Éditeur(s) : Elsevier
Résumé : Overexploitation of marine resources remains a problem worldwide. Many works advocate for the use of marine reserves as a central element of future stock management in a sustainable perspective. In the present paper, we address the influence of protected areas upon fisheries sustainability within an eco-systemic framework through a dynamic bio-economic model integrating a trophic web, catches and environmental uncertainties. The model is spatially implicit. The evaluation of the ecosystem is designed through the respect along time of constraints of both conservation and guaranteed captures. Using the mathematical concept of invariance kernel in a stochastic context, we define different MPA effects according to biodiversity catches or mixed points of view. Numerical simulations inspired from data of Abore coral reef reserve in New Caledonia illustrate the main concepts. In this case, it is pointed out how MPA conservation effect is not necessarily conflicting with MPA catches effect. it is shown that such a co-viability requires medium exploitation rate. Moreover, the climatic changes represented by rise in cyclonic events seem to reinforce these assertions. (C) 2007 Elsevier B.V. All rights reserved.
Ecological Modelling (0304-3800) (Elsevier), 2007-11 , Vol. 208 , N. 2-4 , P. 353-366

Droits : 2007 Elsevier B.V. All rights reserved.
http://archimer.ifremer.fr/doc/2007/publication-3510.pdf
DOI:10.1016/j.ecolmodel.2007.06.018
http://archimer.ifremer.fr/doc/00000/3510/

Éditeur(s) : HAL CCSD
Résumé : International audience
Treatment failure and symptomatic relapse are major concerns in American tegumentary leishmaniasis (ATL). Such complications are seen frequently in L.guyanensis infections where patients respond variously to first-line anti-leishmanials and are more prone to develop chronic cutaneous leishmaniasis. The factors underlying this pathology, however, are unknown. Recently ,: we reported that a dsRNA virus (LRV1) nested within L.guyanensis parasites is able to exacerbate experimental murine leishmaniasis by inducing a hyper-inflammatory response. This report investigates the prevalence of LRV1 in human L.guyanensis infection and its effect on treatment efficacy as well as its correlation to symptomatic relapses after the first-line treatment. In our cohort of 75 patients diagnosed with primary-localised ATL, the prevalence of LRV1+ infection was elevated to 58%. All patients infected with LRV1-negative L.guyanensis were cured after one (22/31 i.e.71%) or two (31/31 i.e.100%) doses of pentamidine. Oppositely, 12 out of the 44 LRV1-positive patients presented with persistent infection and symptomatic relapse required extended therapy and the use of second-line drugs. Finally, LRV1 presence was associated with a significant increase in intra-lesional inflammatory markers. In conclusion, LRV1 status in L.guyanensis infection is significantly predictive (p=0.0009) of first-line treatment failure and symptomatic relapse, and could stand to guide therapeutic choices in ATL
Journal of Infectious Diseases

hal-01175528
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01175528
DOI : 10.1093/infdis/jiv355
PUBMED : 26123564

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Yearly monitoring in one of the most affected coastal zones by the Prestige oil spill, namely Nemiña and O Rostro beaches (NW Spain), has been carried out since 2004. Topographic data of beaches revealed seasonal altimetric changes up to 4 m that would prevent the on shore persistence of oil. However, surficial and subsurficial oil was detected in the intertidal area of both beaches in all campaigns. The hydrocarbon analysis confirmed that this oil corresponded to the Prestige oil, even nine years after the accident. Tar balls were highly biodegraded suggesting that the oil was accumulated on the subtidal sediments for a long time and transported to the coast by the action of waves. The present work provides new evidence of the long term persistence of deep oil spills from wrecks in marine areas where the hydrodynamic conditions play a twofold key role, in determining the exposed coastal area to recurrent contamination and in burying and resurfacing the oil in the intertidal zone.
ISSN: 0304-3894

hal-01071707
https://hal.archives-ouvertes.fr/hal-01071707
DOI : 10.1016/j.jhazmat.2013.01.057

Résumé : Spiny lobsters are an important component of the coastal fisheries around the Martinique island. This study aimed to assess the contamination by kepone of the two main species Panulirus argus and P. guttatus in the main fishery area laying along the eastern coast of Martinique. The objectives of the study were to describe the distribution of the spiny lobster contamination in the area, to explore possible relationships with some biological parameters such as individual size, sex and colour of tegument, as well as characterize difference of kepone concentration between the muscle and soft flesh of the head, in view of helping the definition of further fishery management measures. The analyses were done from chemical analyses of 125 samples of spiny lobsters gathered from 2008 to 2010 all around the island, and from a specific set of 200 new observations from a specific survey carried out in 2011 in the study area. For both species, the results show a diffusion of the contamination all over the coral shoals, close to contaminated catchment basins, with a strong decrease just outside these areas. For the Caribbean spiny lobster, a strong relationship between kepone concentration and individual size was identified, and less for the Spotted spiny lobster. For the two species, the concentration of kepone found in soft flesh of the head was more than twice as in the muscle. Finally, the difference of contamination between the two species appeared strongly linked with their biology.
La langouste blanche Panulirus argus et la langouste brésilienne P. guttatus représentent environ 25 % du chiffre d’affaires des pêcheurs professionnels de Martinique. Une part très importante des captures de ces espèces proviennent du platier continental de la zone centre-atlantique de l’île. L’étude réalisée en 2011 visait à approfondir les connaissances sur la distribution de la contamination par la chlordécone des langoustes dans la zone centre- atlantique de la Martinique, d’explorer d’éventuelles relations entre cette contamination et des paramètres biologiques des individus comme la taille, le sexe et leur pigmentation tégumentaire, et d’analyser la différence de contamination entre la queue et les chairs molles du céphalothorax, en vue d’aider à la définition de mesures de réglementation de la pêche dans ce secteur. L’étude s’appuie sur un ensemble de 125 échantillons rassemblés de 2008 à 2010 pour les deux espèces autour de la Martinique, complétés par 200 échantillons constitués pour la présente étude dans la zone centre-atlantique en 2011. Le rapport est précédé d’un rappel d’éléments sur la biologie et sur l’état de la pêche des langoustes en Martinique. Pour les deux espèces, l’étude met en évidence une extension de la contamination à l’ensemble du platier corallien au pied des bassins versants contaminés, puis une nette diminution au-delà. Pour la langouste blanche, cette contamination est en relation avec la taille des individus, en liaison avec leur plongée progressive vers le large. Cette relation avec la taille est moins marquée pour la langouste brésilienne, espèce beaucoup plus inféodée aux eaux littorales. Pour les deux espèces, les chairs molles du céphalothorax apparaissent plus de deux fois plus contaminées que le muscle caudal. Les différences de contamination observées entre langouste blanche et la langouste brésilienne sont cohérentes avec les connaissances sur la biologie de chaque espèce.

Droits : Délégation Antilles
http://archimer.ifremer.fr/doc/00088/19971/17638.pdf
http://archimer.ifremer.fr/doc/00088/19971/

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : L’exploitation commerciale des produits forestiers non ligneux a animé et anime encore au plan international les débats sur la gestion durable des forêts, notamment par son apport en matière de conservation, d’amélioration des conditions d’existence des populations locales et de gestion participative. Cependant, l’exploitation commerciale des PFNL soulève la problématique de la durabilité tant au plan écologique, économique que sociopolitique. La présente recherche traite de cette problématique en prenant comme PFNL d’illustration le raphia dans la forêt marécageuse Hlanzoun. Elle vise à analyser la durabilité socio-économique et environnementale de l’exploitation du raphia dans la forêt marécageuse « Hlanzoun ». La méthodologie utilisée est une combinaison d’approches quantitatives et qualitatives. Les outils d’analyse de données utilisés sont entre autre, la statistique descriptive, l’analyse filière des revenus d’exploitation et des valeurs ajoutées et l’analyse du système socio-écologique. Nos résultats montrent que le raphia est une plante à usages multiples. Que ce soit les feuilles, les fibres, la sève ou le tronc, tout ou presque peut être valorisé sur le raphia. Au niveau des villages riverains du Hlanzoun l’exploitation de la sève du raphia et sa transformation en alcool alimentaire est de loin le type d’usage qui procure le plus de revenu malgré le fait que les autres types d’usages mobilisent un nombre plus important d’acteurs. L’exploitation commerciale de ce PFNL se déploie suivant une organisation relativement simple et avec des caractéristiques propres à la plupart des activités de la petite production marchande des économies sous-développées en crise. Cette exploitation est essentiellement articulée autour des coupeurs/collecteurs, des intermédiaires commerciaux, des agents de transformation/conditionnement et des consommateurs des produits finis. La contribution annuelle totale de la filière raphia au développement a été estimée à 192 429 633 Fr. CFA (environ 385 000 dollar) et les revenus d’exploitation de tous les acteurs ont un signe positif malgré le faible niveau de technologie et de formation. Le raphia apporte donc des revenus relativement importants aux divers acteurs en dépit des handicaps de la filière et du déficit d’équité dans la répartition des richesses produites. Au plan de la gouvernance, on note un déficit d’instances, de règles et de procédures, dont l’effectivité et la légitimité sont clairement établies. Cet état de chose laisse le parc à raphia dans un régime d’accès « libre » mais seulement pour les riverains ; nous nous retrouvons donc en présence d’un système de cueillette, caractérisé par l’exploitation de plants immatures et la surexploitation, mettant en péril la capacité de renouvellement de la ressource et même l’avenir de la filière. On note cependant un effort de contrôle de l’accès des non riverains et des tentatives d’adaptation des riverains. En effet, le nombre d’exploitants est passé de 148 à 92 entre 2008 et 2010 et le nombre de pieds de raphia saignés est passé de 15 452 à 8 832 durant la même période. Au total, l’exploitation du raphia dans le Hlanzoun s’inscrit dans un environnement défavorable par rapport aux exigences de développement durable d’une filière de PFNL. Mais les divers acteurs sont à présent conscients de la nécessité d’agir pour une meilleure réglementation de l’accès et de l’exploitation.
The commercial use of non woody forest products is a crucial issue in the international debate on the sustainable management of forests. These products are supposed to contribute to conservation by improving local populations’ livelihood and their involvement in forest management. This study lies within the scope of two South-South Cooperation projects (PSC 22P07 and PSC 03T08) implemented by the CEBEDES NGO with the financial support of the Kingdom of the Netherlands. It aims at analyzing the socioeconomic and environmental sustainability of the raffia stands management in the swamp forest "Hlanzoun ". This small forest is located in one of Benin southern Wetlands in the municipality of Zogbodomey.The methodology to assess raffia socioeconomic performances relies on the estimation of the values added within the raffia value chains. Stakeholders at every segment of the value chains have been surveyed on the incomes obtained out of raffia. The methodology to assess the sustainability of the management relies on a simple indicator measuring the ratio of younger to elder palms. Palms in stands have been counted according to their age group. The survey confirms that raffia is a multi-purpose plant used for its leaves, fibers, sap and trunk. In villages at the borders of the Hlanzoun forest, harvesting the raffia sap on standing palms and processing it into alcohol are a major income generating activity. Alcohol is then marketed through a network of collectors, wholesalers and petty traders up to the consumers. The contribution of raffia to local and regional development was estimated by the total incomes generated at 192.429.633 F CFA. All stakeholders earn positive and significant incomes in spite of the low level of technology and skills, but traders receive a large share of the wealth produced. As regard to governance, "free" access only concerns residents and efforts are made to control the access of non-residents. One notes a deficit of legitimated authorities, rules and procedures for a sustainable use: Restrictions on the harvest of immature palms are not anymore enforced and it endangers the renewal capacity of the resource. But at the same time, the number of operators seems to be decreasing (from 148 to 92 between 2008 and 2010, whereas the number of harvested raffia palms decreased from 15,452 to 8,832 during the same period). A self-regulation might occur, due to the fact that a livelihood of local people relies on a diversity of income generating activities. In total, the operation of Raffia in Hlazoun is in an unfavorable environment with the requirements of sustainable development in a sector of NTFF. But the various actors are now aware of the need for action to better regulate access and operation.
Bénin

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.5556
http://journals.openedition.org/etudescaribeennes/5556

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
Background: Color polymorphism in the nacre of pteriomorphian bivalves is of great interest for the pearl culture industry. The nacreous layer of the Polynesian black-lipped pearl oyster Pinctada margaritifera exhibits a large array of color variation among individuals including reflections of blue, green, yellow and pink in all possible gradients. Although the heritability of nacre color variation patterns has been demonstrated by experimental crossing, little isknown about the genes involved in these patterns. In this study, we identify a set of genes differentially expressed among extreme color phenotypes of P. margaritifera using a suppressive and subtractive hybridization (SSH) method comparing black phenotypes with full and half albino individuals.Results: Out of the 358 and 346 expressed sequence tags (ESTs) obtained by conducting two SSH libraries respectively, the expression patterns of 37 genes were tested with a real-time quantitative PCR (RT-qPCR) approach by pooling five individuals of each phenotype. The expression of 11 genes was subsequently estimated for each individual in order to detect inter-individual variation. Our results suggest that the color of the nacre is partiallyunder the influence of genes involved in the biomineralization of the calcitic layer. A few genes involved in the formation of the aragonite tablets of the nacre layer and in the biosynthesis chain of melanin also showed differential expression patterns. Finally, high variability in gene expression levels were observed within the black phenotypes.Conclusions: Our results revealed that three main genetic processes were involved in color polymorphisms: the biomineralization of the nacreous and calcitic layers and the synthesis of pigments such as melanin, suggesting that color polymorphism takes place at different levels in the shell structure. The high variability of gene expression found within black phenotypes suggests that the present work should serve as a basis for future studies exploringmore thoroughly the expression patterns of candidate genes within black phenotypes with different dominant iridescent colors.
ISSN: 1471-2164

hal-01260141
https://hal.archives-ouvertes.fr/hal-01260141
https://hal.archives-ouvertes.fr/hal-01260141/document
https://hal.archives-ouvertes.fr/hal-01260141/file/Lemer-2015-BMCGenom-Identification.pdf
DOI : 10.1186/s12864-015-1776-x

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : La cinematografía contemporánea es uno de los vehículos de difusión privilegiados en las sociedades de consumo actuales. Se considera relevante reconocer la manera en que esta construye sus mensajes y se posiciona en el imaginario social. Los filmes The Bling Ring (2013) de la norteamericana Sofia Coppola, Les derniers jours du monde (2009) de los hermanos franceses Arnaud y Jean-Marie Larrieu y The Great Gatsby (2013) del australiano Baz Luhrmann, tienen como punto en común la incursión en un mundo de lujos y ostentación. El análisis privilegia determinados pasajes textuales, los cuales permiten identificar los elementos constitutivos, las estrategias visuales y los valores sociales que los tres productos cinematográficos emplean en la representación del campo de la sobreabundancia. A pesar de la diversidad de contextos socioculturales, el objetivo es el de reconocer las afinidades textuales al exponer estos ámbitos exclusivos y señalar qué preocupaciones simbólicas y sociales manifiestan.
In current consumer societies, cinematography plays a privileged role as a spreading vehicle. So, it is relevant to recognize how films build their messages and fix in the social imaginary. The The Bling Ring film (2013), by American Sofia Coppola; Les Derniers Jours du monde (2009), by French brothers Arnaud and Jean -Marie Larrieu; and The Great Gatsby (2013), by Australian Baz Luhrmann, have in common the exploration of a luxurious and ostentatious world. The analysis focusses on certain text passages, allowing the identification of constituent elements, visual strategies and social values used by these three films in the representation of the overabundance field. Despite the diversity of cultural contexts, the goal is to recognize textual affinities on exposing these exclusive spaces, and to point out the expressed symbolic and social concerns.
La cinématographie contemporaine est l'un des modes privilégiés de diffusion dans les sociétés de consommation actuelles. Il est essentiel de connaître la manière dont se construisent ses messages et comment ils se positionnent dans l’imaginaire social. Les films The Bling Ring (2013), de l´Américaine Sofia Coppola, Les derniers jours du monde (2009) des frères français Arnaud y Jean-Marie Larrieu et The Great Gatsby (2013) de l'Australien Baz Luhrmann, ont pour point commun l'incursion dans le monde du luxe et de l’ostentation. L'analyse privilégie des passages textuels déterminés qui permettent d'identifier les éléments constitutifs, les stratégies visuelles et les valeurs sociales que les trois textes cinématographiques emploient dans la construction de la représentation de la surabondance. Après avoir exposé leurs domaines exclusifs et souligné leurs préoccupations symboliques et sociales, l’objectif est d’identifier leurs affinités textuelles à travers la diversité de contextes socioculturels présentés.

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.7331
http://journals.openedition.org/etudescaribeennes/7331

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Tourism economic development and traditional culture preservation has been a topic of concern and discussion in academic fields. Based on the development of the tourism economy in Xijiang Miao Village of China, the paper focuses on the analysis of the preservation methods and effects of traditional culture in Chinese ethnic communities. Finally, it points out that the preservation of traditional cultures and tourism development in ethnic communities are not always contradictory. Including the community’s participation can help achieve a “win-win” situation for all actors.
Le développement économique du tourisme et la préservation de la culture traditionnelle est un sujet de préoccupation et de discussion dans les milieux universitaires. Basé sur le développement de l'économie du tourisme du village Miao Xijiang en Chine, cet article se concentre sur l'analyse des méthodes de préservation et leurs conséquences sur la culture traditionnelle des communautés ethniques chinoises. Enfin, l’étude souligne que la préservation des cultures traditionnelles et le développement du tourisme dans les communautés ethniques ne sont pas toujours contradictoires ; la participation de la communauté peut aider à atteindre une situation "gagnant-gagnant" pour tous les acteurs.
Chine
Guizhou
Leisha

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.7556
http://journals.openedition.org/etudescaribeennes/7556

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The base of the Faro contouritic drift (IODP Site U1386) on the northern margin of the Gulf of Cádiz (Algarve margin) is characterized by two sequences of frequent gravity deposits with different ages and compositions. Among these gravity deposits, several relatively thick debrites (up to 12 m) have been observed and studied in detail.Sedimentological analyses have been performed and because of non-turbulent behavior of debris flows, detailed micropaleontological studies could be realized. Planktonic foraminifera thus allowed establishing a detailed biostratigraphy of these deposits. Benthic foraminifer and ostracod assemblages were used to evaluate the origin of the sediment composing these debris flows and estimate their run-out distance.These debrites are dated from Early Pliocene and early Pleistocene, and were deposited in a mesobathyal environment. They comprise silty mud clasts and matrixes with sand content up to 34%. The Early Pliocene debrites are bioclast-rich whereas the Early Pleistocene debrite is enriched in terrigenous particles. The data indicates that these debrites were triggered on the continental shelf and traveled less than 100 km, eroding the seafloor all along their path for the Early Pliocene debrites and only the first part of their path for the early Pleistocene debrite. Matrixes originate from failure areas whereas eroded sediments along the flow pathway are incorporated into the flow as clasts.High abundance of shelf fauna during the Early Pliocene and great supply of terrigenous particles from rivers during the early Pleistocene in the south-western Iberian margin have favored gravity flows from the continental shelf to the slope. The contouritic paleo-moat of the Faro drift has been a determining channeling feature for gravity flows along the Algarve margin during the early Pleistocene, testifying of the strong interaction between MOW circulation and down-slope processes. Tectonic and diapiric activities were significant during Early Pliocene and early Pleistocene on the Algarve margin and could have been triggering parameters of failures related to these debris flows.
ISSN: 0025-3227

hal-01356172
https://hal.archives-ouvertes.fr/hal-01356172
DOI : 10.1016/j.margeo.2015.08.018

Éditeur(s) : Elsevier
Résumé : Choice of sampling method and survey period can have an important impact on the perception of the structure and dynamics of an ecological community. For the Celtic Sea fish assemblage we compared data obtained by three different trawl surveys: an autumn groundfish survey with a GOV trawl, and a spring and an autumn groundfish survey, both carried out with a Portuguese high-headline trawl. Time-series of abundance estimates were not consistent among surveys for all species and were generally very noisy. An analysis of variance components showed that the sampling method contributed more to the variance in abundance estimates compared to survey period, interannual variability, or even sampling variance. Overall community assessments based on indicators such as proportions of non-commercial and piscivorous species, and the proportion of benthic species showed similar trends for all data series. The shape of the size spectrum based on abundances per length class summed over all fish species, although stable over time, was highly sensitive to the sampling method. With the exception of size spectra, community indicators for marine fish assemblages monitored by surveys seem to be robust to survey period and trawling gear, but species abundance trends are method dependent.
ICES Journal of Marine Science (1054-3139) (Elsevier), 2004-05 , Vol. 61 , N. 3 , P. 351-362

Droits : 2004 International Council for the Exploration of the Sea. Published by Elsevier Science Ltd
http://archimer.ifremer.fr/doc/2004/publication-899.pdf
DOI:10.1016/j.icesjms.2004.01.004
http://archimer.ifremer.fr/doc/00000/899/

Éditeur(s) : HAL CCSD
Résumé : The territory of Armenia was located in the collision zone between Arabia and Eurasia, and is the seat of active intercontinental deformations, which was attested by the many historical earthquakes that have occurred in this region. All these destructive earthquakes show a strong regional seismic activity, and therefore it is important to evaluate the seismic hazard associated with active structures that generates this seismicity.This study presents the results of the analysis of the active tectonics within the northwestern and southeastern extensions of the Pambak-Sevan-Syunik fault (PSSF), a major right-lateral strike-slip fault cutting through Armenia (NW - SE). Quantifying the deformations in terms of geometry, kinematics, slip rates and earthquake activity, using cosmogenic 3He, OSL/IRSL and radiocarbon dating techniques, reveal different behaviors between the two regions.Within the northwestern extension, in the region of Amassia, the PSSF bends to the west and splits into two main WNW-ESE trending reverse faults defining a compressional pop-up structure. We estimate an uplift rate and a shortening rate of 0.5 ± 0.1 mm/y and 1.4 ± 0.6 mm/y, respectively. This suggests that most of the ~2 mm/y right lateral movement of the PSSF seems to be absorbed within the Amasia pop-structure.Within the southeastern extension, in the region of Tsghuk volcano, the PSSF shows signs of dying out at the southernmost tip of the Syunik graben. A very slow NS trending normal faulting associated with a slight right-lateral movement characterizes the tectonic activity in the region of Tsghuk volcano. We estimate vertical slip rates, EW stretching rate, and right-lateral slip rate of ~0.2 mm/y, ~0.1 mm/y and ~0.05 mm/y, respectively. These results lead to the conclusion that the right lateral movement observed further north along the PSSF is mainly transferred within other active faults further west within the Karabagh (Hagari fault or other structures further northwestwards).
L’Arménie se situe dans la zone de collision entre Arabie et Eurasie et est le siège d’une déformation intracontinental active comme l’atteste les nombreux tremblements de terre historiques qui s’y sont produits. Tous ces séismes, destructeurs, attestent d’une forte activité sismique régionale, et il est par conséquent important d'évaluer l’aléa sismique associé aux structures actives qui génère cette sismicité.Le travail présenté ici, expose les résultats de l’analyse de la tectonique active au niveau des terminaisons nord-ouest et sud-est de la faille de Pambak-Sevan-Syunik (PSSF), une des failles décrochant majeure qui traverse l'Arménie du NW au SE. La quantification des déformations en termes de géométrie, cinématique, vitesse de glissement et paléosismicité, en utilisant les méthodes de datation 3He cosmogénique, OSL/IRSL et radiocarbone, révèlent des comportements différents entre les deux régions.Au niveau de la terminaison nord-ouest, dans la région d’Amassia, la faille PSSF s’incurve vers l'ouest et se subdivise en deux branches de direction WNW-ESE, et de cinématique inverse, définissant une structure en pop-up. Nous estimons une vitesse de soulèvement de 0.5 ± 0.1 mm/an et une vitesse de raccourcissement NNE-SSW de 1.4 ± 0.6 mm/an. Ces résultats suggère que l’essentiel des ~2 mm/an de mouvement dextre estimés le long de la faille de PSSF sont absorbés au niveau du pop-up d’Amassia.Au niveau de la terminaison sud-est, dans la région du volcan Tsghuk, la faille PSSF semble disparaitre. Le peu d’activité tectonique est caractérisée par des failles normales sub-méridiennes associées à une légère composante décrochant dextre. Nous déterminons une vitesse de glissement vertical de ~0,2 mm/an, une vitesse d’extension ~EW de ~0,1 mm/an associée à une composante dextre de ~0,05 mm/an. Ces résultats suggèrent que le mouvement dextre observé le long de la faille de PSSF plus au nord, a été transféré sur d'autres failles plus à l'ouest dans le Karabakh (faille Hagari ou autres structures situés encore plus au NW).
https://tel.archives-ouvertes.fr/tel-01621440

NNT : 2016MONTT152
tel-01621440
https://tel.archives-ouvertes.fr/tel-01621440
https://tel.archives-ouvertes.fr/tel-01621440v2/document
https://tel.archives-ouvertes.fr/tel-01621440/file/2016_MKRTCHYAN_archivage.pdf

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
: Zebrafish, Danio rerio, is increasingly used as an animal model to study the effects of pharmaceuticals and environmental estrogens. As most of these estrogens have only been tested on human estrogen receptors (ERs), it is necessary to measure their effects on zebrafish ERs. In humans there are two distinct nuclear ERs (hERα and hERβ), whereas the zebrafish genome encodes three ERs, zfERα and two zfERβs (zfERβ1 and zfERβ2). In this study, we established HeLa-based reporter cell lines stably expressing each of the three zfERs. We first reported that estrogens more efficiently activate the zfERs at 28°C as compared to 37°C, thus reflecting the physiological temperature of zebrafish in wildlife. We then showed significant differences in the ability of agonist and antagonist estrogens to modulate activation of the three zfER isotypes in comparison to hERs. Environmental compounds (bisphenol A, alkylphenols, mycoestrogens) which are hER panagonists and hERβ selective agonists displayed greater potency for zfERα as compared to zfERβs. Among hERα selective synthetic agonists, PPT did not activate zfERα while 16α-LE2 was the most zfERα selective compound. Altogether, these results confirm that all hER ligands control in a similar manner the transcriptional activity of zfERs although significant differences in selectivity were observed among subtypes. The zfER subtype selective ligands that we identified thus represent new valuable tools to dissect the physiological roles of the different zfERs. Finally, our work also points out that care has to be taken in transposing the results obtained using the zebrafish as a model for human physiopathology.
ISSN: 0041-008X

inserm-01067804
http://www.hal.inserm.fr/inserm-01067804
http://www.hal.inserm.fr/inserm-01067804/document
http://www.hal.inserm.fr/inserm-01067804/file/pintot_et_al._manuscript.pdf
DOI : 10.1016/j.taap.2014.07.020

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
Background: The evaluation of geographical healthcare accessibility in residential areas provides crucial information to public policy. Traditional methods - such as Physician Population Ratios (PPR) or shortest travel time - offer only a one-dimensional view of accessibility. This paper developed an improved indicator: the Index of Spatial Accessibility (ISA) to measure geographical healthcare accessibility at the smallest available infra-urban level, that is, the Ilot Regroupe pour des Indicateurs Statistiques. Methods: This study was carried out in the department of Nord, France. Healthcare professionals are geolocalized using postal addresses available on the French state health insurance website. ISA is derived from an Enhanced Two-Step Floating Catchment Area (E2FCA). We have constructed a catchment for each healthcare provider, by taking into account residential building centroids, car travel time as calculated by Google Maps and the edge effect. Principal Component Analyses (PCA) were used to build a composite ISA to describe the global accessibility of different kinds of health professionals. Results: We applied our method to studying geographical healthcare accessibility for pregnant women, by selecting three types of healthcare provider: general practitioners, gynecologists and midwives. A total of 3587 healthcare providers are potentially able to provide care for inhabitants of the department of Nord. On average there are 92 general practitioners, 22 midwives and 21 gynecologists per 100,000 residents. The composite ISA for the three types of healthcare provider is 39 per 100,000 residents. A comparative analysis between ISA and physician-population ratios indicates that ISA represents a more even distribution whereas the physician-population ratios show an 'all-or-nothing' approach. Conclusion: ISA is a multidimensional and improved measure, which combines the volume of services relative to population size with the proximity of services relative to the population's location, available at the smallest feasible geographical scale. It could guide policy makers towards highlighting critical areas in need of more healthcare providers, and these areas should be earmarked for further knowledge-based policy making.
ISSN: 1475-9276

hal-01359567
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01359567
DOI : 10.1186/s12939-016-0411-z
PUBMED : 27485740

Éditeur(s) : HAL CCSD
Résumé : International audience
(Guava (Psidium guajava L.) is a tropical fruit widely consumed around the world. The study wascarried out on four selected guava varieties grown in Martinique. Two fruit harvests were gathered at two-yearintervals, at the green/yellow color change maturity stage. First, we established the homogeneity of all fruitbatches by bootstrapping, ANOVA, box plot and multiple comparison statistical analysis on physicalparameters. Red Supreme Ruby clearly differs from the other three varieties, whereas the results for CentenoProlific are between Beauséjour and Enana Cuba. We determined on puree obtained from a homogeneousbatch of each variety the physicochemical and functional properties as well as the antioxidant properties. Ourresults show that the combination of lycopene and vitamin C, and their synergistic mechanisms in the fruitextracts may be responsible for the high antioxidant activity of guava puree, and we demonstrate a statisticallysignificant positive correlation between EC50 and lycopene.
IOSR Journal of Environmental Science, Toxicology and Food Technology (IOSR-JESTFT)

hal-01672064
https://hal.univ-antilles.fr/hal-01672064
DOI : 10.9790/2402-1109015767

Éditeur(s) : Inter-research
Résumé : Vibriosis is a major disease problem in shrimp aquaculture. 'Syndrome 93' is a seasonal juvenile vibriosis caused by Vibrio penaeicida which affects Litopenaeus stylirostris in grow-out ponds in New Caledonia. This study assessed the toxic activities of extracellular products (ECPs) from V: penaeicida, V. alginolyticus and V, nigripulchritudo using in vivo injections in healthy juvenile L. stylirostris (= Penaeus stylirostris) and in vitro assays on shrimp primary cell cultures and the fish cell line epithelioma papulosum cyprini (EPC). Toxic effects of ECPs were demonstrated for all pathogenic Vibrio strains tested both in vivo and in vitro, but for shrimp only; no effect was observed on the fish cell line. ECP toxicity for New Caledonian V. penaeicida was found only after cultivation at low temperature (20 degrees C) and not at higher temperature (30 degrees C). This points to the fact that 'Syndrome 93' episodes are triggered by temperature drops. The assays used here demonstrate the usefulness of primary shrimp cell cultures to study virulence mechanisms of shrimp pathogenic bacteria.
Diseases Of Aquatic Organisms (0177-5103) (Inter-research), 2000-03 , Vol. 40 , N. 2 , P. 101-107

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/00000/10543/7600.pdf
DOI:10.3354/dao040101
http://archimer.ifremer.fr/doc/00000/10543/

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
All-trans retinoic acid (atRA) is the active form of vitamin A, known to activate retinoid receptors, especially the heterodimer retinoid X receptor (RXR):retinoic acid receptor (RAR) that otherwise may play a role in regulation of some drug transporters. The present study was designed to characterize the nature of human hepatic transporters that may be targeted by atRA and the heterodimer RXR:RAR. Exposure of human hepatoma HepaRG cells and primary human hepatocytes to 5μM atRA down-regulated mRNA levels of various sinusoidal solute carrier (SLC) influx transporters, including organic anion transporting polypeptide (OATP) 2B1, OATP1B1, organic cation transporter (OCT) 1 and organic anion transporter (OAT) 2, and induced those of the canalicular breast cancer resistance protein (BCRP). The retinoid concomitantly reduced protein expression of OATP2B1 and OATP1B1 and activity of OATPs and OCT1 and induced BCRP protein expression in HepaRG cells. Some transporters such as OATP1B3 and the bile salt export pump (BSEP) were however down-regulated by atRA in primary human hepatocytes, but induced in HepaRG cells, thus pointing out discrepancies between these two liver cell models in terms of detoxifying protein regulation. atRA-mediated repressions of OATP2B1, OATP1B1, OAT2 and OCT1 mRNA expression were finally shown to be counteracted by knocking-down expression of RARα and RXRα through siRNA transfection in HepaRG cells. atRA thus differentially regulated human hepatic drug transporters, mainly in a RXR:RAR-dependent manner, therefore establishing retinoids and retinoid receptors as modulators of liver drug transporter expression.
ISSN: 0928-0987

inserm-00804935
http://www.hal.inserm.fr/inserm-00804935
DOI : 10.1016/j.ejps.2013.01.005
PUBMED : 23352986

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Fault friction is a parameter that is difficult to assess along fault zones since its determination depends on the knowledge of any factor controlling the state of stress around faults. In brittle homogeneous rocks, a limited number of these factors, such as the shape of the fault surface, the vicinity of fault tips or the remote stress ratio, are crucial to constrain for this determination. In this paper, we propose to analyse a field example in which all these properties are met and where the nature of the slipped structure suggest differences in static friction. We compare the orientations of branching fractures at strike-slip relay zones between en echelon stylolites and en echelon joints both reactivated in shear. The field data are compared with both photoelastic and 3-D numerical models that consider the remote stress conditions and the role of the geometry of the strike-slip segments. Based on field observations, these analyses quantitatively demonstrate the significant role of fault friction on the local stress field orientation and subsequent fracture formation. This work points out that estimations of fault friction based on analyses of fracture patterns or in situ stresses must be accompanied with a thorough investigation of the 3-D fault shape, its segmentation and the remote stress state.
ISSN: 0191-8141

hal-00560999
https://hal.archives-ouvertes.fr/hal-00560999
DOI : 10.1016/j.jsg.2010.01.008

Éditeur(s) : Elsevier Science Bv
Résumé : The Var turbiditic system located in the Ligurian Sea (SE France) is an intermediate mud/sand-rich system. The particularity of the Var deep-sea fan is its single channel with abrupt bends and its asymmetric and hyper-developed levee on the right hand side: the Var Sedimentary Ridge. Long-term sediment accumulation on the Var Sedimentary Ridge makes this an ideal target for studying the link between onshore climate change and deep-sea turbidite stratigraphy. This paper focuses on the establishment of the first detailed stratigraphy of the levee, which is used to analyze the timing of overbank deposition throughout the last deglaciation. Main results indicate that high variability in turbidite frequencies and deposition rates along the Var Sedimentary Ridge are determined by two main parameters: 1) the progressive decrease of the levee height controlling the ability of turbidity currents to spill out from the channel onto the levee, and 2) climatic variations affecting the drainage basin, in particular changes in glacial condition since late Last Glacial Maximum to early Holocene. Compared to other deep-water areas, this study confirms the ability of turbiditic systems to record past climatic events on millennial timescales, and underlines the influence of European deglaciation on the observed decrease in turbidite activity in the Var canyon. The presence of a very narrow continental shelf and a single, large channel-levee system makes the Var Sedimentary Ridge a unique example of climate-controlled turbiditic accumulations. (C) 2010 Elsevier B.V. All rights reserved.
Marine Geology (0025-3227) (Elsevier Science Bv), 2011-01 , Vol. 279 , N. 1-4 , P. 148-161

Droits : 2010 Elsevier Ltd All rights reserved.
http://archimer.ifremer.fr/doc/00030/14104/11370.pdf
DOI:10.1016/j.margeo.2010.10.021
http://archimer.ifremer.fr/doc/00030/14104/

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
Background: The relative scarcity of Copia retrotransposons has been recently characterized in metazoans in comparison with the other superfamilies of LTR elements. Furthermore, Copia retrotransposons have often a particular dynamics that results in a highly predominant single clade of elements within a large host taxon, such as the GalEa-like retrotransposons in crustaceans. Taking advantage of the skyrocketing amount of genomic data available for fungi, we carried out the first large-scale comparative genomic analysis of the Copia clades in filamentous ascomycetes.Results: Screening 30 completely sequenced genomes allowed us to identify more than 2500 Copia copies with conserved LTR, which are distributed in 138 families. Their characterization revealed that fungal Copia diversity is much broader than previously thought with at least 27 clades, 23 of which likely correspond to new ones. While the Copia copy number is low in most species, the two clades GalEa and FunCo1 are widely distributed and highly dominate Copia content as they both account for 80% of the detected sequences.Conclusions: In Fungi, GalEa retrotransposons are restricted to Pezizomycotina in which they can make up an outstandingly high proportion of the genome (up to 10% in Cenococcum geophilum). At last, we revealed that fungal GalEa elements structurally differ from all other Copia elements with an absence of Primer Binding Site. These elements however harbor a Conserved Hairpin Site which is probably essential for their transposition.sequences.
ISSN: 1471-2164

Droits : http://creativecommons.org/licenses/by/
hal-01529914
http://hal.upmc.fr/hal-01529914
http://hal.upmc.fr/hal-01529914/document
http://hal.upmc.fr/hal-01529914/file/art_10.1186_s12864-017-3795-2.pdf
DOI : 10.1186/s12864-017-3795-2

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
I use GPS interseismic velocities and classic 2D elastic half-space models with a screw dislocation to estimate the long-term fault slip rate, locking depth, and the offset between the surface fault trace and the location of the dislocation below the seismogenic zone for 13 segments along 8 major strike-slip faults. Using deduced strike-slip rates and the position of the dislocation to normalize the interseismic velocities to facilitate comparison of spatial patterns of deformation, I show that no substantial differences can be detected, ruling out a large asymmetry in interseismic velocities across the 8 faults used in this study. Only the Carrizo Plain segment of the San Andreas Fault shows a significant asymmetry that cannot be explained by shifting the position of the dislocation at depth relative to the fault trace. However, the resulting perturbation is less than 10% of total strike-slip rate. Fault traces are usually curved, defining a concave side. When the dislocation at depth is significantly offset from the fault trace, the shift is always toward the block on the concave side of the fault trace. This suggests that the fault zone in the lower crust may develop a simpler geometry more consistent with relative motion across the fault than its upper seismogenic part constrained by the structural complexity of the brittle crust. Since the faults used in this study are at different times in their interseismic period, comparing the interseismic velocity fields across them allows identification of possible variations of the interseismic velocities with time. When normalized by slip rate and dislocation location, all the faults show the same interseismic strain with no significant differences between deduced locking depths. These comparisons suggest that if temporal variations occur as suggested by some dynamic earthquake cycle models, they are small and below the accuracy of the available geodetic measurements.
ISSN: 0040-1951

hal-01171753
https://hal.archives-ouvertes.fr/hal-01171753
DOI : 10.1016/j.tecto.2015.01.013