Éditeur(s) : Journées du département Ressources Biologiques et Environnement
Résumé : L'aquaculture est une activité importante du paysage économique de la Nouvelle-Calédonie., La crevette Bleue du Pacifique, Litopenaeus stylirostris est aujourd’hui l’espèce cible, élevée en semi-intensif, dans des bassins de terre de 4 à 10 hectares. Une coloration orange prononcée au niveau des branchies, comparable à celle observée suite à un stress hypoxique alors qu’aucun déficit en oxygène n’est constaté, est apparue récemment engendrant une décote du produit à la vente et donc un risque économique supplémentaire pour cette filière déjà fragilisée par des mortalités à vibrioses. Le phénomène se déclare à un poids moyen des animaux compris entre 10 et 18 g pour une durée moyenne d’élevage de 70 jours. L'intensité de la couleur évolue avec le stade de mue, les animaux au stade de pré-mue étant les plus touchés. Cette coloration disparaît avec la mue pour réapparaître au cycle suivant. Différentes techniques ont montré qu'elle était due à un dépôt d'oxyde de fer à la surface des tissus. Une micro-analyse par MEB montre un taux de fer dissous jusqu’à dix fois supérieur dans les branchies orange par rapport aux branchies non colorées ainsi qu'une répartition non homogène de ce métal. Par ailleurs une colonisation de cette surface branchiale par des bactéries est visible indiquant une implication potentielle de ces microorganismes dans le processus de précipitation du fer et donc dans l'apparition de cette coloration. De très fortes concentrations en fer dissous, jusqu'à 70 µM, ont été mesurées dans les eaux interstitielles des sédiments suggérant une origine environnementale à ce phénomène. Les prochains travaux devraient se focaliser sur (1) les conditions de milieu favorables à la production de fer dissous dans les sédiments, (2) les mécanismes impliqués dans sa précipitation à la surface des branchies et (3) les conséquences de ce dépôt sur la physiologie de l'animal.

Droits : 2014 Ifremer
http://archimer.ifremer.fr/doc/00248/35909/34462.pdf
http://archimer.ifremer.fr/doc/00248/35909/

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Inorganic arsenic is a toxic environmental contaminant to which humans are mainly exposed through drinking water. This metalloid impairs functions of several key immune cells. Particularly, it reduces IL-2 secretion and proliferation of blood peripheral mononuclear cells stimulated by lectins that, however, do not mimic physiological T cell activation. The present study used isolated human T cells activated, in a more physiological manner, through stimulation with CD3/CD28 antibodies, to carefully analyze the impact of arsenic on T cell proliferation and cytokine expression. We demonstrate that non cytotoxic concentrations of sodium arsenite (As(III), 0.25-2μM) significantly reduce T cell proliferation by increasing the percentage of non dividing cells blocked in G1 phase and by preventing cyclin D3 and CDC25A expression. They also markedly, although not totally, reduces IL-2 expression at both mRNA and protein levels; however, metalloid-dependent inhibition of T cells could not be reversed by addition of recombinant IL-2. In addition, As(III) markedly reduces secretion of interferon-γ without impairing that of IL-4 and IL-13; it also decreases interferon-γ mRNA levels but increases those of IL-13. Finally, simultaneously to its immune effects, As(III) rapidly and potently increases expression of the redox-sensitive genes HMOX1, NQO1 and GCLM in activated T cells without altering the levels of reactive oxygen species. In conclusion, our results demonstrate that As(III) inhibits T cell proliferation, independently of IL-2, and alters the Th balance of cytokines secreted by co-stimulated T cells which thus constitute direct targets of this major environmental contaminant.
ISSN: 0300-483X

inserm-00872848
http://www.hal.inserm.fr/inserm-00872848
DOI : 10.1016/j.tox.2012.05.025
PUBMED : 22683347

Éditeur(s) : HAL CCSD
Résumé : To study the dynamics of an orogen-foreland system and more particularly the impact of surface processes on its development, we base our work on two main axes. In a first part, using analogue tapered wedge models, we investigate the interplay between tectonics, erosion and sedimentation during the orogenic growth. The basis model mimics the evolution of a wedge section extending from the orogen to its foreland basin, with both the structural and the lithological heritages simulated. In a second part, the focus is on the recent tectonic and geomorphologic processes affecting the Swiss Prealpes klippen belt and surrounding structural units (Molasse basin and Jura fold-and-thrust belt). Remote sensing analyses allow to evaluate the impact of tectonics on the drainage pattern and landscape morphology. In addition, local field investigations in the Prealpes provide information on the nature and kinematic of brittle fractures and the paleostress fields.
Afin d'étudier la dynamique d'un système orogène/avant-pays et plus particulièrement l'impact des processus de surface sur son développement, notre travail se base sur deux axes principaux. Dans une première partie, à l'aide de modèles analogiques de prisme d'accrétion, nous analysons les interactions entre la tectonique, l'érosion et la sédimentation au cours de la croissance de l'orogène. Le modèle de base reproduit l'évolution d'une section de prisme, qui s'étend de l'orogène au bassin d'avant-pays, et où les héritages à la fois structural et lithologique sont simulés. Dans une seconde partie, l'accent est mis sur la tectonique récente et les processus géomorphologiques qui affectent la klippe des Préalpes suisses et les unités structurales environnantes (le bassin molassique et le Jura). Des analyses de télédétection permettent d'évaluer l'influence de la tectonique sur le réseau de drainage et la morphologie du paysage. De plus, des analyses de terrain menées localement dans les Préalpes fournissent des informations sur la nature et la cinématique des fractures cassantes et des champs de paléocontraintes.
https://tel.archives-ouvertes.fr/tel-00138836

tel-00138836
https://tel.archives-ouvertes.fr/tel-00138836
https://tel.archives-ouvertes.fr/tel-00138836/document
https://tel.archives-ouvertes.fr/tel-00138836/file/These_Bonnet_2007.pdf

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The interseismic velocity field provided by geodetic methods is generally interpreted in the framework of a thick elastic lithosphere with a slipping fault at depth. Because lateral variations of lithospheric rheology play a key role in determining the geological strain distribution, I examine the idea that interseismic strain rate variations also occur in response to lateral variations in the elastic thickness of the lithosphere. Using a stress balance principle and some simplifying assumptions, I show using a 1D model that elastic thickness is inversely proportional to strain rate for the simple case of pure strike-slip faulting. Elastic thickness computed on three profiles crossing the San Andreas fault system (SAFS) suggests that the distribution of interseismic strain rate is compatible with a thick elastic lithosphere in the Great Basin-Sierra Nevada province and on the Pacific plate. Conversely, a thin plate with a shallow asthenosphere is needed on the SAFS to explain its high strain rate. A 2.5D Finite Element model of interseismic strain in the Carrizo Plain region in Central California shows how known vertical and horizontal variations of elastic properties refine 1D model predictions. In a case of a multiple fault system, I point out that the interseismic velocity is not causally tied to faults slip rate. Therefore, analysing the velocity field across the SAFS cannot reliably provide faults slip rate distribution as previously claimed. Rather, the apparent correlation between geologic slip rate and interseismic strain may only indicate that the elastic thickness plays a dominant role in controlling fault strength. Finally, I suggest that interseismic geodetic strain could be a new way to infer effective elastic plate thickness on the continents.
ISSN: 0012-821X

hal-00412155
https://hal.archives-ouvertes.fr/hal-00412155
DOI : 10.1016/j.epsl.2008.01.046

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The late Carboniferous accretionary system of the South Tianshan orogen (North-Western China) underwent complex structural and polymetamorphic evolution. Combined petrological, geochronological and microstructural analysis of (ultra)high-pressure (UHP) metabasites (eclogites and blueschists) enclosed in metapelites show a relict coarse-grained eclogitic fabric S2 surrounded by a dominant fine-grained eclogite and blueschist facies retrograde fabric S2. The S2 fabric is reworked by upright folds F3 that are responsible for a major shortening of the whole accretionary system. For both the eclogite and blueschist, peak and retrograde P–T conditions have been thermodynamically constrained at 25–26 kbar and 425–500 °C and 10–13 kbar and 500−550 °C respectively, suggesting a shared exhumation history. The garnet-whole rock-amphibole isochron in the blueschist yielded Lu–Hf and Sm–Nd ages of 326.0 ± 2.9 Ma and 318.4 ± 3.9 Ma respectively, interpreted to date the prograde to peak metamorphic assemblage. The retrograde path of the eclogite is characterized by heterogeneous omphacite recrystallization into a mylonitic fine-grained matrix and crystallization of blue amphibole. Microstructures in both pristine porphyroclastic and recrystallized fine-grained domains in the eclogite indicate a gradual evolution from constriction-dominated (L>S-type) to flattening-dominated (S>L-type) type of deformation, increase of fabric intensity reflected by gradually growing M-indexes and the development of lattice preferred orientation (LPO) typical for dislocation creep under slightly hydrated conditions. Recrystallization of the matrix in the blueschist is homogeneous, which indicates a matrix dominated channel flow during exhumation. These LPOs evolutions suggest a significant mechanical coupling with the upper plate concomitant with oroclinal bending of the Kazakh orocline. Lock up of Kazakh orocline is responsible for further stress increase resulting in horizontal shortening of South Tianshan accretionary wedge and development of D3 upright folding and steepening of the whole sequence.
ISSN: 1342-937X

hal-01481263
https://hal.archives-ouvertes.fr/hal-01481263
DOI : 10.1016/j.gr.2016.07.007

Éditeur(s) : HAL CCSD
Résumé : We present an experimental study of relations between hydraulic properties of clayey rocks and their deformation at bulk and micro scale. The experimentation is based on triaxial deformation of kaolinitic core samples, on permeability measurements, and on several methods of analysis of the microstructure. To produce the samples, remoulded kaolinite material is consolidated by axial loading up to 20 MPa in an oedometric cell. Then, in a triaxial cell, an undrained stress path is applied in order to induce shearing damage in the sample. The permeability of the sample is measured by fluid flow across the sample. Before and after these hydro-mechanical tests, the evolution and the homogeneity of the pore space and moreover the texture of the material are analysed by X-ray tomography, environmental scanning electron microscopy and thermic neutron diffraction. Contrary to expectations, the permeability at the sample scale does not vary significantly, although quite large deformation is reached. The final deformation is heterogeneous, with well-developed shear bands. It appears that the development of compacting and dilating zones generates a heterogeneous permeability field, which results in a negligible variation of the bulk permeability at the sample scale.
International Journal of Rock Mechanics and Mining Science

hal-00496407
https://hal.archives-ouvertes.fr/hal-00496407
DOI : 10.1016/j.ijrmms.2010.04.007

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
In the Arokam Tenere, the three studied massifs of granitoids are located around the N-S oriented Raghane mega-shear zone, which separates two of the main domains of the Tuareg shield, the Saharan metacraton and the Central Hoggar. The field observations, AMS analyses and U-Pb zircon dating were completed by a study of Landsat images because of the scarcity of outcrops in several parts of the studied area.;The image analysis allows to distinguish Arokam-East and Abdou granitoids in the eastern plutonic complex. It has also shown that the western plutonic complex corresponds to two different intrusions: the Yvonne granite and granodiorite. This is confirmed by the magnetic fabric that presents different characteristics in the different granitoids. U-Pb zircon dating and field observations show that the Arokam-West basement granite is much older (1915 Ma) than the Hanane granodiorite (582 Ma) in the central plutonic complex. Arokam-East and -West granites then belong to the Eburnean basement. The magnetic fabric of these granites is mainly associated with a post-magmatic deformation, probably of Pan-African age. Yvonne granodiorite is likely contemporaneous of the main displacement along the Raghane shear zone. The Yvonne granite (594 Ma) and Hanane granodiorite have a fabric similar to that previously obtained in most plutons of the Tiririne area. This fabric is related to the regional stress field, associated with the activity of the Raghane shear zone, during the late-magmatic phase in the plutons. On the contrary, the magnetic fabric of the Abdou pluton is still reflecting only the magma flow.
ISSN: 0899-5362

hal-00617478
https://hal.archives-ouvertes.fr/hal-00617478
DOI : 10.1016/j.jafrearsci.2011.02.007

Éditeur(s) : HAL CCSD AGU and the Geochemical Society
Résumé : International audience
We analyze focal mechanisms of shallow-intermediate earthquakes in a NW-SE transect along the western Betic Cordillera and Alboran Sea, and deep earthquakes located in the central Betics to constrain the state of stress at the Gibraltar Arc slow convergence area. Shallow earthquakes (< 40 km) are preferably clustered at the mountain front. A general NW-SE horizontal compression is compatible with the convergence, and NW plunging compression axes are in agreement with frontal thrust activity. Toward the Alboran Sea the earthquakes are progressively deeper, reaching intermediate depths (40-120 km) near the coast and supporting the present-day activity of subduction only in this area. The Iberian continental crust concentrates most of the intermediate seismicity and is forced to partially sink into the mantle, probably through the pull of the oceanic slab. This downdip pull together with the buoyancy of the Iberian continental crust produces the slab curvature, downdip extension in the external arc of the continental slab, and downdip compression in the inner arc. T axes highly dipping to the southeast at 90-120 km depth occur at the oceanic/continental transition. Deep earthquakes (> 620 km) show very similar focal mechanisms, fitting the general slab behavior of resistance to further descent at the 660 km discontinuity. Seismicity features evidence the present-day stress distribution in a context of transition from subduction to continental collision.
ISSN: 1525-2027

hal-00669889
https://hal.archives-ouvertes.fr/hal-00669889
DOI : 10.1029/2011GC003824

Éditeur(s) : Gauthier-Villars
Résumé : Analysis of Geosat sea level data over the period November 1986-November 1987 has evidenced long, low-frequency equatorial wave propagations over most of the equatorial Pacific basin (Delcroix et al.,1991). The succession of downwelling Kelvin, upwelling Kelvin, and upwelling Rossby waves has raised a series of questions. Is the observed upwelling Rossby wave due to a reflection process on the eastern boundary, or due to wind forcing near the equator? Why is there no evidence of a reflection of the downwelling Kelvin wave? Is this wave sequence a feature of the 1986-1987 El Nino phenomenon or is it to be found in the mean seasonal cycle? We used a linear model forced by the FSU wind stress to study these questions. The results, during the period November 1986-November 1987, show the successive downwelling/ upwelling Kelvin waves and upwelling Rossby wave as in the Geosat observations. Another test was made, using only the part of the forcing responsible for creating Kelvin waves, in order to evaluate the portion of the signals that was due to the reflection process and the part due to local forcing. It appears that wind forcing favourable to upwelling in the eastern part of the equatorial basin is the main mechanism which both generates the upwelling Rossby wave and inhibits the reflection of the downwelling Kelvin wave. However, the reflection of the upwelling Kelvin wave contributes to the upwelling Rossby wave signal, and makes it visible all the way from the eastern to the western sides of the equatorial Pacific. Results of a climatological run show that the successive downwelling/upwelling Kelvin and Rossby wave propagations are present in the mean seasonal cycle. However, the corresponding model signals, as well as the wind forcing anomalies, show a larger amplitude in 1986-1987.
Oceanologica Acta (0399-1784) (Gauthier-Villars), 1992 , Vol. 15 , N. 5 , P. 545-554

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/00101/21180/18797.pdf
http://archimer.ifremer.fr/doc/00101/21180/

Éditeur(s) : HAL CCSD American Institute of Physics
Résumé : International audience
Laser-induced periodic surface structures (LIPSS) were formed on Cu/Si or Cu/glass thin films using Nd:YAG laser beam (40 ps, 10Hz, and 30mJ/cm2). The study of ablation threshold is always achieved over melting when the variation of the number of pulses increases from 1 to 1000. But the incubation effect is leading to reduce the threshold of melting as increasing the number of laser pulse. Also, real time reflectivity signals exhibit typical behavior to stress the formation of a liquid phase during the laser-processing regime and helps to determine the threshold of soft ablation.Atomic Force Microscopy (AFM) analyses have shown the topology of the micro-crater containing regular spikes with different height. Transmission Electron Microscopy (TEM) allows finally to show three distinguished zones in the close region of isolated protrusions. The central zone is a typical crystallized area of few nanometers surrounded by a mixed poly-crystalline and amorphous area. Finally, in the region far from the protrusion zone, Cu film shows an amorphous structure. The real time reflectivity, AFM, and HR-TEM analyses evidence the formation of a liquid phaseduring the LIPSS formation in the picosecond regime. VC 2015 AIP Publishing LLC
ISSN: 0003-6951

hal-01226065
https://hal.archives-ouvertes.fr/hal-01226065
DOI : 10.1063/1.4935413

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
In this paper, we present the first estimate of the Holocene deformation along the southern front of Gibraltar arc (Morocco) and the first field constraints on the local 1755 CE Fes-Meknes surface rupturing earthquake which could be associated to the “Great Lisbon Earthquake” (M > 8.5) in November 1st, 1755. Using satellite imagery, aerial photographs and field investigations, we carried out a morphotectonic study along the ~ 150 km-long Southern Rif Front (SRF) to identify the most recent evidences of tectonic activity. Analyzed offset alluvial deposits confirm that (i) the last ~ 5 ka cumulative deformation leading to a slip rate of ~ 3.5 ± 1 mm/yr for this segment of the SRF is consistent with the GPS derived horizontal shortening rate of 2–4 mm/yr and (ii) a recent major earthquake ruptured a ~ 30 km-long segment along the SRF. Based on deposits dating and historical seismicity we propose that this seismic event occurred in 1755 as a local earthquake. Even though this 1755 local event cannot be considered as a strong aftershock of the main Lisbon seismic event (M > 8.5), their temporal closeness, their occurrence under the same convergent stress regime (~ NNW-SSE-oriented compression) and the fact that Fes-Meknes area was strongly shaken during the Lisbon earthquake, raises the question of the possible triggering of the Fes earthquake. Anyway, our new results suggest that most of the Nubia-Rif belt convergence is accommodated by the SRF, making it potentially the most destructive structure of the Rif.
ISSN: 0040-1951

hal-01622048
https://hal.archives-ouvertes.fr/hal-01622048
DOI : 10.1016/j.tecto.2017.05.036

Éditeur(s) : HAL CCSD Seismological Society of America
Résumé : International audience
The objective of this paper is to provide a better understanding of the relationship between the microseismicity, active tectonics, and crustal structures in the southwest Yukon Territory, Canada, in order to improve seismic‐hazard assessments in this region. We utilize data from a new dense seismic array that was deployed in the southwest Yukon in the summer of 2010. Data from the new seismic array significantly improve the magnitude completeness level in the region from ML 3.0 to 1.0. We analyze 980 events ranging in magnitudes from ML 0.2 to 4.7, at depths from 0 to 35 km. Relocation analysis using the progressive multiple event location shows that seismicity is concentrated in four main areas: (1) Yakutat block northern boundary-Fairweather fault, (2) Duke River fault, (3) southern Denali fault, and (4) a previously unrecognized northeast trending cluster that may highlight a previously unknown active fault. This cluster may contribute to stress and strain transfer inland from the Yakutat block region.
ISSN: 0037-1106

hal-00940935
https://hal.archives-ouvertes.fr/hal-00940935
DOI : 10.1785/0120130068

Éditeur(s) : HAL CCSD
Résumé : International audience
Millimeter waves (MMW) will be increasingly used for future wireless telecommunications. Previous studies on skin keratinocytes showed that MMW could impact the mRNA expression of Transient Receptor Potential cation channel subfamily Vanilloid, member 2 (TRPV2). Here, we investigated the effect of MMW exposure on this marker, as well as on other membrane receptors such as Transient Receptor Potential cation channel subfamily Vanilloid, member 1 (TRPV1) and purinergic receptor P2X, ligand-gated ion channel, 3 (P2 × 3). We exposed the Neuroscreen-1 cell line (a PC12 subclone), in order to evaluate if acute MMW exposures could impact expression of these membrane receptors at the protein level. Proteotoxic stress-related chaperone protein Heat Shock Protein 70 (HSP70) expression level was also assessed. We used an original high-content screening approach, based on fluorescence microscopy, to allow cell-by-cell analysis and to detect any cell sub-population responding to exposure. Immunocytochemistry was done after 24 h MMW exposure of cells at 60.4 GHz, with an incident power density of 10 mW/cm2. Our results showed no impact of MMW exposure on protein expressions of HSP70, TRPV1, TRPV2, and P2 × 3. Moreover, no specific cell sub-populations were found to express one of the studied markers at a different level, compared to the rest of the cell populations. However, a slight insignificant increase in HSP70 expression and an increase in protein expression variability within cell population were observed in exposed cells, but controls showed that this was related to thermal effect. Bioelectromagnetics. 37:444–454, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.
Bioelectromagnetics

hal-01371963
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01371963
DOI : 10.1002/bem.21995
PUBMED : 27483046

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Studies on tree biomechanical design usually focus on stem stiffness, resistance to breakage or uprooting, and elastic stability. Here we consider another biomechanical constraint related to the interaction between growth and gravity. Because stems are slender structures and are never perfectly symmetric, the increase in tree mass always causes bending movements. Given the current mechanical design of trees, integration of these movements over time would ultimately lead to a weeping habit unless some gravitropic correction occurs. This correction is achieved by asymmetric internal forces induced during the maturation of new wood. The long-term stability of a growing stem therefore depends on how the gravitropic correction that is generated by diameter growth balances the disturbance due to increasing self weight. General mechanical formulations based on beam theory are proposed to model these phenomena. The rates of disturbance and correction associated with a growth increment are deduced and expressed as a function of elementary traits of stem morphology, cross-section anatomy and wood properties. Evaluation of these traits using previously published data shows that the balance between the correction and the disturbance strongly depends on the efficiency of the gravitropic correction, which depends on the asymmetry of wood maturation strain, eccentric growth, and gradients in wood stiffness. By combining disturbance and correction rates, the gravitropic performance indicates the dynamics of stem bending during growth. It depends on stem biomechanical traits and dimensions. By analyzing dimensional effects, we show that the necessity for gravitropic correction might constrain stem allometric growth in the long-term. This constraint is compared to the requirement for elastic stability, showing that gravitropic performance limits the increase in height of tilted stem and branches. The performance of this function may thus limit the slenderness and lean of stems, and therefore the ability of the tree to capture light in a heterogeneous environment.
ISSN: 0022-5193

hal-00534316
https://hal.archives-ouvertes.fr/hal-00534316
DOI : 10.1016/j.jtbi.2008.10.011

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
This paper focuses on the analyses of the clastic sedimentary infill of the Coastal Plain of Eastern Mexico, which initiated synchronously with the Laramide orogeny in the vicinity of the Golden Lane. Results of these analyses are used as boundary conditions for calibrating/interpreting seismic profiles across more distal depocenters in the offshore of the Gulf of Mexico, from the sea shore and continental slope in the west to the abyssal plain in the east. The objective of the study is to better predict the reservoir distribution in the Deep offshore Basin of the Gulf of Mexico (DBGM), in order to explore for petroleum. The Coastal Plain is underlain by three morpho-tectonic domains: the tectonic front of the Sierra Madre Orientale (SMO), the Chicontepec deep water flexural basin, and the Tuxpan Platform (also known as the Golden Lane). Each domain is characterized by a distinct, dominantly siliciclastic Cenozoic lithostratigraphy. After a Jurassic rifting episode, followed by thermal subsidence, the oceanic basin and its western passive margin were deformed during the Upper Cretaceous and Paleogene, by far field stresses associated with the Cordilleran-Laramide Orogeny. Starting in the Late Cretaceous-Early Paleogene and during the Early Eocene, the tectonic load associated with the Laramide Orogen (Sierra Madre Oriental, SMO) caused flexural subsidence of the foreland located under the Coastal Plain. During this period, a massive transfer of siliciclastic sediments occurred from the Laramide foothills into the adjacent foreland. Sediments were eroded of the Sierra Madre tectonic wedge. Loading by these sediments pushed source units associated with the former passive margin down ward. The first syn-tectonic sediments of the Laramide orogeny were turbiditic silt layers in submarine fans which record also numerous collapse episodes and gravity slides. During the Late Eocene and Oligocene, the flexural subsidence stopped in the hinterland, whereas the subsidence of the passive margin resumed. This resulted in a change in the overall sedimentary architecture of the basin. Paleo-highs and reefs facies of the Golden Lane were flooded. Clastics by-passed the reefs and progradational clastic stratification formed as sediment moved towards the DBGM in the east. The final depositional environment of the continental platform/Coastal Plain became deltaic, marked by a succession of sand bars, levees and channels systems. From Miocene times onward, a system of gravitational listric faults developed near the platform to slope transition, resulting in a coeval compressional system at the transition between the slope and the abyssal plain. This system is driven by sediments charge. Because the sedimentation rate is larger than the subsidence, a large amount of clastics and slumped sediments are deposited in hangingwall basins.
ISSN: 0264-8172

hal-00424586
https://hal.archives-ouvertes.fr/hal-00424586
DOI : 10.1016/j.marpetgeo.2008.03.009

Éditeur(s) : HAL CCSD Cambridge University Press (CUP)
Résumé : International audience
Background. Adverse psychosocial working environments characterized by job strain (the combination of high demands and low control at work) are associated with an increased risk of depressive symptoms among employees, but evidence on clinically diagnosed depression is scarce. We examined job strain as a risk factor for clinical depression. Method. We identified published cohort studies from a systematic literature search in PubMed and PsycNET and obtained 14 cohort studies with unpublished individual-level data from the Individual-Participant-Data Meta-analysis in Working Populations (IPD-Work) Consortium. Summary estimates of the association were obtained using random-effects models. Individual-level data analyses were based on a pre-published study protocol. Results. We included six published studies with a total of 27 461 individuals and 914 incident cases of clinical depression. From unpublished datasets we included 120 221 individuals and 982 first episodes of hospital-treated clinical depression. Job strain was associated with an increased risk of clinical depression in both published [relative risk (RR) = 1.77, 95% confidence interval (CI) 1.47-2.13] and unpublished datasets (RR = 1.27, 95% CI 1.04-1.55). Further individual participant analyses showed a similar association across sociodemographic subgroups and after excluding individuals with baseline somatic disease. The association was unchanged when excluding individuals with baseline depressive symptoms (RR = 1.25, 95% CI 0.94-1.65), but attenuated on adjustment for a continuous depressive symptoms score (RR = 1.03, 95% CI 0.81-1.32). Conclusions. Job strain may precipitate clinical depression among employees. Future intervention studies should test whether job strain is a modifiable risk factor for depression.
ISSN: 0033-2917

hal-01560152
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01560152
DOI : 10.1017/S003329171600355X
PUBMED : 28122650

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
Radiofrequency radiations constitute a new form of environmental pollution. Among them, millimeter waves (MMW) will be widely used in the near future for high speed communication systems. This study aimed therefore to evaluate the biocompatibility of MMW at 60 GHz. For this purpose, we used a whole gene expression approach to assess the effect of acute 60 GHz exposure on primary cultures of human keratinocytes. Controls were performed to dissociate the electromagnetic from the thermal effect of MMW. Microarray data were validated by RT-PCR, in order to ensure the reproducibility of the results. MMW exposure at 20 mW/cm2, corresponding to the maximum incident power density authorized for public use (local exposure averaged over 1 cm2), led to an increase of temperature and to a strong modification of keratinocyte gene expression (665 genes differentially expressed). Nevertheless, when temperature is artificially maintained constant, no modification in gene expression was observed after MMW exposure. However, a heat shock control did not mimic exactly the MMW effect, suggesting a slight but specific electromagnetic effect under hyperthermia conditions (34 genes differentially expressed). By RT-PCR, we analyzed the time course of the transcriptomic response and 7 genes have been validated as differentially expressed: ADAMTS6, NOG, IL7R, FADD, JUNB, SNAI2 and HIST1H1A. Our data evidenced a specific electromagnetic effect of MMW, which is associated to the cellular response to hyperthermia. This study raises the question of co-exposures associating radiofrequencies and other environmental sources of cellular stress.
ISSN: 1932-6203

hal-01118066
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01118066
PUBMED : 25302706
DOI : 10.1371/journal.pone.0109435
PUBMEDCENTRAL : PMC4193780

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
In this study, we quantify and analyze the spatial and temporal evolution of the surface displacement of Kahrod landslide located in the center of Alborz range (Iran) within the Haraz valley. This landslide represents a threat for this main drainage axis and its numerous infrastructures. We present three sets of displacement vectors based on GPS technique. An 8-benchmark network has been surveyed four times on a 1-year period basis. It provides accurate information on the rate of displacement within the landslide, and addresses the problem of the mechanical resistance of a small hillock, down slope, under the stress imposed by the landslide. Then. this network is densified (57 marks) and measured twice in 6 months using a rapidstatic approach. This yields to a dense description of surface deformation over the whole landslide. Finally, a 1-year time series of permanent GPS recordings is presented and compared to rainfall. Furthermore, we analyze Envisat radar differential interferograms (DInSAR) spanning the same period as permanent GPS. These geodetic data allow to precisely determine the limits of the current sliding zone and to describe the spatial and temporal evolution of surface displacement. The combination of geodesy and field observations leads to a precise description of the past and present kinematics behavior of Kahrod landslide. The chaotic nature of the sliding mass suggests a first catastrophic landslide in a first episode. During the period of observation, the landslide appears to deform quite steadily, and the evidence of short-term correlation between rainfall and deformation amplitude needs to be confirmed by future measurements. Carrying on the acquisition of GPS and InSAR data within the sliding mass but also within adjacent bedrock should give fundamental information with regards to major activation processes (river sapping, water seeping, earthquakes, or failure within the frontal hill of bedrock) and their potential consequences.
ISSN: 1435-9529

hal-00411318
https://hal.archives-ouvertes.fr/hal-00411318
DOI : 10.1016/j.enggeo.2008.02.013

Éditeur(s) : HAL CCSD AGU and the Geochemical Society
Résumé : International audience
[1] Statistical analysis of modern oceanic subduction zone parameters, such as the age of a downgoing plate or the absolute plate motions, is performed in order to investigate which parameter controls the dip of a slab and, conversely, what the influence of slab geometry is on upper plate behavior. For that purpose, parameters have been determined from global databases along 159 transects from all subduction zones that are not perturbed by nearby collision or ridge/plateau/seamount subduction. On the basis of tomographic images, slabs that penetrate through, or lie on, the 670 km discontinuity are also identified. The results of the statistical analysis are as follows: (1) Back-arc stress correlates with slab dip, i.e., back-arc spreading is observed for deep dips (deeper than 125 km) larger than 50°, whereas back-arc shortening occurs only for deep dips less than 30°. (2) Slab dip correlates with absolute motion of the overriding plate. The correlation is even better when the slab lies on, or even more penetrates through, the 670 km discontinuity. (3) Slabs dip more steeply, by about 20° on average, beneath oceanic overriding plates than beneath continental ones. (4) Slabs dip more steeply on average by about 10° near edges. (5) Slab dip does not correlate with the magnitude of slab pull, the age of subducting lithosphere at the trench, the thermal regime of the subducting lithosphere, the convergence rate, or the subduction polarity (east versus west). The present study provides evidence that the upper plate absolute motion plays an important role on slab dip, as well as on upper plate strain. Retreating overriding plates are often oceanic ones and thus may partially explain the steeper slab dips beneath oceanic upper plates. One can infer that low slab dips correlate well with compression in continental advancing upper plates, whereas steep dips are often associated with extension in oceanic retreating upper plates. Excess weight of old slabs is often counterbalanced by other forces, probably asthenospheric in origin, such as lateral mantle flow near slab edges or anchor forces, to determine slab dip. Components: 12,676 words, 13 figures, 1 table.
ISSN: 1525-2027

hal-01261567
https://hal.archives-ouvertes.fr/hal-01261567
https://hal.archives-ouvertes.fr/hal-01261567/document
https://hal.archives-ouvertes.fr/hal-01261567/file/lallemandG32005.pdf
DOI : 10.1029/2005GC000917

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Diploid budding yeast undergoes rapid mitosis when it ferments glucose, and in the presence of a non-fermentable carbon source and the absence of a nitrogen source it triggers sporulation. Rich medium with acetate is a commonly used pre-sporulation medium, but our understanding of the molecular events underlying the acetate-driven transition from mitosis to meiosis is still incomplete. We identified 263 proteins for which mRNA and protein synthesis are linked or uncoupled in fermenting and respiring cells. Using motif predictions, interaction data and RNA profiling we find among them 28 likely targets for Ume6, a subunit of the conserved Rpd3/Sin3 histone deacetylase-complex regulating genes involved in metabolism, stress response and meiosis. Finally, we identify 14 genes for which both RNA and proteins are detected exclusively in respiring cells but not in fermenting cells in our sample set, including CSM4, SPR1, SPS4 and RIM4, which were thought to be meiosis-specific. Our work reveals intertwined transcriptional and post-transcriptional control mechanisms acting when a MATa/α strain responds to nutritional signals, and provides molecular clues how the carbon source primes yeast cells for entering meiosis. Our integrated genomics study provides insight into the interplay between the transcriptome and the proteome in diploid yeast cells undergoing vegetative growth in the presence of glucose (fermentation) or acetate (respiration). Furthermore, it reveals novel target genes involved in these processes for Ume6, the DNA binding subunit of the conserved histone deacetylase Rpd3 and the co-repressor Sin3. We have combined data from an RNA profiling experiment using tiling arrays that cover the entire yeast genome, and a large-scale protein detection analysis based on mass spectrometry in diploid MATa/α cells. This distinguishes our study from most others in the field-which investigate haploid yeast strains-because only diploid cells can undergo meiotic development in the simultaneous absence of a non-fermentable carbon source and nitrogen. Indeed, we report molecular clues how respiration of acetate might prime diploid cells for efficient spore formation, a phenomenon that is well known but poorly understood.
ISSN: 1874-3919

hal-01122122
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01122122
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01122122/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01122122/file/Integrated%20RNA-%20and%20protein%20profiling%20of%20fermentation.pdf
DOI : 10.1016/j.jprot.2015.01.015