Éditeur(s) : Taylor and Francis
Résumé : A new cumacean genus and species, Thalycrocuma sarradini gen. et sp. nov., belonging to the family Nannastacidae is described from several sites of the Lucky Strike hydrothermal vent field (Mid-Atlantic Ridge, 37N, 1700 m depth). The new genus differs from others in the family by males lacking exopods on the pereopods 3 and 4 and having an antenna with a five-articulate peduncle and a short flagellum. This is the first cumacean species that could be considered, at the moment, as endemic from hydrothermal vent areas. Data on the accompanying fauna including other cumacean species (Cyclaspis longicaudata, Bathycuma brevirostre, Procampylaspis sp. and Makrokylindrus sp.) and some ecological remarks are included. A key for the currently known genera of the family Nannastacidae is provided and the taxonomic position of some genera is discussed.
Marine Biology Research (1745-1000) (Taylor and Francis), 2008-06 , Vol. 4 , N. 3 , P. 180-192

Droits : 2008 Taylor & Francis Group
http://archimer.ifremer.fr/doc/2008/publication-4358.pdf
DOI:10.1080/17451000801898576
http://archimer.ifremer.fr/doc/00000/4358/

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
New U–Pb monazite, zircon, and xenotime ages date the Late Carboniferous crystallization of the anatectic Vialais granite in the Montagne Noire Axial Zone and the high-temperature deformation and metamorphism of the augen gneiss (Ordovician granite protolith) from which the granite was likely derived. The U–Pb monazite ages obtained from the augen gneiss (308 ± 3 Ma), late kinematic Vialais granite (303 ± 4 Ma), and post-kinematic leucogranite (298 ± 2 Ma), bracket the high-temperature deformation and metamorphism at ~ 310–300 Ma, clearly postdating regional contraction and nappe emplacement (> 320 Ma). The planar–linear and locally linear fabrics in the augen gneiss outline a regional-scale double dome structure (Caroux and Espinouse sub-domes) containing smaller (km-scale) upright folds. Compared to the Caroux sub-dome, the larger, migmatitic Espinouse sub-dome contains abundant leucosome, leucogranite bodies and late-kinematic intrusions (Vialais granite). The Vialais granite displays a weak magmatic foliation that defines the main layering of the Espinouse migmatite. Ellipsoidal quartz–sillimanite nodules concentrated above the roof of the granite recorded an increment of strain (vertical shortening, E–NE elongation) during granite emplacement and crystallization, consistent with the extension event that exhumed the domes. These new geochronological and structural data suggest that the Montagne Noire double dome formed in a pull-apart structure within a dextral strike–slip system. Upright folding in the sub-domes has been traditionally assigned to a regional contraction event; alternatively, we propose that local contraction is associated with the convergence of low-viscosity crust beneath the upper crust pull-apart. Dynamic models of extension of hot crust indicate that contraction at depth is generated by flow of low-viscosity orogenic crust converging and rising to fill the gap created by upper crust extension. This interpretation solves the long-standing problem of apparent coeval contraction and extension in the Montagne Noire double dome and establishes migmatite dome emplacement in strike–slip corridors as a style of late Variscan tectonics.
ISSN: 0040-1951

insu-01112009
https://hal-insu.archives-ouvertes.fr/insu-01112009
DOI : 10.1016/j.tecto.2014.12.002

Éditeur(s) : HAL CCSD
Résumé : International audience
In many geological reservoirs, open fractures or fault zones generally induce high spatial variability of hydrodynamical properties and shape the main deep-seated flow paths. It is of crucial interest to determine their structure and properties in order to achieve a sound and sustained exploitation of resources or to estimate the risk of failure of any underground storage. Tiltmeters have emerged as new tools to observe deformation generated by groundwater flow. As such instruments are highly sensitive to pressure gradients, they are perfectly suited for monitoring channelized flow in connected fractures and fault zones. Hence, they provide a unique insight of these reservoirs' geometry and dynamics over broad time scales. Here we demonstrate that continuous tilt data from surface long baseline tiltmeters (LBT) can be used alone to evaluate the general functioning of a fractured hardrock system and estimate the hydraulic properties of its main conductive features. The study is applied to the pumping site of Ploemeur observatory (Brittany, France) which is well documented and instrumented, and therefore forms a convenient setting for introducing LBT as tools for fractured media hydrology. On the short term, tilt signals are strongly correlated with pumping cycles and associated head level changes in well-connected boreholes. Besides, when pumps are stopped the maximal tilt direction is systematically perpendicular to a subvertical fault zone whose azimuth of strike has thereby been refined down to degree precision. By using a semi-analytical model of deformation, we establish the link between tilt and pressure change during pumping interruptions which then allows for hydraulic properties estimation from tilt measurements only. Finally, we validate our results with previous estimates obtained from other studies and discuss the orientation of future work that could enhance these estimates.
AGU Fall Meeting 2014
San Francisco, United States

insu-01093437
https://hal-insu.archives-ouvertes.fr/insu-01093437

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Mongolia represents the northernmost area affected by the India–Asia collision, and it is actively deformed along transpressive belts closely associated with large-scale strike-slip faults. The active and past mantle flow beneath this region is, however, poorly known. In order to investigate deep mantle deformation beneath central Mongolia and its relation with the surrounding major structures such as the Siberian craton, the Gobi–Altay belt and the Baikal rift, a NS-trending profile of broadband seismic stations has been deployed in the summer 2003 from the southern Siberian craton to the Gobi–Altay range, crossing the entire Hangay dome. Mantle flow is deduced from the splitting of teleseismic shear waves such as SKS phases. In eastern Mongolia, the permanent station ULN in Ulaanbaatar reveals the presence of two anisotropic layers, the upper one being oriented NE–SW, close to the trend of lithospheric structures and the lower one NW–SE, close to the trend of Eurasia absolute plate motion. Along the NS profile in central Mongolia, seismic anisotropy deduced from SKS splitting reveals a homogeneous NW–SE trending structure, fully consistent with the observations made in the Altay–Sayan in western Mongolia. The observed delay times of 1.5 to more than 2.0 s favor consistent mantle flow over large mantle thicknesses. Since the lithosphere is less than 100 km thick beneath central Mongolia and since the observed fast directions are parallel to the trend of the lithospheric structures but also close to the trend of the absolute plate motion, we propose that both the lithosphere and the asthenosphere may join their anisotropic effects beneath central Mongolia to explain the large delay times. Although GPS vectors represent the instantaneous displacement of the Earth's surface and SKS splitting the time and vertical integration of finite strain at depth, we use the opportunity of the dense geodetic measurements available in this region to discuss the anisotropy pattern in term of present-day deformation. In the Eurasia-fixed reference frame, GPS and SKS both depict a similar trend beneath central Mongolia, suggesting a lithospheric block “escaping” toward the east that could orient olivine a-axes in the upper mantle, within a transpressive tectonic regime. A different behaviour is observed in western Mongolia: the GPS vectors trend NS, close to the regional compression direction, whereas the fast SKS directions trend EW, suggesting a tectonic regime close to a mode of axial shortening, generating the development of an EW-trending foliation at depth. We therefore propose that Mongolia is a place where active and frozen lithospheric deformation may add their effects, together with the sublithospheric flow. In the three sources of anisotropy inferred, a fundamental role is played by the Siberian craton that acted as an undeformable core of the continent through time: the frozen Paleozoic and Mesozoic structures wrap around the craton, building up the fast anisotropic direction pattern; the present-day sublithospheric flow induced by the plate motion is likely deflecting around its deep roots; finally, the present-day tectonic regime appears to be controlled by the presence of the craton to the north.
ISSN: 0012-821X

hal-00407853
https://hal.archives-ouvertes.fr/hal-00407853
https://hal.archives-ouvertes.fr/hal-00407853/document
https://hal.archives-ouvertes.fr/hal-00407853/file/Barruol_SKS_Mongolia_EPSL2008_hal.pdf
DOI : 10.1016/j.epsl.2008.07.027

Éditeur(s) : NRC
Résumé : In self-feeding conditions, a few individual sea bass (Dicentrarchus labrax (L., 1758)) display strong activity in striking the food dispenser, whereas the remaining individuals of the group actuate the feeder weakly or never. Here, we investigated the effects of removal of the individuals showing dominant activity on the social and feeding behaviours in groups of juvenile sea bass. Following removal, new fish showing a dominant self-feeding activity quickly appear. They always come from the group of fish that have a low number of triggering actuations. This observation shows that it takes less time, about 5 days after the removal of dominant triggerers vs. 14 days at the beginning, for the re-establishment of the behavioural structure, suggesting the possibility of social transmission between individuals. The fish that show weak triggering activity seem to reach the high-food triggering level without obvious signs of competition. This experiment reveals the importance of the food-demand behavioural structure: the fish displaying the highest activity lead to a general food distribution and play a dominant role in feeding the entire group. Functional plasticity in this role within individuals is also demonstrated, indicating that the high-triggering function is essential for the group and not for the individual themselves.
Au sein d'un groupe de bars (Dicentrarchus labrax (L., 1758)) placés en auto-nourrissage, quelques individus disposent d'une activité forte de déclenchement volontaire du distributeur d'aliments. Les autres poissons du groupe disposent d'une activité de demande faible voire nulle. Ici, nous avons étudié l'impact du retrait des poissons à forte activité sur le comportement alimentaire et social de groupes de bars juvéniles. De nouveaux individus à forte activité réapparaissent rapidement, provenant exclusivement de la classe de poissons de faible demande. Cinq jours en moyenne suffisent après le retrait, contre 14 jours au début de l'expérience, pour que la structure comportementale se rétablisse suggérant l'existence d'une transmission sociale entre les individus. Ces poissons de faible activité semblent de plus atteindre leur nouvelle fonction sans aucun signe de compétition. Cette expérience révèle d'abord l'importance de la structure de la demande alimentaire puisqu'elle réapparaît après le retrait. Elle montre également que l'activité des forts manipulateurs conduit à une distribution générale de l'aliment et contribue à nourrir le groupe en entier. L'étude montre enfin une plasticité fonctionnelle indiquant que seule la fonction de manipulateur fort est essentiel pour la stabilité du groupe, non l'identité des individus par elle-même.
Canadian journal of zoology (0008-4301) (NRC), 2008-09 , Vol. 86 , N. 9 , P. 1015-1023

Droits : 2008 NRC Canada
http://archimer.ifremer.fr/doc/2008/publication-4766.pdf
DOI:10.1139/Z08-077
http://archimer.ifremer.fr/doc/00000/4766/

Éditeur(s) : Soc Geol France
Résumé : The Lesser Antilles subduction zone has produced no recent strong thrust earthquakes, making it difficult to quantify the seismic hazard from such events. The Lesser Antilles arc has a low subduction rate and an accretionary wedge that is very wide at its southern end. To investigate the effect of the wedge on seismogenesis, numerical models of forearc thermal structure were constructed along six transects perpendicular to the arc in order to determine the thermally predicted width of the seismogenic zone. The geometry of each section is constrained by published seismic profiles and crustal models derived from gravity and seismic data and by earthquake hypocenters at depth. A major constraint on the deep part of the model is that mantle temperature beneath the volcanic arc should achieve a temperature of 1,100 degrees C to generate partial melts. Predicted surface heat flow is compared to the available heat flow observations. Thermal modeling results indicate a systematic southward increase in the width of the seismogenic zone, more than doubling in width from north to south and corresponding to a dramatic southward increase in forearc width (distance from the arc to the deformation front of the accretionary wedge). The minimum width of the seismogenic zone (distance between the intersections of the subduction interface with the 150 degrees C and 350 degrees C isotherms) increases from about 80 km, north of 16 degrees N, to 230 km, at 13 degrees N. The maximum width (between the 100 degrees C and 450 degrees C isotherms) ranges from about 150 km in the north to up to 320 km in the south. This large variation in the width of the seismogenic zone is a consequence of the increasing width of the accretionary wedge to the south, caused by the increased thickness of sediment on the subducting plate. There is good agreement between the thermally predicted seismogenic limits and the sparse distribution of recorded thrust earthquakes, which are observed only in the northern portion of the arc. Possible scenarios for mega-thrust earthquakes are discussed. Depending on the segment length (along-strike) of the rupture plane, the occurrence of an event of magnitude 8-9 cannot be excluded.
L’absence de grands séismes récents à mécanismes chevauchants dans la zone de subduction des Petites Antilles rend difficile l’évaluation de l’aléa sismique lié à de tels événements. L’arc des Petites Antilles est caractérisé par une faible vitesse de subduction et par la présence d’un prisme d’accrétion très développé à son extrémité méridionale. Afin d’évaluer les effets de la largeur de ce prisme sur la genèse des séismes, nous avons étudié six sections perpendiculaires à l’arc, du nord au sud de celui-ci, pour déterminer la largeur de la zone sismogène prédite par les modèles thermiques appliqués à chacune de ces coupes. La géométrie de ces dernières est contrainte par les profils sismiques publiés, par les modèles de structure crustale déduits des données gravitaires et sismiques, et enfin par la distribution des hypocentres des séismes. Un contrôle important permettant de tester la validité des modèles thermiques en profondeur est qu’une température minimale de 1 100oC, compatible avec la fusion partielle du manteau hydraté, doit être atteinte sous l’arc volcanique actif. Par ailleurs, le flux thermique en surface prédit par ces modèles doit être compatible avec les mesures de flux de chaleur. Les modèles thermiques retenus d’après ces critères montrent une augmentation du simple au double vers le sud de la largeur de la zone sismogène, qui correspond à un élargissement considérable de la taille du domaine avant-arc. En effet, la largeur minimale de la zone sismogène (définie comme la distance entre les intersections de l’interface des plaques avec les isothermes 150o et 350oC) augmente d’environ 80 km au nord de 16oN jusqu’à 230 km à 13oN. La largeur maximale de cette zone (définie par les intersections de l’interface avec les isothermes 100o et 450oC) augmente, quant à elle, d’environ 150 km au nord jusqu’à 320 km au sud de l’arc. Cette variation considérable est la conséquence de l’augmentation de la largeur du prisme d’accrétion, elle-même causée par l’accumulation croissante des sédiments déposés sur la plaque plongeante. Les largeurs de la zone sismogène prédites à l’aide des modèles thermiques sont en bon accord avec les rares données disponibles sur les séismes à mécanismes chevauchants dans la partie nord de l’arc. Les scénarios possibles relatifs à des méga-séismes de ce type n’excluent pas de futurs événements atteignant des magnitudes de 8 à 9.
Bulletin De La Societe Geologique De France (0037-9409) (Soc Geol France), 2013 , Vol. 184 , N. 1-2 , P. 47-59

Droits : 2013 Societe Geologique de France
http://archimer.ifremer.fr/doc/00140/25140/29432.pdf
DOI:10.2113/gssgfbull.184.1-2.47
http://archimer.ifremer.fr/doc/00140/25140/

Éditeur(s) : HAL CCSD American Geophysical Union (AGU)
Résumé : International audience
Detailed seafloor mapping in the area east of Taiwan revealed trench-parallel stretching and folding of the Ryukyu forearc and lateral motion of the accretionary wedge under oblique convergence. East of 122ø40'E, a steep accretionary wedge is elongated in an E-W direction. A major transcurrent right-lateral strike-slip fault accommodates the strain partitioning caused by an oblique convergence of 40 ø. A spectacular out-of-sequence thrust may be related to the subduction of a structural high lying in the axis of the N-S trending Gagua Ridge. This asperity is likely responsible for the uplift of the accretionary wedge and forearc basement and may have augmented strain partitioning by increasing the coupling between the two plates. West of 122ø40'E, the low-taper accretionary wedge is sheared in a direction subparallel to the convergence vector with respect to the Ryukyu Arc. The bayonet shape of the southern Ryukyu Arc slope partly results from the recent (re)opening of the southern Okinawa Trough at a rate of about 2 to 4 cm/yr. Right-lateral shearing of the sedimentary forearc with respect to the nonlinear Ryukyu backstop generates trench-parallel extension in the forearc sediment sequence at dilational jogs and trench-parallel folding at compressive jogs. The Hoping Basin lies above a diffuse trench/trench/fault (TTF) or TFF unstable triple junction moving toward the south along a N-S transform zone which accommodates the southward drift of the Ryukyu Arc with respect to Eurasia.
ISSN: 0278-7407

hal-01261555
https://hal.archives-ouvertes.fr/hal-01261555
https://hal.archives-ouvertes.fr/hal-01261555/document
https://hal.archives-ouvertes.fr/hal-01261555/file/Lallemand_et_al-1999-Tectonics.pdf
DOI : 10.1029/1998TC900011

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
This paper aims to present an overview on the influence of rheological heterogeneity and mechanical anisotropy on the deformation of continents. After briefly recapping the concept of rheological stratification of the lithosphere, we discuss two specific issues: (1) as supported by a growing body of geophysical and geological observations, crust=mantle mechanical coupling is usually efficient, especially beneath major transcurrent faults which probably crosscut the lithosphere and root within the sublithospheric mantle; and (2) in most geodynamic environments, mechanical properties of the mantle govern the tectonic behaviour of the lithosphere. Lateral rheological heterogeneity of the continental lithosphere may result from various sources, with variations in geothermal gradient being the principal one. The oldest domains of continents, the cratonic nuclei, are characterized by a relatively cold, thick, and consequently stiff lithosphere. On the other hand, rifting may also modify the thermal structure of the lithosphere. Depending on the relative stretching of the crust and upper mantle, a stiff or a weak heterogeneity may develop. Observations from rift domains suggest that rifting usually results in a larger thinning of the lithospheric mantle than of the crust, and therefore tends to generate a weak heterogeneity. Numerical models show that during continental collision, the presence of both stiff and weak rheological heterogeneities significantly influences the large-scale deformation of the continental lithosphere. They especially favour the development of lithospheric-scale strike-slip faults, which allow strain to be transferred between the heterogeneities. An heterogeneous strain partition occurs: cratons largely escape deformation, and strain tends to localize within or at the boundary of the rift basins provided compressional deformation starts before the thermal heterogeneity induced by rifting are compensated. Seismic and electrical conductivity anisotropies consistently point towards the existence of a coherent fabric in the lithospheric mantle beneath continental domains. Analysis of naturally deformed peridotites, experimental deformations and numerical simulations suggest that this fabric is developed during orogenic events and subsequently frozen in the lithospheric mantle. Because the mechanical properties of single-crystal olivine are anisotropic, i.e. dependent on the orientation of the applied forces relative to the dominant slip systems, a pervasive fabric frozen in the mantle may induce a significant mechanical anisotropy of the whole lithospheric mantle. It is suggested that this mechanical anisotropy is the source of the so-called tectonic inheritance, i.e. the systematic reactivation of ancient tectonic directions; it may especially explain preferential rift propagation and continental break-up along pre-existing orogenic belts. Thus, the deformation of continents during orogenic events results from a trade-off between tectonic forces applied at plate boundaries, plate geometry, and the intrinsic properties (rheological heterogeneity and mechanical anisotropy) of the continental plates.
ISSN: 0040-1951

hal-01389719
http://hal.univ-reunion.fr/hal-01389719
http://hal.univ-reunion.fr/hal-01389719/document
http://hal.univ-reunion.fr/hal-01389719/file/vauchez_etal_rheology_1998_hal.pdf
DOI : 10.1016/S0040-1951(98)00137-1

Éditeur(s) : HAL CCSD Springer Verlag (Germany) Springer Verlag
Résumé : International audience
We report here U-series and trace element data for an olivine-melilitite lava flow, erupted in 1957 in the Virunga volcanic field and known as the Mugogo eruption. Petrological and geochemical data show that the Mugogo magma represents a primary mantle melt, derived from a low degree of melting of a metasomatised mantle source. It is highly enriched in very incompatible trace elements (e.g. more than 300-fold compared to primitive mantle for Th), with a distinctly lower enrichment in Rb, Ba and Sr. The high Th/U and low (230Th/232Th) ratios (4.4 and 0.750, respectively, with a (230Th/238U) ratio of 1.09) are close to the values found for the Nyamuragira basanites. But the most striking feature is the very low (226Ra/230Th) ratio of 0.48, the lowest ever measured in a mafic volcanic rock. The most probable origin of this Ra deficit is the presence of phlogopite (having a high Ra partition coefficient) in the lithospheric mantle, either as a residual phase during low-degree isobaric melting (in batch-melting or a diffusion-controlled melting models), or in a phlogopite-bearing upper mantle through which the melt migrates and equilibrates (in an equilibrium porous flow model commonly used to describe adiabatic melting). The disequilibrium pattern (230Th) > (238U) > (210Pb) ≫ (226Ra), reversed compared to the pattern observed in the Oldoinyo Lengai natrocarbonatite, suggests that a carbonatite melt might have been involved to explain the Ra deficit. We thus discuss the possibility of an early separation of a Ra-enriched carbonate melt either from the olivine-melilitite melt or from a carbonated mantle source, followed by the production of a low-degree melt of olivine-melilitite composition, but the lack of available experimental, petrological and geochemical evidences makes this process somewhat speculative at present. Further studies of recent (<5 ky) olivine-melilitites are needed to check whether the large Ra deficit is a general characteristic of this type of magma that can be used to constrain models of its formation.
ISSN: 0010-7999

hal-01174173
https://hal.archives-ouvertes.fr/hal-01174173
DOI : 10.1007/s00410-015-1124-9

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
The susceptibility of Anopheles mosquitoes to Plasmodium infections relies on complex interactions between the insect vector and the malaria parasite. A number of studies have shown that the mosquito innate immune responses play an important role in controlling the malaria infection and that the strength of parasite clearance is under genetic control, but little is known about the influence of environmental factors on the transmission success. We present here evidence that the composition of the vector gut microbiota is one of the major components that determine the outcome of mosquito infections. A. gambiae mosquitoes collected in natural breeding sites from Cameroon were experimentally challenged with a wild P. falciparum isolate, and their gut bacterial content was submitted for pyrosequencing analysis. The meta-taxogenomic approach revealed a broader richness of the midgut bacterial flora than previously described. Unexpectedly, the majority of bacterial species were found in only a small proportion of mosquitoes, and only 20 genera were shared by 80% of individuals. We show that observed differences in gut bacterial flora of adult mosquitoes is a result of breeding in distinct sites, suggesting that the native aquatic source where larvae were grown determines the composition of the midgut microbiota. Importantly, the abundance of Enterobacteriaceae in the mosquito midgut correlates significantly with the Plasmodium infection status. This striking relationship highlights the role of natural gut environment in parasite transmission. Deciphering microbe-pathogen interactions offers new perspectives to control disease transmission.
ISSN: 1553-7366

hal-01546176
https://hal.archives-ouvertes.fr/hal-01546176
DOI : 10.1371/journal.ppat.1002742

Éditeur(s) : HAL CCSD Society for Molecular Biology and Evolution
Résumé : International audience
Complex nongradual evolutionary processes such as gene remodeling are difficult to model, to visualize, and to investigate systematically. Despite these challenges, the creation of composite (or mosaic) genes by combination of genetic segments from unrelated gene families was established as an important adaptive phenomena in eukaryotic genomes. In contrast, almost no general studies have been conducted to quantify composite genes in viruses. Although viral genome mosaicism has been well-described, the extent of gene mosaicism and its rules of emergence remain largely unexplored. Applying methods from graph theory to inclusive similarity networks, and using data from more than 3,000 complete viral genomes, we provide the first demonstration that composite genes in viruses are 1) functionally biased, 2) involved in key aspects of the arm race between cells and viruses, and 3) can be classified into two distinct types of composite genes in all viral classes. Beyond the quantification of the widespread recombination of genes among different viruses of the same class, we also report a striking sharing of genetic information between viruses of different classes and with different nucleic acid types. This latter discovery provides novel evidence for the existence of a large and complex mobilome network, which appears partly bound by the sharing of genetic information and by the formation of composite genes between mobile entities with different genetic material. Considering that there are around 10E31 viruses on the planet, gene remodeling appears as a hugely significant way of generating and moving novel sequences between different kinds of organisms on Earth.
ISSN: 1759-6653

Droits : http://creativecommons.org/licenses/by/
hal-01324848
http://hal.upmc.fr/hal-01324848
http://hal.upmc.fr/hal-01324848/document
http://hal.upmc.fr/hal-01324848/file/Genome%20Biol%20Evol-2014-Jachiet-2195-205.pdf
DOI : 10.1093/gbe/evu168

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Active faults from the Campo de Dalías (SE Betic Cordillera) allow us to constrain the deformation styles involved in the development of segmented oblique-slip faults. This sector constitutes the widest outcrop of Plio-Quaternary sediments in the northern boundary of the Alboran Sea. It has emerged since the Late Pliocene, and therefore provides recent deformation markers that are not disturbed by erosive processes. The faults started to grow during the Pleistocene, reactivating previous hybrid joints, with a normal-dextral slip. We present a detailed map of the largest fault in the area, the Loma del Viento fault, comprising six onshore segments. Based on field work and aerial photography, the distributions of the contiguous joints have been mapped, and the joints reactivated as faults are identified. Some of these fault segments are hard-linked, and fault slip enhances toward the linkage sectors between them with associated sedimentary depocenters. An electrical tomography profile reveals the wedge geometry of a unit of Pleistocene conglomerates and red silts that were coevally deposited during the fault movement. Long-term slip rate in the central part of the fault is estimated at 0.07 ± 0.03 mm/y. In addition, a seismic crisis nucleated close to the Loma del Viento fault during November 2010 was recorded. Moment tensor analysis of the two mainshocks (Mw 3.5 and 4.2) provides a focal solution indicating a N120°E striking right-lateral strike-slip fault. The corrugated morphology of the Loma del Viento fault may have influenced its seismic behavior. Some of the fault segments are oblique to the general motion of the fault. These oblique segments would provide higher resistance against the general fault motion and could lock the fault, leading to accumulate elastic energy.
ISSN: 0040-1951

hal-00750357
https://hal.archives-ouvertes.fr/hal-00750357
DOI : 10.1016/j.tecto.2011.12.001

Éditeur(s) : HAL CCSD American Chemical Society
Résumé : International audience
Constitutive activation of the PI3K/mTOR signaling pathway contributes to carcinogenesis and metastasis in most, if not all, breast cancers. From a chromene backbone reported to inhibit class I PI3K catalytic subunits, several rounds of chemical syntheses led to the generation of a new collection of chromologues that showed enhanced ability to kill PI3K-addicted cancer cells and to inhibit Akt phosphorylation at serine 473, a hallmark of PI3K/mTOR activation. This initial screen uncovered a chromene designated DHM25 that exerted potent antitumor activity against breast tumor cell lines. Strikingly, DHM25 was shown to be a selective and covalent inhibitor of mTOR using biochemical and cellular analyses, modeling, and a large panel of kinase activity assays spanning the human kinome (243 kinases). Finally, in vivo, this novel drug was an efficient inhibitor of growth and metastasis of triple-negative breast cancer cells, paving the way for its clinical application in oncology
ISSN: 0022-2623

hal-01187307
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01187307
DOI : 10.1021/acs.jmedchem.5b00991
PUBMED : 26237138

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
Background: Myosin II (or Myosin Heavy Chain II, MHCII) is a family of molecular motors involved in the contractile activity of animal muscle cells but also in various other cellular processes in non-muscle cells. Previous phylogenetic analyses of bilaterian MHCII genes identified two main clades associated respectively with smooth/non-muscle cells (MHCIIa) and striated muscle cells (MHCIIb). Muscle cells are generally thought to have originated only once in ancient animal history, and decisive insights about their early evolution are expected to come from expression studies of Myosin II genes in the two non-bilaterian phyla that possess muscles, the Cnidaria and Ctenophora. Results: We have uncovered three MHCII paralogues in the ctenophore species Pleurobrachia pileus. Phylogenetic analyses indicate that the MHCIIa /MHCIIb duplication is more ancient than the divergence between extant metazoan lineages. The ctenophore MHCIIa gene (PpiMHCIIa) has an expression pattern akin to that of ``stem cell markers'' (Piwi, Vasa...) and is expressed in proliferating cells. We identified two MHCIIb genes that originated from a ctenophore-specific duplication. PpiMHCIIb1 represents the exclusively muscular form of myosin II in ctenophore, while PpiMHCIIb2 is expressed in non-muscle cells of various types. In parallel, our phalloidin staining and TEM observations highlight the structural complexity of ctenophore musculature and emphasize the experimental interest of the ctenophore tentacle root, in which myogenesis is spatially ordered and strikingly similar to striated muscle formation in vertebrates. Conclusion: MHCIIa expression in putative stem cells/proliferating cells probably represents an ancestral trait, while specific involvement of some MHCIIa genes in smooth muscle fibres is a uniquely derived feature of the vertebrates. That one ctenophore MHCIIb paralogue (PpiMHCIIb2) has retained MHCIIa-like expression features furthermore suggests that muscular expression of the other paralogue, PpiMHCIIb1, was the result of neofunctionalisation within the ctenophore lineage, making independent origin of ctenophore muscle cells a likely option.
ISSN: 1471-2148

hal-01544486
https://hal.archives-ouvertes.fr/hal-01544486
DOI : 10.1186/1471-2148-12-107

Éditeur(s) : HAL CCSD American Geophysical Union
Résumé : International audience
We investigate upper mantle anisotropy beneath the Pyrenean range along three N-S profiles across the mountain belt. The results of a first profile that operated in 1993 in the central part of the belt have been presented elsewhere. We present the results of two other profiles that ran in 1995-1996 and 1996-1997 in the eastern and western part of the belt, respectively and propose an interpretation of the whole results. Teleseismic shear waves (SKS, SKKS, and PKS) are used to determine splitting parameters: the fast polarization direction φ and the delay time δt. Teleseismic shear wave splitting in the eastern Pyrenees displays homogeneous φ values trending N100°E and δt values in the range 1.1 to 1.5 s. A station located in the southern Massif Central, 100 km north of the range, is characterized by different splitting parameters (φ = N70°E, δt = 0.7 s). In the western part of the belt, anisotropy parameters are similar across the whole belt (φ = N110°E and δt = 1.3 to 1.5 s). Most of the measured delay times, including those obtained in the central part of the range, are above the global average of the SKS splitting (around 1 s). At the belt scale, φ is generally poorly correlated with recent estimations of the absolute plate motion, which predicts a fast direction ranging between N50°E and N80°E. Instead, the orientation of φ (N100°E) is parallel to the trend of the Pyrenean belt but also to Hercynian preexisting structures. This parallelism supports an anisotropy primarily related to frozen or active lithospheric structures. We show that a signature related to the Pyrenean orogeny is likely for the stations located in the internal domains of the belt. By contrast, the anisotropy measured at the stations located on the external parts of the belt could reflect a pre-Pyrenean (Hercynian) deformation. We suggest that a late Hercynian strike-slip deformation is responsible for this frozen upper mantle anisotropy and that the Pyrenean tectonic fabric developped parallel to this preexisting fabric. Finally, no particularly strong splitting is related to the North Pyrenean Fault, commonly believed to represent the plate boundary between Iberia and Eurasia.
ISSN: 2169-9313

hal-01388841
http://hal.univ-reunion.fr/hal-01388841
http://hal.univ-reunion.fr/hal-01388841/document
http://hal.univ-reunion.fr/hal-01388841/file/Barruol_Aniso_Pyr_JGR1998.pdf
DOI : 10.1029/98JB02790

Éditeur(s) : HAL CCSD
Résumé : The territory of Armenia was located in the collision zone between Arabia and Eurasia, and is the seat of active intercontinental deformations, which was attested by the many historical earthquakes that have occurred in this region. All these destructive earthquakes show a strong regional seismic activity, and therefore it is important to evaluate the seismic hazard associated with active structures that generates this seismicity.This study presents the results of the analysis of the active tectonics within the northwestern and southeastern extensions of the Pambak-Sevan-Syunik fault (PSSF), a major right-lateral strike-slip fault cutting through Armenia (NW - SE). Quantifying the deformations in terms of geometry, kinematics, slip rates and earthquake activity, using cosmogenic 3He, OSL/IRSL and radiocarbon dating techniques, reveal different behaviors between the two regions.Within the northwestern extension, in the region of Amassia, the PSSF bends to the west and splits into two main WNW-ESE trending reverse faults defining a compressional pop-up structure. We estimate an uplift rate and a shortening rate of 0.5 ± 0.1 mm/y and 1.4 ± 0.6 mm/y, respectively. This suggests that most of the ~2 mm/y right lateral movement of the PSSF seems to be absorbed within the Amasia pop-structure.Within the southeastern extension, in the region of Tsghuk volcano, the PSSF shows signs of dying out at the southernmost tip of the Syunik graben. A very slow NS trending normal faulting associated with a slight right-lateral movement characterizes the tectonic activity in the region of Tsghuk volcano. We estimate vertical slip rates, EW stretching rate, and right-lateral slip rate of ~0.2 mm/y, ~0.1 mm/y and ~0.05 mm/y, respectively. These results lead to the conclusion that the right lateral movement observed further north along the PSSF is mainly transferred within other active faults further west within the Karabagh (Hagari fault or other structures further northwestwards).
L’Arménie se situe dans la zone de collision entre Arabie et Eurasie et est le siège d’une déformation intracontinental active comme l’atteste les nombreux tremblements de terre historiques qui s’y sont produits. Tous ces séismes, destructeurs, attestent d’une forte activité sismique régionale, et il est par conséquent important d'évaluer l’aléa sismique associé aux structures actives qui génère cette sismicité.Le travail présenté ici, expose les résultats de l’analyse de la tectonique active au niveau des terminaisons nord-ouest et sud-est de la faille de Pambak-Sevan-Syunik (PSSF), une des failles décrochant majeure qui traverse l'Arménie du NW au SE. La quantification des déformations en termes de géométrie, cinématique, vitesse de glissement et paléosismicité, en utilisant les méthodes de datation 3He cosmogénique, OSL/IRSL et radiocarbone, révèlent des comportements différents entre les deux régions.Au niveau de la terminaison nord-ouest, dans la région d’Amassia, la faille PSSF s’incurve vers l'ouest et se subdivise en deux branches de direction WNW-ESE, et de cinématique inverse, définissant une structure en pop-up. Nous estimons une vitesse de soulèvement de 0.5 ± 0.1 mm/an et une vitesse de raccourcissement NNE-SSW de 1.4 ± 0.6 mm/an. Ces résultats suggère que l’essentiel des ~2 mm/an de mouvement dextre estimés le long de la faille de PSSF sont absorbés au niveau du pop-up d’Amassia.Au niveau de la terminaison sud-est, dans la région du volcan Tsghuk, la faille PSSF semble disparaitre. Le peu d’activité tectonique est caractérisée par des failles normales sub-méridiennes associées à une légère composante décrochant dextre. Nous déterminons une vitesse de glissement vertical de ~0,2 mm/an, une vitesse d’extension ~EW de ~0,1 mm/an associée à une composante dextre de ~0,05 mm/an. Ces résultats suggèrent que le mouvement dextre observé le long de la faille de PSSF plus au nord, a été transféré sur d'autres failles plus à l'ouest dans le Karabakh (faille Hagari ou autres structures situés encore plus au NW).
https://tel.archives-ouvertes.fr/tel-01621440

NNT : 2016MONTT152
tel-01621440
https://tel.archives-ouvertes.fr/tel-01621440
https://tel.archives-ouvertes.fr/tel-01621440v2/document
https://tel.archives-ouvertes.fr/tel-01621440/file/2016_MKRTCHYAN_archivage.pdf

Éditeur(s) : HAL CCSD American Geophysical Union (AGU)
Résumé : International audience
We use digital elevation models and satellite imagery data completed with field observations to develop an integrated morphotectonic analysis of the anomalous topography of the Central Cordillera of Patagonia between 46 degrees S and 48 degrees S, in a region overlying subducted segments of the Chile Spreading Ridge. This region shows a number of peculiar features, not expected in a normal subduction-related belt located away from a buried spreading center. First, it is characterized by overall short-wavelength topography and highly contrasted reliefs, typical of deeply incised young mountain belts, but surprisingly, also by an average very low elevation of similar to 900 m. Second, the Cordillera lacks central high reliefs; instead, there is a central, depressed domain with average low slope gradients including the deepest point of the study area (300 m below sea level in the bottom of Lake General Carrera/Buenos Aires). This depressed area is flanked by western and eastern regions of higher elevation having opposite general slope dips. To the east, the central Patagonian Cordillera is now separated from the flat plains of the Pampean domain (representing its former piedmont) and several elevated basaltic plateaus (mesetas) by 160 degrees N-180 degrees N trending morphotectonic corridors and the western border scarps of the mesetas. These scarps correspond to neotectonic features controlled by recent vertical faults, mostly active after 3 Ma. Remnants of a former peneplain, the Avellanos surface, are widespread within the entire Cordilleran region. From geological evidence, this peneplain formed between 15 and 4 Ma and was connected originally with the mesetas domain and now is dissected by these corridors. It is shown that a negative inversion related to extensional and strike-slip faulting occurred in the frontal region of the Cordillera at 3 Ma synchronously with the emplacement of magmatic products. Timing of the extensional deformation in central Patagonia is concomitant with the migration at depth of different segments of the South Chile Ridge, which entered the trench at 6 and 3 Ma, respectively, and the consequent opening of a slab window allows asthenospheric hot mantle to reach lithospheric regions. Finally, migration of segments of the Chile Spreading Ridge since 6 Ma triggered regional uplift of the Cordillera followed by limited extension in relation with increased thermal weakening of the crust.
ISSN: 0278-7407

hal-00486334
https://hal.archives-ouvertes.fr/hal-00486334
DOI : 10.1029/2009TC002453

Éditeur(s) : HAL CCSD Elsevier
Résumé : We present comparative field studies in folded areas (Southern France. Moroccan Western Atlas and Abruzzo, Italy) giving new insights into fracture distribution within folded rocks of the shallow brittle crust. We show that the curvature in folds formed in brittle mechanical units is usually accommodated by multiple "dip-domain boundaries" (appearing as curvature discontinuities at fold scale) corresponding to relatively narrow and dense fracture zones, striking parallel or slightly oblique to the fold axis. They separate "dip-domains" where curvature is absent or moderate. It is shown that the dip-domain boundaries (which are obvious in the case of kink folds or box-fold anticlines) are currently present as multiple subtle hinges even when the curvature appears continuous at first sight. The nature of dip-domain boundaries is studied, they often cut through the whole thickness of the mechanical units Their internal structure varies, and a non-exhaustive typology is proposed For each type, an interpretative kinematic scenario shows how the dip-domain boundaries could initiate and develop. We suggest two kinds of origins (1) they could correspond to the reactivation of inherited, along-strike fracture zones (opening-mode fracture concentrations such as big joints, fracture corridors. Inherited faults, etc), (2) they could be created as mechanical instabilities during the fold formation (syn-folding origin), in particular through small reverse faults. In both cases, early zones of weakness localize the dip-domain boundaries, and control the Increase in curvature in association with increasing fracture density within the boundary. Because they represent well-defined vertically and axially persistent sub-seismic fracture zones generally limited to the thickness of the folded unit, dip-domain boundaries could enhance the axial permeability of folded and fractured reservoirs.
ISSN: 0191-8141

hal-00512651
https://hal.archives-ouvertes.fr/hal-00512651
DOI : 10.1016/j.jsg.2010.03.002

Éditeur(s) : HAL CCSD Elsevier Masson
Résumé : International audience
The seismological study of recent seismic crises near Oleron Island confirms the coexistence of an extensional deformation and a transtensive regime in the Atlantic margin of France, which is different from the general western European stress field corresponding to a strike-slip regime. We argue that the switch of the principal stress axes σ1/σ2 in a NW-SE vertical plane is linked with the existence of crustal heterogeneities. Events of magnitude larger than 5 sometimes occur along the Atlantic margin of France, such as the 7 September 1972 (ML = 5.2) earthquake near Oleron island and the 30 September 2002 (ML = 5.7) Hennebont event in Brittany. To test the mechanism of local strain localization, we model the deformation of the hypocentral area of the Hennebont earthquake using a 3D thermo-mechanical finite element code. We conclude that the occurrence of moderate earthquakes located in limited parts of the Hercynian shear zones (as the often reactivated swarms near Oleron) could be due to local reactivation of pre-existing faults. These sporadic seismic ruptures are favoured by stress concentration due to rheological heterogeneities.
ISSN: 1631-0713

hal-00936220
https://hal.archives-ouvertes.fr/hal-00936220
DOI : 10.1016/j.crte.2013.07.004

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
The fitness landscapethe mapping between genotypes and fitnessdetermines properties of the process of adaptation. Several small genotypic fitness landscapes have recently been built by selecting a handful of beneficial mutations and measuring fitness of all combinations of these mutations. Here, we generate several testable predictions for the properties of these small genotypic landscapes under Fisher's geometric model of adaptation. When the ancestral strain is far from the fitness optimum, we analytically compute the fitness effect of selected mutations and their epistatic interactions. Epistasis may be negative or positive on average depending on the distance of the ancestral genotype to the optimum and whether mutations were independently selected, or coselected in an adaptive walk. Simulations show that genotypic landscapes built from Fisher's model are very close to an additive landscape when the ancestral strain is far from the optimum. However, when it is close to the optimum, a large diversity of landscape with substantial roughness and sign epistasis emerged. Strikingly, small genotypic landscapes built from several replicate adaptive walks on the same underlying landscape were highly variable, suggesting that several realizations of small genotypic landscapes are needed to gain information about the underlying architecture of the fitness landscape.
ISSN: 0014-3820

hal-01544760
https://hal.archives-ouvertes.fr/hal-01544760
DOI : 10.1111/evo.12545