Éditeur(s) : HAL CCSD American Geophysical Union (AGU)
Résumé : International audience
[1] The Pyrenees, north of the North Pyrenean fault, display a complex structure involving a succession of peridotite massifs, basement massifs, and mid-Cretaceous to Late Cretaceous basins located in a narrow domain, which was affected by a mid-Cretaceous, preorogenic, high-temperature, low-pressure metamorphism. The Late Cretaceous basins were interpreted either as pull-apart basins formed during transcurrent motion of Iberia relative to Eurasia or as remnants of a larger extensional basin. Recent models support that peridotite massifs result from the exhumation of the mantle during this preorogenic event. The northern boundary of the Agly basement massif shows evidence of ductile deformation of the basal formations of the Agly sedimentary cover. Macroscopic and microscopic kinematics indicators consistent with asymmetry of crystallographic fabrics suggest normal sense of shear and thus suggest detachment, at least partial, of the Mesozoic cover from its basement. Triassic to Early Cretaceous limestones are mylonitic and consistently shows a foliation, a NS- to NE-trending lineation, shear criteria suggesting top-to-the-north shearing and locally boudinage. At the microscopic scale, mylonites are characterized by a very fine grain size, frequently <10 µm. They contain larger, partially recrystallized calcite parent grains and undeformed quartz grains with calcite fringes crystallized in pressure shadows. In these mylonites, calcite systematically shows a weak but well-defined crystallographic-preferred orientations, suggesting HT dislocation creep combined to diffusion creep and possibly grain boundary sliding in the finest fraction of the mylonites. Paleotemperatures determined using Raman spectrometry suggest synkinematic temperature conditions in the range 340-390°C, in good agreement with observed microstructures and calcite CPO. The mylonitic fabric in Mesozoic limestones is folded by EW-trending Pyrenean folds north of the Agly basement massif, attesting that this fabric formed before the Pyrenean orogeny. These data consistently support preorogenic extension under medium-temperature conditions of the northern Agly massif and likely of the massif itself. Since simultaneously (~100 Ma) a mid-Cretaceous basin opened south of the basement massif, we suggest a model of preorogenic exhumation of the Agly massif in response to the regional extension associated to the rotation of Iberia. This model may explain the exhumation of the North Pyrenean massifs during a single preorogenic event that allowed the opening of extensional basins and the exhumation of the lithospheric mantle. All these structures being subsequently reworked during the Pyrenean orogeny.
ISSN: 0278-7407

hal-00852833
https://hal.archives-ouvertes.fr/hal-00852833
DOI : 10.1002/tect.20015

Éditeur(s) : HAL CCSD Springer
Résumé : International audience
Thiswork examines the relevance of the inclusion of ground-based gravity data in the calibration process of a global rainfall-discharge reservoir model. The analysis is performed for the Durzon karst system (Larzac, France). The first part of the study focuses on the hydrological interpretation of the ground-based gravity measurements. The second part of the study investigates further the information content of the gravity data with respect to water storage dynamics modelling.The gravity-derived information is found unable to either reduce equifinality of the single-objective, dischargebased model calibration process or enhance model performance through assimilation.
ISSN: 1866-6280

hal-00812624
https://hal-brgm.archives-ouvertes.fr/hal-00812624
DOI : 10.1007/s12665-012-1856-z

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
Projections of climate change impacts on coral reefs produced at the coarse resolution (~1°) of Global Climate Models (GCMs) have informed debate but have not helped target local management actions. Here, projections of the onset of annual coral bleaching conditions in the Caribbean under Representative Concentration Pathway (RCP) 8.5 are produced using an ensemble of 33 Coupled Model Intercomparison Project phase-5 models and via dynamical and statistical downscaling. A high-resolution (~11 km) regional ocean model (MOM4.1) is used for the dynamical downscaling. For statistical downscaling, sea surface temperature (SST) means and annual cycles in all the GCMs are replaced with observed data from the ~4-km NOAA Pathfinder SST dataset. Spatial patterns in all three projections are broadly similar ; the average year for the onset of annual severe bleaching is 2040–2043 for all projections. However, downscaled projections show many locations where the onset of annual severe bleaching (ASB) varies 10 or more years within a single GCM grid cell. Managers in locations where this applies (e.g., Florida, Turks and Caicos, Puerto Rico, and the Domini-can Republic, among others) can identify locations that represent relative albeit temporary refugia. Both downscaled projections are different for the Bahamas compared to the GCM projections. The dynamically downscaled projections suggest an earlier onset of ASB linked to projected changes in regional currents, a feature not resolved in GCMs. This result demonstrates the value of dynamical downscaling for this application and means statistically downscaled projections have to be interpreted with caution. However, aside from west of Andros Island, the projections for the two types of downscaling are mostly aligned; projected onset of ASB is within AE10 years for 72% of the reef locations.
ISSN: 1354-1013

Droits : http://creativecommons.org/licenses/by-nc/
hal-01223492
https://hal-univ-perp.archives-ouvertes.fr/hal-01223492
https://hal-univ-perp.archives-ouvertes.fr/hal-01223492/document
https://hal-univ-perp.archives-ouvertes.fr/hal-01223492/file/Hooidonk_et_al-2015-Global_Change_Biology.pdf
DOI : 10.1111/gcb.12901

Éditeur(s) : HAL CCSD
Résumé :  
For a comprehensive evaluation of human influences on the genetic system, the simulation model EGO-GENE was developed. The model combines population genetic and population dynamic processes with forest growth models. The dynamics of genetic structures (single locus and multilocus genotypes up to 200 loci) can be simulated. Spatial and temporal genetic dynamics are included in the model. Overlapping or separated generations can be created and different modes of mating systems can be implemented. The model can be run with empirical and fictitious input data. The simulated genetic structures can be directly analysed with established genetic analysis programmes. An example demonstrates the use of the model far validation of interactions among components of the mating system. Another example demonstrates the applicability of the model in decision-making for seed sampling strategies. The genetic differences between the adult trees and the harvested seeds and the danger of genetic drift regarding to different seed sampling strategies are investigated by use of the genetic distance and the reproductively effective population size.
Silvae genetica

hal-01032083
https://hal.archives-ouvertes.fr/hal-01032083

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The Borborema Province of northeastern Brazil is divided into three main domains: northern, central, and southern. Several U-Pb zircon ages of plutons and orthogneisses became available in the recent years in the central and northern domains, but similar results are scarce in the southern domain. This study reports U-Pb dates for single zircon grains from one orthogneiss (Jupi orthogneiss) and two plutons (Cachoeirinha syenitic pluton and Cabanas granite) south of the East Pernambuco shear zone system (EPSZ). The results provide geochronological constraints on the timing of deformation and magmatism in this part of the southern domain and allow correlations with the central domain. The Jupi orthogneiss was emplaced and deformed during development of the regional flat-lying foliation. A Pb-206/U-238 weighted apparent mean age of 606 +/- 8 Ma is interpreted as the crystallization age of the protolith of the orthogneiss and consequently the age of high-grade Brasiliano metamorphism. The NNE-trending Cachoeirinha pluton is only locally affected by strike-slip deformation, whereas the ENE-trending Cabanas granite is intensely affected by deformation related to the EPSZ. The 587 8 Ma and 573 4 Ma ages of the Cachoeirinha pluton and Cabanas granite, respectively, bracket the main period of activity of the EPSZ. Tectonomagmatic activity in the study area is similar to the age of Brasiliano events in the central domain, north of the EPSZ. In addition, xenocrystic zircons in the Jupi orthogneiss and Cabanas granite are interpreted as inherited from Paleoproterozoic source rocks, suggesting the presence of widespread reworked old crust in the southern domain, similar to the central domain. These results support the idea that the central and southern domains belonged to the same crustal block before the onset of the Brasiliano orogeny.
ISSN: 0895-9811

hal-00411394
https://hal.archives-ouvertes.fr/hal-00411394
DOI : 10.1016/j.jsames.2007.06.003

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : The Oman ophiolite consists of several massifs cropping out along a 500 km long band trending NW-SE along the coast of Oman; it is one of the best exposed sections of oceanic crust and mantle in the world. There is a gradient in igneous processes and composition in the ophiolite, with the northern massifs recording a polygenetic igneous history involving an increasingly important subduction component, whereas the southern massifs were formed primarily via a mid-ocean ridge basalt (MORB)-like, single-stage process at a submarine spreading ridge. In this study we use geochemical data from Wadi Tayin, which is one of the southern massifs of the Oman ophiolite, to constrain the composition and genesis of oceanic crust and upper mantle. The Wadi Tayin harzburgites are residues of partial melting that are as depleted as the most depleted mid-ocean ridge peridotites. They have low middle- to heavy rare earth element ratios, most probably reflecting melting close to and beyond the exhaustion of clinopyroxene. Like many abyssal peridotites, the Wadi Tayin samples show enrichment in highly incompatible elements, giving rise to U-shaped MORB-normalized trace element patterns. We favor the idea that this is caused by enrichment of highly incompatible elements along grain boundaries in peridotite, which may be the result of near-equilibrium partitioning between grain boundaries and grain interiors, rather than disequilibrium processes. Equilibrium partitioning between crystals and grain boundaries during melting and melt extraction is also our preferred explanation for ubiquitous high Pb contents relative to Ce and La in our samples as well as in most abyssal peridotites. The Wadi Tayin samples record substantial variability in terms of osmium isotopic composition and platinum group element (PGE) concentrations. The more radiogenic nature of the dunites and impregnated peridotites compared with the residual harzburgites may be due to relatively high Os-187/Os-188 in melt transported through the dunites. The presence of residual peridotites with whole-rock osmium isotopic compositions less radiogenic than MORB may be explained by melting of a veined (upwelling) mantle forming mixed melts in which much of the Os derives from veins with high Re/Os in a matrix of previously depleted peridotite. An important result of this study is that the shallowest samples are refertilized (i.e. anomalously enriched in incompatible elements), and record relatively high metamorphic closure temperatures. These observations suggest that migrating melt underwent crystallization during rapid cooling in the uppermost mantle during and immediately after ridge magmatism. A variety of geothermometers all yield the result that the stratigraphically highest harzburgites equilibrated at higher temperature than the deeper ones. The systematic decrease in closure temperature with increasing depth below the Moho transition zone probably reflects systematic variation in cooling rate as a function of depth in the mantle section. We hypothesize that the refertilization and higher closure temperatures recorded by the uppermost mantle samples are linked. More rapid cooling led to higher closure temperatures, and to partial crystallization of migrating melts in the shallowest part of the mantle section, yielding slightly elevated abundances of elements such as Ca and Na, and incompatible trace elements.
ISSN: 0022-3530

hal-00456056
https://hal.archives-ouvertes.fr/hal-00456056
DOI : 10.1093/petrology/egp077

Éditeur(s) : HAL CCSD American Physical Society
Résumé : International audience
We investigate a class of granular materials characterized by the possibility of interlocking between the particles. The interlocking is modeled by its effect through rolling resistance depending on relative rotation and normal force at the contact points and involving a single parameter analogous to the sliding friction coefficient. The model, which is introduced in the framework of the contact dynamics, method, is applied to simulate the simple shear of a large granular sample. We present a detailed analysis regarding the influence of rolling and sliding friction parameters on the macroscopic response in terms of shear strength, fabric properties, and force transmission. Interestingly, two distinct regimes can be distinguished in which the steady-state shear strength is controlled by either rolling resistance or sliding friction. The relative contributions of rolling and sliding contacts to the shear strength are consistent with the same two regimes. Interlocking strongly affects the force network by enhancing the arching effect and thus increasing the relative importance of weak contact forces and torques, which is reflected in a decreasing power-law probability distribution of the contact forces and torques below the mean. Due to the combined effect of friction and interlocking, the force-carrying backbone takes an increasingly columnar aspect involving a low fraction of particles. Our data suggest that the nature of the weak contact network is strongly affected by the formation of these columns of particles which do not need to be propped laterally. In particular, in the limit of high rolling resistance and sliding friction, the role of the weak network of contacts is no longer to prop the force chains, but, like the strong contact network, to actively sustain the deviatoric load imposed on the system.
ISSN: 1539-3755

hal-00412020
https://hal.archives-ouvertes.fr/hal-00412020
DOI : 10.1103/PhysRevE.78.021301

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
ABSTRACT: BACKGROUND: The amount of lead in the environment has decreased significantly in recent years, and so did exposure. However, there is no known safe exposure level and, therefore, the exposure of children to lead, although low, remains a major public health issue. With the lower levels of exposure, it is becoming more difficult to identify lead sources and new approaches may be required for preventive action. This study assessed the usefulness of lead isotope ratios for identifying sources of lead using data from a nationwide sample of French children aged from six months to six years with blood lead levels (B-Pb) [greater than or equal to] 25 ug/L. METHODS: Blood samples were taken from 125 children, representing about 600,000 French children; environmental samples were taken from their homes and personal information was collected. Lead isotope ratios were determined using quadrupole ICP-MS (inductively coupled plasma - mass spectrometry) and the isotopic signatures of potential sources of exposure were matched with those of blood in order to identify the most likely sources. RESULTS: In addition to the interpretation of lead concentrations, lead isotope ratios were potentially of use for 57% of children aged from six months to six years with blood lead level [greater than or equal to] 25 ug/L (7% of overall children in France, about 332,000 children), with at least one potential source of lead and sufficiently well discriminated lead isotope ratios. Lead isotope ratios revealed a single suspected source of exposure for 32% of the subjects and were able to eliminate at least one unlikely source of exposure for 30% of the children. CONCLUSIONS: In France, lead isotope ratios could provide valuable additional information in about a third of routine environmental investigations.
ISSN: 1476-069X

inserm-00624817
http://www.hal.inserm.fr/inserm-00624817
http://www.hal.inserm.fr/inserm-00624817/document
http://www.hal.inserm.fr/inserm-00624817/file/1476-069X-10-75.pdf
DOI : 10.1186/1476-069X-10-75

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Background & Aims: The severity of liver diseases is exacerbated by the death of hepatocytes, which can be induced by the sensing of pathogen associated molecular patterns (PAMPs) derived from the gut microbiota. The molecular mechanisms regulating these cell death pathways are poorly documented. In this study, we investigated the role of the receptor interacting protein kinase 1 (RIPK1), a protein known to regulate cell fate decisions, in the death of hepatocytes using two in vivo models of PAMP-induced hepatitis. Methods: Hepatitis was induced in mice by independent injections of two different bacterial PAMPs: lipopolysaccharide (LPS) and unmethylated CpG oligodeoxynucleotide (CpG-DNA) motifs. The role of RIPK1 was evaluated by using mice specifically lacking RIPK1 in liver parenchymal cells (Ripk1(LPC-KO)). Administration of liposome-encapsulated clodronate served to investigate the role of Kupffer cells in the establishment of the disease. Etanercept, a tumor necrosis factor (TNF)-decoy receptor, was used to study the contribution of TNF-alpha during LPS-mediated liver injury. Results: Whereas RIPK1 deficiency in liver parenchymal cells did not trigger basal hepatolysis, it greatly sensitized hepatocytes to apoptosis and liver damage following a single injection of LPS or CpG-DNA. Importantly, hepatocyte death was prevented by previous macrophage depletion or by TNF inhibition. Conclusions: Our data highlight the pivotal function of RIPK1 in maintaining liver homeostasis in conditions of macrophage-induced TNF burst in response to PAMPs sensing. Lay summary: Excessive death of hepatocytes is a characteristic of liver injury. A new programmed cell death pathway has been described involving upstream death ligands such as TNF and downstream kinases such as RIPK1. Here, we show that in the presence of LPS liver induced hepatic injury was due to secretion of TNF by liver macrophages, and that RIPK1 acts as a powerful protector of hepatocyte death. This newly identified pathway in the liver may be helpful in the management of patients to predict their risk of developing acute liver failure. (C) 2017 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
ISSN: 0168-8278

hal-01532060
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01532060
DOI : 10.1016/j.jhep.2017.01.005
PUBMED : 28088582

Éditeur(s) : HAL CCSD Coastal Education and Research Foundation
Résumé : Nearshore bars are generally present on sandy coasts and play a significant role in wave breaking and sediment exchange between beach and shoreface. The study area is located on the Languedoc-Roussillon coast in the Gulf of Lions (southern part of the French Mediterranean coast). This microtidal environment is classified as a wave-dominated coast. The sand coast displays different bar systems (single or multiple; straight or crescentic). The alongshore variability of bar morphology in the nearshore zone was investigated in August 2009 during one week, using a topo-bathymetric LIDAR data set (300 km(2)). LIDAR makes it possible to cover a large area in a very short time with a high resolution. The topo-bathymetric LIDAR offers the added benefit of morphological information about the beach-sea transition in very shallow water (below I in), data often difficult if not impossible to obtain with traditional techniques. The purpose of this paper is 1) to depict the distribution of bars and their characteristics along the 180 km coast of the Gulf of Lions; 2) to update the classifications of sand bars typologies in Languedoc-Roussillon; 3) to pay particular attention to the description of the intricate inner system. Globally, cross-shore distribution of subtidal morphologies is characterized by both an outer and an inner system. The outer system is crescent-shaped in the south and straight in the northern part with a distinctive regional delimitation. The inner system comprises an inner bar and, near the coast, a complex fluctuating bar called Low Bar Beach (LBB). Several intermediate states were identified and added to the new classification proposed in this paper. These results clearly emphasize the importance of LIDAR technology for a better understanding of bar behaviour and single and/or multi-bar beach organisation.
ISSN: 0749-0208

hal-00783187
https://hal.archives-ouvertes.fr/hal-00783187

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Based on new photographs of the wound, Tirard et al. (2015) tried to demonstrate that the shark involved in a fatal attack on a human in Lifou in 2007 had homodont teeth and that it sawed the femur instead of directly cutting it, promoting the hypothesis that it was a tiger shark instead of a white shark. They also contested the data provided by the direct witness of the attack about the behaviour of the shark, specific to this former species. The evidences they provide are not convincing and, based on the absence of tissue loss and description of a jumping behaviour, we still believe that it was a single bite-and-spit attack by a white shark.
ISSN: 1752-928X

hal-01310536
https://hal-univ-perp.archives-ouvertes.fr/hal-01310536
DOI : 10.1016/j.jflm.2016.03.004

Éditeur(s) : HAL CCSD G.M.P.C.a/Presses universitaires de Rennes
Résumé : Magnetic measurements (magnetic susceptibility at low and high frequency, isothermal and anhysteretic remanent magnetizations, magnetic susceptibility according to the temperature and hysteresis loop) were carried out on samples taken in the filling of Caverna delle Manie (Arma delle Manie) located in Ligurie, Italy. The filling of the site, dating from upper Pleistocene and Holocene, is characterized in its upper part by an alternance of carbonated concretions, stalagmitic floors and clays, and in its lower part by an sandy-silty-clay deposit. The results of the magnetic study reveal the abundance of magnetic grains of secondary origin (magnetite and maghemite), and more particularly in the upper part of the filling. The grains of superparamagnetic size (SP) dominate, followed by those of multi-domain (MD) and single-domain size (SD). The latter have a low coercitive force. Some hearths were located within the filling thanks to their color, with the presence of coal and the strong values of the various magnetic parameters.
Des mesures magnétiques (susceptibilité magnétique à basse et haute fréquence, aimantation rémanente isotherme et anhystérétique, susceptibilité magnétique en fonction de la température et cycle d'hystérésis) ont été réalisées sur des échantillons prélevés dans le remplissage de la Caverna delle Manie (Arma delle Manie) située en Ligurie Italienne. Le remplissage du site, d'âge Pléistocène supérieur et Holocène, se caractérise dans sa partie supérieure par l'alternance de concrétions carbonatées, de planchers stalagmitiques, et d'argiles; et dans sa partie inférieure par un dépôt sablo-limono-argileux. Les résultats de l'étude magnétique révèlent l'abondance de grains magnétiques d'origine secondaire (magnétite et maghémite). Cette abondance est plus marquée dans la partie supérieure du remplissage. Les grains de taille superparamagnétique (SP) dominent, suivi par ceux de taille poly-domaine (PD) et mono-domaine (MD). Ces derniers ont un champ coercitif faible. Quelques foyers ont été repérés au sein du remplissage grâce à leur couleur, à la présence de charbon et aux fortes valeurs des différents paramètres magnétiques.
ISSN: 1960-1360

hal-00653405
https://hal.archives-ouvertes.fr/hal-00653405

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The eastern part of the Cordillera Occidental of Ecuador comprises thick buoyant oceanic plateaus associated with island-arc tholeiites and subduction-related calc-alkaline series, accreted to the Ecuadorian Continental Margin from Late Cretaceous to Eocene times. One of these plateau sequences, the Guaranda Oceanic Plateau is considered as remnant of the Caribbean–Colombian Oceanic Province (CCOP) accreted to the Ecuadorian Margin in the Maastrichtien. Samples studied in this paper were taken from four cross-sections through two arc-sequences in the northern part of the Cordillera Occidental of Ecuador, dated as (Río Cala) or ascribed to (Macuchi) the Late Cretaceous and one arc-like sequence in the Chogòn-Colonche Cordillera (Las Orquídeas). These three island-arcs can clearly be identified and rest conformably on the CCOP. In all four localities, basalts with abundant large clinopyroxene phenocrysts can be found, mimicking a picritic or ankaramitic facies. This mineralogical particularity, although not uncommon in island arc lavas, hints at a contribution of the CCOP in the genesis of these island arc rocks. The complete petrological and geochemical study of these rocks reveals that some have a primitive island-arc nature (MgO values range from 6 to 11 wt.%). Studied samples display marked Nb, Ta and Ti negative anomalies relative to the adjacent elements in the spidergrams characteristic of subduction-related magmatism. These rocks are LREE-enriched and their clinopyroxenes show a tholeiitic affinity (FeOT–TiO2 enrichment and CaO depletion from core to rim within a single crystal). The four sampled cross-sections through the island-arc sequences display homogeneous initial Nd, and Pb isotope ratios that suggest a unique mantellic source for these rocks resulting from the mixing of three components: an East-Pacific MORB end-member, an enriched pelagic sediment component, and a HIMU component carried by the CCOP. Indeed, the ankaramite and Mg-basalt sequences that form part of the Caribbean-Colombian Oceanic Plateau are radiogenically enriched in 206Pb/204Pb and 207Pb/204Pb and contain a HIMU component similar to that observed in the Gorgona basalts and Galápagos lavas. The subduction zone that generated the Late Cretaceous arcs occurred far from the continental margin, in an oceanic environment. This implies that no terrigenous detrital sediments interacted with the source at this period. Thus, the enriched component can only result from the melting of subducted pelagic sediments. We have thus defined the East-Pacific MORB, enriched (cherts, pelagic sediments) and HIMU components in an attempt to constrain and model the genesis of the studied island-arc magmatism, using a compilation of carefully selected isotopic data from literature according to rock age and paleogeographic location at the time of arc edification. Tripolar mixing models reveal that proportions of 12–15 wt.% of the HIMU component, 7–15 wt.% of the pelagic sediment end-member and 70–75 wt.% of an East-pacific MORB end-member are needed to explain the measured isotope ratios. These surprisingly high proportions of the HIMU/CCOP component could be explained by the young age of the oceanic plateau (5–15 Ma) during the Late Cretaceous arc emplacement. The CCOP, basement of these arc sequences, was probably still hot and easily assimilated at the island-arc lava source.
ISSN: 0895-9811

insu-00353692
https://hal-insu.archives-ouvertes.fr/insu-00353692
DOI : 10.1016/j.jsames.2008.06.003

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
The brown algal genus Padina (Dictyotales, Phaeophyceae) is distributed worldwide in tropical and temperate seas. Global species diversity and distribution ranges, however, remain largely unknown. Species-level diversity was reassessed using DNA-based, algorithmic species delineation techniques based on cox3 and rbcL sequence data from 221 specimens collected worldwide. This resulted in estimates ranging from 39 to 61 putative species (ESUs), depending on the technique as well as the locus. We discuss the merits, potential pitfalls, and evolutionary and biogeographic significance of algorithmic species delineation. We unveil patterns whereby ESUs are in all but one case restricted to either the Atlantic or Indo-Pacific Ocean. Within ocean basins we find evidence for the vast majority of ESUs to be confined to a single marine realm. Exceptions, whereby ESUs span up to three realms, are located in the Indo-Pacific Ocean. Patterns of range-restricted species likely arise by repeated founder events and subsequent peripatric speciation, hypothesized to dominate speciation mechanisms for coastal marine organisms in the Indo-Pacific. Using a three-gene (cox3, psaA and rbcL), relaxed molecular clock phylogenetic analysis we estimated divergence times, providing a historical framework to interpret biogeographic patterns.
ISSN: 0022-3646

hal-01545323
https://hal.archives-ouvertes.fr/hal-01545323
DOI : 10.1111/jpy.12027

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
Geochronological, mineralogical, and geochemical analyses have been focussed on the Mont-Loze're- Borne plutonic complex and surrounding rocks (Ce'vennes, French Massif Central) in which B-W-Sn and As-Au-Sb mineralization is encountered. Two main results are highlighted: (1) the existence of a 301-306 Ma magmatohydrothermal event unrelated to the emplacement of the Pont-de-Montvert-Borne plutonic body at 316 Ma; (2) the magmatic and hydrothermal features are strongly associated, both in time and in space, thus demonstrating an intimate connection between mineralizing processes and magmatism in this part of the French Massif Central. We also show that mineralization and associated hydrothermal occurrences do not correspond to a simple and single geochemical signature and that a contamination model must be invoked in order to account for the complexity of isotopic results. This study demonstrates that the application of the O and H isotopic signatures as tracers of the source and nature of fluids in an orogenic context requires some specific care. Finally, a model of the tectonic-magmatic- hydrothermal evolution of the study area is suggested in which we discuss two alternative scenarios. The first one implies the existence of two different hydrothermal/ mineralizing events (Bo-W-Sn and As-Au-Sb ones). The second one suggests the same source for all hydrothermal and mineralized structures.
ISSN: 1437-3254

insu-00576546
https://hal-insu.archives-ouvertes.fr/insu-00576546
https://hal-insu.archives-ouvertes.fr/insu-00576546/document
https://hal-insu.archives-ouvertes.fr/insu-00576546/file/Chauvet-InternationalJournalEarthSciences-2012.pdf
DOI : 10.1007/s00531-011-0639-1

Éditeur(s) : HAL CCSD
Résumé : Several major earthquakes have struck the 2500 km long Himalayan range during the past century. However, both the maximum size of such earthquakes and the probability of occurrence of a magnitude 9 megaquake are still a mater of debate. In this framework it is of key importance to investigate the lateral segmentation of the Himalayan arc in order to deepen our understanding of the mechanisms that control such events as well as their extents. Besides the remarkably uniform tectonic set-up and the fact that most studies on the Himalayas have focused on Central Nepal, several indications of along strike changes can be gathered.This thesis brings new constraints on lateral variations of crustal structure and of deformation between western Nepal (~80°E) and eastern Bhutan (~92°E).The first part of this thesis focuses on the lateral variations of crustal structure. In the past three years we have carried out four land gravity campaigns. We have established 366 new gravity measurement points to fill the data gaps in central and western Nepal as well as in Bhutan. This new dataset, together with available seismological data, is used to constrain thermo-mechanical models of the bending of the India plate underneath the Himalayas. While the inferred crustal geometry does not exhibit major along-strike variations over central and eastern Nepal, the shorter wavelength flexure of the lithosphere in Bhutan is associated with a weaker upper mantle rheology.The second part focuses on the lateral variations of recent deformation in the Himalayas. Fifteen years of paleoseismological investigations have extended the catalogue of major Himalayan events over the last millennium. Combining these information with secular loading, we assess the spatial and temporal stress changes on the Main Himalayan Thrust along the orogen over the last nine centuries. Our calculations indicate that inter-seismic loading has now nearly overcome the Coulomb stress decrease caused by the great ~1100 medieval earthquake. Our results also point out that the 1897 Shillong plateau earthquake does not have a major influence on the stress accumulated on the Main Himalayan Thrust since then. In order to better characterize active tectonics in the Bhutan Himalayas where no studies were done so far, we carried out a morphotectonic analysis in the south-central part of the kingdom. We show that the same amount of Holocene deformation is accommodated on the frontal thrust in Bhutan as on the neighbouring portions of the Himalayan arc. We also find evidences for two major (M>8) earthquakes on this thrust in the Bhutan Himalayas during the last millennium. Our results therefore show that Bhutan cannot be considered as a seismic gap. They also challenge the interpretation of one single ~1100 medieval mega-event that would have ruptured the Main Frontal Thrust from central Nepal to eastern Bhutan.
Au cours du dernier siècle, plusieurs séismes majeurs ont affecté l'Himalaya. Cependant, la taille maximale de ces événements et la probabilité d'occurrence de méga-séismes avec des magnitudes proches de 9 sont toujours matière à débat. L'étude de la segmentation de l'arc Himalayen est donc primordiale afin de comprendre les mécanismes qui contrôlent ces séismes ainsi que leur extension spatiale. La compréhension du cycle sismique en Himalaya est aujourd'hui essentiellement basée sur des études menées au Népal central, ce qui limite notre connaissance de son fonctionnement tri-dimensionnel. Ce travail de thèse permet d'apporter de nouvelles contraintes sur les variations latérales de la déformation crustale dans la zone comprise entre l'ouest Népal (~80°E) et l'est Bhoutan (~92°E). La première partie de cette thèse est consacrée à l'étude des variations latérales de la structure lithosphérique. Quatre campagnes gravimétriques ont été réalisées entre 2010 et 2012. Elles ont permis d'étendre le réseau gravimétrique Népalais jusqu'à l'ouest Népal et d'établir le premier réseau gravimétrique Bhoutanais. Ce nouveau jeu de données, combiné avec les données sismologiques disponibles, permet de contraindre des modèles thermo-mécaniques de la flexure de la plaque Indienne sous l'Himalaya. Les résultats suggèrent qu'il n'existe pas de variations latérales majeures du comportement mécanique de la lithosphère Indienne entre le centre et l'est Népal contrairement au Bhoutan où une rigidité flexurale plus faible est nécessaire pour expliquer les données.La deuxième partie de cette thèse est consacrée à l'étude des variations latérales des déformations récentes dans le prisme Himalayen. Les études paléosismologiques menées depuis 15 ans en Himalaya ont permis d'étendre le catalogue des événements majeurs sur le dernier millénaire. En intégrant à la fois les contraintes disponibles sur ces séismes majeurs et le chargement séculaire, nous étudions les variations spatiales et temporelles de l'état de contrainte du chevauchemlent Himalayen principal le long de l'arc. Nos calculs montrent que même dans la cas où un méga-séisme se serait produit en ~1100 en Himalaya, le chargement séculaire a quasiment compensé la chute de contrainte associée. Les modèles montrent aussi que le séisme du Shillong ne joue pas un rôle majeur sur les contraintes accumulées sur le chevauchement Himalayen depuis 1897 au niveau du Bhoutan. Enfin, nous présentons les premières contraintes sur la tectonique active au Bhoutan. L'étude morphotectonique réalisée au centre du Sud-Bhoutan a permis de montrer que la majeure partie de la déformation Holocène est accommodée au niveau du front Himalayen, comme au Népal. Nous montrons aussi des évidences de ruptures de surface avec des décalages verticaux de plusieurs mètres associés à deux séismes majeurs sur le dernier millénaire. Ces évidences remettent en cause l'interprétation d'un méga-séisme en ~1100.
https://tel.archives-ouvertes.fr/tel-01002381

NNT : 2013MON20074
tel-01002381
https://tel.archives-ouvertes.fr/tel-01002381
https://tel.archives-ouvertes.fr/tel-01002381/document
https://tel.archives-ouvertes.fr/tel-01002381/file/35970_BERTHET_2013_archivage_cor.pdf

Éditeur(s) : HAL CCSD
Résumé : The ovary is not solely the unique source of oocytes necessary for fertilization but also a crucial conductor of endocrine regulations of the reproductive system. In the fetal ovary, oocytes grouped in clusters are surrounded by somatic pre-granulosa cells, altogether delineated by a basement membrane and constituting ovarian cords. The formation of the definitive ovarian functional units requires their fragmentation into follicles formed by a single oocyte surrounded by granulosa cells and delineated by a basement membrane. This partitioning occurs within a tiny period and is dependent on the correct timing of the meiotic process, on an apoptotic wave that specifically targets oocytes and the remodelling of the basement membrane. Follicle formation is a crucial event of ovarian development because the follicle stock formed at the end of this process is non-renewable. Therefore, any disturbance of this process can lead to reproductive abnormalities in adulthood. Recent data on endocrine disruptors displaying estrogenic activity have involved the fragile estrogenic homeostasis in the process. We aimed at better understanding how the endogen estrogen 17b-estradiol (E2) contributes to follicle formation. To assess it, Sprague-Dawley rats were treated with E2 at different doses during follicle formation, /i.e./ in the 3 days following birth. We show that although this treatment impairs the development of the hepatic and ovarian detoxification systems, the female neonate is able to increase its estrogen clearance capabilities. Nevertheless, E2 treatment within this critical period triggers a dose-dependent decrease of oocyte number per ovary. Regardless of the E2 dose, puberty is advanced. All treated females are at least transiently fertile, yet these reproductive capabilities rapidly decline. A high (10 µg/day) dose of E2 leads to a secondary infertility characterized by anovulation that probably result from a dysfunction of the whole reproductive tract. By contrast, a lower (0.1 µg/day) dose of E2, that does not significantly modify neonatal oocyte survival, leads to a progressive reproductive senescence likely due to ovarian failure. Long-term troubles may originate from precocious E2 impact on the ovary since it disturbs ovarian transcriptome and produces many lesions on ovarian cell DNA.
L'ovaire est au cœur de la physiologie de la reproduction féminine. Il est à la fois à l'origine des ovocytes nécessaires à la fécondation et acteur des régulations endocrines du système reproducteur. Les ovocytes de l'ovaire fœtal sont groupés en amas bordés de cellules somatiques et d'une membrane basale, formant les cordons ovariens. Ces cordons ovariens se fragmentent pour former les follicules ovariens: un ovocyte bordé de cellules somatiques et d'une membrane basale. Cette fragmentation se déroule sur une courte période (/in utero/ chez la femme et juste après la naissance chez les rongeurs) et fait intervenir une vague de mort cellulaire programmée touchant les ovocytes pendant leur méiose et un remodelage de la membrane basale. La formation des follicules est une période cruciale du développement ovarien puisque le stock de follicules formés à l'issue de ce processus est non renouvelable. Son altération peut donc être à l'origine de troubles de la fonction de reproduction chez le futur adulte. Il existe une fragile homéostasie œstrogénique en place au moment de la formation folliculaire: chez la femme, l'ovaire se développe /in utero/, sous l'influence des œstrogènes circulants maternels et la production ovarienne fœtale. Chez les rongeurs, les follicules se forment lors de la levée de l'imprégnation hormonale maternelle au moment de la naissance. Nous avons souhaité comprendre comment le 17b-œstradiol (E2), œstrogène endogène, pouvait contribuer à la mise en place des follicules. Pour cela, des rattes Sprague-Dawley ont été traitées pendant la période de formation des follicules avec de l'E2 à différentes doses entre 0.01 et 10 µg/jour. Nos travaux démontrent que le traitement de rattes par des œstrogènes entre leur naissance et 3 jours induit une réduction dose-dépendante de leur nombre d'ovocytes. Bien que le traitement entrave le développement normal du système de détoxication hépatique et ovarien, l'animal est capable d'accroître ses capacités d'élimination des œstrogènes. Ces capacités sont toutefois insuffisantes pour bloquer les effets du traitement. Quelle que soit la dose d'E2 utilisée (0.1 ou 10 µg/jour), la puberté est plus précoce chez les femelles exposées mais toutes sont fertiles, au moins transitoirement. Cependant le traitement induit une dégradation rapide des capacités reproductives. L'E2 modifie la dynamique folliculaire chez l'adulte, longtemps après l'arrêt du traitement. Si une forte dose d'E2 réduit la survie des ovocytes lors de la formation des follicules et conduit à une infertilité secondaire due à un dysfonctionnement général du tractus reproducteur, une dose faible n'affecte pas la survie des ovocytes à court terme mais conduit à une sénescence reproductive précoce vraisemblablement d'origine ovarienne. L'origine de ces troubles pourrait résider dans les effets précoces de l'exposition à E2 : cette molécule altère le transcriptome ovarien et induit de nombreuses lésions de l'ADN des cellules ovariennes.
https://tel.archives-ouvertes.fr/tel-00953657

NNT : 2013REN1S107
tel-00953657
https://tel.archives-ouvertes.fr/tel-00953657
https://tel.archives-ouvertes.fr/tel-00953657/document
https://tel.archives-ouvertes.fr/tel-00953657/file/CHALMEY_Clementine.pdf

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : This study focuses on the petrology, geochronology and thermochronology of metamorphic rocks within the northern Menderes Massif in western Turkey. Metasediments belonging to the cover series of the Massif record pervasive amphibolite-facies metamorphism culminating at ca. 625–670 °C and 7–9 kbars. U–Th–Pb in situ ages on monazite and allanite from these metapelites record crustal thickening and nappe stacking associated with the internal imbrication of the Anatolide–Taurides platform during the Eocene. In addition, new 39Ar/40Ar single muscovite grain analyses on deformed rocks were performed in three localities within the northern Menderes Massif and ages range from 19.8 to 25.5 Ma. These mylonites may be related to both well-known detachments, Simav to the north and Alaşehir to the south, which accommodate Oligo–Miocene exhumation of the Menderes core complex. U–Th–Pb data on monazite grains (22.2 ± 0.2 Ma) from migmatites emplaced within the Simav detachment confirm these ages.
ISSN: 1437-3254

hal-01355967
https://hal.archives-ouvertes.fr/hal-01355967
DOI : 10.1007/s00531-015-1271-2

Éditeur(s) : HAL CCSD
Résumé : International audience
Background: In French Guiana, a recent study has shown that a major part of the histoplasmosis incidence temporal fluctuations could be explained by climatic factors and thus postulated that disseminated histoplasmosis cases could be in a large proportion due to new infections. The description of the seasonal pattern of histoplasmosis could potentially help to test this new hypothesis. Patients and methods: A study using prospective data from the French Hospital Database for HIV was conducted in order to determine seasonal variations of the incidence of first cases of disseminated histoplasmosis in HIV persons in Cayenne, French Guiana. Single failure Cox proportional hazards models were used. Results: After adjusting for CD4 counts and antiretroviral treatment, the incidence of disseminated histoplasmosis was significantly higher during the Short Wet Season-Long Dry Season than during the Short Dry Season-Long Wet Season (Adjusted Hazard ratio 1.7 (1.1-2.5), P= 0.01). Conclusion: This result gives both valuable epidemiologic information to clinicians and a supplementary argument in favour of the hypothesis that an important proportion of cases were due to recent exposure. Therefore, the use of a primary prophylaxis must be discussed in French Guiana.
J AIDS Clinic Res

Droits : info:eu-repo/semantics/OpenAccess
inserm-00915009
http://www.hal.inserm.fr/inserm-00915009
http://www.hal.inserm.fr/inserm-00915009/document
http://www.hal.inserm.fr/inserm-00915009/file/2012_Hanf_-_Disseminated_Histoplasmosis_seasonal_incidence_variations_a_supplementary_argument_for_recent_infection.pdf
DOI : 10.4172/2155-6113.1000175

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The aim of this paper is to prove that the framework of generalized functions of Sobolev type is more suitable to pose and solve some PDEs problems with very irregular data, than the one introduced by J.-F. Colombeau, when ${mathcal{C}}^{infty}$ estimates are not available or out of reach. In such type of algebras, one shows the existence and some qualitative properties of solutions for problems appearing in the mathematical modelisation of oil activities.
Journal of Mathematical Analysis and applications

hal-00685042
https://hal.archives-ouvertes.fr/hal-00685042
DOI : 10.1016/j.jmaa.2011.07.063