1/2) and ERK1/2 could influence this response. The individual contribution of each kinase on cisplatin-induced death was thus analyzed after a transient or stable specific inhibition by RNA interference in the human hepatocellular carcinoma cells Huh-7 or in knockout mice. We demonstrated here that ERK1 played a predominant role over ERK2 in cisplatin-induced death, whereas MEK1 and MEK2 acted in a redundant manner. Indeed, at clinically relevant concentrations of cisplatin, ERK1 silencing alone was sufficient to protect cells from cisplatin-induced death both in vitro, in Huh-7 cells and ERK1(-/-) hepatocytes, and in vivo, in ERK1-deficient mice. Moreover, we showed that ERK1 activity correlated with the induction level of the proapoptotic BH3-only protein Noxa, a critical mediator of cisplatin toxicity. On the contrary, ERK2 inhibition upregulated ERK1 activity, favored Noxa induction and sensitized hepatocarcinoma cells to cisplatin. Our results point to a crucial role of ERK1 in cisplatin-induced proapoptotic signal and lead us to propose that ERK2-specific targeting could improve the efficacy of cisplatin therapy by increasing ERK1 prodeath functions.
ISSN: 0143-3334

inserm-00814096
http://www.hal.inserm.fr/inserm-00814096
DOI : 10.1093/carcin/bgs317
PUBMED : 23042098

Éditeur(s) : HAL CCSD Réseau « Développement durable et territoires fragiles »
Résumé : The Green and Blue infrastructure (Trame verte et bleue –TVB) is a new conservation policy tool based on the notions of ecological network and corridor. The introduction of this new instrument through the French Grenelle environment commitments brings about some change in the spatial strategy of the conservation policy. Beyond the identification of priority conservation areas, ecological planning of all the territory is concerned. The TVB’s implementation process establishes the connection of multi and nested decisional and action levels. It thus creates specific situations of complexity and uncertainty that require innovation and perpetual change of governance. The study of the Auvergne region case through the adaptive governance analytical framework highlights the potential fruitful role of Regional nature parks in such dynamics of change and learning. Mots-clés : aménagement durable des territoires, biodiversité, réseau écologique, corridor écologique, gouvernance adaptative, socio-écosystème, trame verte et bleue Keywords : Sustainable landplaning, Biodiversity, Ecological network, Adaptive governance, socio-ecosystem
La Trame verte et bleue (TVB), nouveau dispositif d’action publique visant à enrayer la perte de biodiversité traduit un renouvellement des référentiels de justification des politiques de conservation et de leur stratégie territoriale. Il s’agit d’intégrer la planification écologique dans l’aménagement de l’ensemble du territoire. Le processus de territorialisation de la TVB met en rapport de multiples niveaux de décision et d’action imbriqués. Il crée de ce fait des configurations inédites de complexité et d’incertitude et implique des innovations en termes de gouvernance que le cadre analytique de la gouvernance adaptative permet d’appréhender. En nous appuyant sur l’exemple du Parc Naturel Régional des Volcans d’Auvergne, nous analysons le rôle que ces institutions sont susceptibles de jouer dans ces dynamiques de changement et d’apprentissage socio-technique et politique qui conditionnent une mise en œuvre effective de la TVB.
ISSN: 1772-9971

hal-01195370
https://hal.archives-ouvertes.fr/hal-01195370
DOI : 10.4000/developpementdurable.9675
PRODINRA : 269288